This
review
focuses
on
the
structure–property
correlation
and
bioimaging
application
of
luminescent
metal
nanoclusters,
which
feature
atomically
precise
structures,
diverse
optical
properties
excellent
biocompatibility.
Talanta Open,
Год журнала:
2024,
Номер
9, С. 100327 - 100327
Опубликована: Май 16, 2024
Gold
nanoparticles
(AuNPs)
have
become
the
focus
of
rapid
research
due
to
their
unique
optical
and
electronic
properties.
There
has
been
a
noticeable
increase
in
papers
relating
AuNPs,
with
over
71,000
publications
between
2019
2024.
AuNPs
possess
exceptional
stability,
low
resistance,
high
conductivity,
extensive
light
interaction,
making
them
well-suited
for
biological
sensing
applications.
This
literature
study
begins
by
examining
different
approaches
synthesizing
including
chemical,
physical,
methods,
before
exploring
use
as
biosensors.
A
comprehensive
examination
various
detection
localized
surface
plasmon
resonance
(LSPR),
luminescence,
surface-enhanced
Raman
scattering
(SERS),
(SPR),
electrochemical
properties,
is
facilitated
through
an
exploration
fundamental
principles
classification
We
primarily
on
using
medical
diagnostics,
highlighting
current
advancements
disease
AuNPs-based
biosensors
conditions
like
COVID-19,
dengue
fever,
diabetes.
The
review
emphasizes
achievements
synthesis
bright
prospects
biocompatible
efficient
biosensor
Advanced Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 3, 2025
Abstract
This
review
underscores
the
transformative
potential
of
photonic
nanomaterials
in
wearable
health
technologies,
driven
by
increasing
demands
for
personalized
monitoring.
Their
unique
optical
and
physical
properties
enable
rapid,
precise,
sensitive
real‐time
monitoring,
outperforming
conventional
electrical‐based
sensors.
Integrated
into
ultra‐thin,
flexible,
stretchable
formats,
these
materials
enhance
compatibility
with
human
body,
enabling
prolonged
wear,
improved
efficiency,
reduced
power
consumption.
A
comprehensive
exploration
is
provided
integration
devices,
addressing
material
selection,
light‐matter
interaction
principles,
device
assembly
strategies.
The
highlights
critical
elements
such
as
form
factors,
sensing
modalities,
data
communication,
representative
examples
skin
patches
contact
lenses.
These
devices
precise
monitoring
management
biomarkers
diseases
or
biological
responses.
Furthermore,
advancements
approaches
have
paved
way
continuum
care
systems
combining
multifunctional
sensors
therapeutic
drug
delivery
mechanisms.
To
overcome
existing
barriers,
this
outlines
strategies
design,
engineering,
system
integration,
machine
learning
to
inspire
innovation
accelerate
adoption
next‐generation
health,
showcasing
their
versatility
digital
applications.
Chemical & Biomedical Imaging,
Год журнала:
2024,
Номер
2(7), С. 462 - 480
Опубликована: Июнь 18, 2024
In
the
realm
of
nanomaterials,
atomically
precise
quasi-molecular
gold
nanoclusters
(AuNCs)
play
a
prime
role
due
to
their
unique,
stable,
and
highly
tunable
optical
properties.
They
are
extensively
structure-engineered
for
modulation
surface
electronic
states
toward
long
wavelength
photoluminescence,
particularly
in
NIR-II
(1000
1700
nm)
window.
Contrast
agents
with
emission
can
potentially
transform
imaging
terms
higher
spatial
resolution,
deeper
tissue
penetration,
reduced
autofluorescence.
These
advantages
allow
real-time
living
organisms
observing
disease
progression
treatment
response.
this
short
review,
we
discuss
origin
rationally
designed
AuNCs
application
high
resolution
vasculatures
hard
soft
structures
identification
pathological
conditions
such
as
stroke
injury.
Further,
recent
employment
these
rapidly
growing
field
tumor
theranostics
is
also
summarized.
Final
remarks
provided
on
scope
improvement
properties
persisting
challenges
clinical
translation.
PLoS ONE,
Год журнала:
2025,
Номер
20(2), С. e0316221 - e0316221
Опубликована: Фев. 6, 2025
Copper
ferrite
nanoparticles
for
use
as
MRI
contrast
agents
were
synthesized
using
two
different
methods.
A
novel
microwave-assisted
(MW)
solvothermal
method
was
developed
and
compared
to
a
conventional
12-hour
synthesis
(Reflux)
an
eco-friendlier
approach.
This
innovative
successfully
produced
with
enhanced
properties
traditional
materials.
The
nanoparticles’
morphological
magnetic
evaluated
tested
in
in-vivo
studies.
results
revealed
both
similarities
differences
between
the
amine-functionalized
copper
nanoparticles.
FTIR,
XRD,
HRTEM,
VSM
analyses
indicated
improved
CuFe
2
O
4
-NH
MW
particles,
while
AFM
confirmed
successful
polymer
encapsulation
of
For
sample,
76.8
wt%
23.2
magnetite
detected,
crystallite
sizes
8
±
nm
13
nm,
respectively.
In
Refl.
addition
these
phases,
larger
particles
(31.6
wt%)
also
formed.
DLS
analysis
demonstrated
that
sample
exhibited
excellent
colloidal
stability,
maintaining
its
size
distribution
aqueous
media
3
hours
without
aggregation,
unlike
which
showed
slight
aggregation.
displayed
superparamagnetic
behavior
(Ms:
15
emu/g,
Mr:
0
Hc:
Oe),
ferromagnetic
characteristics
40
1.35
30
Oe).
Both
samples
comparable
during
vitro
measurements,
showing
similar
T2*
relaxation
signal
characteristics.
Further
vivo
studies
induced
significant
hypointense
changes.
study
provides
valuable
insights
into
synthesis,
properties,
potential
applications
materials,
emphasizing
importance
eco-friendly
methods
optimization
ferrite-based
agents.
Food Chemistry,
Год журнала:
2024,
Номер
460, С. 140550 - 140550
Опубликована: Июль 20, 2024
An
emerging
fluorescent
ratiometric
aptasensor
based
on
gold
nanoclusters
(AuNCs)
with
aggregation-induced
emission
(AIE)
properties
was
prepared
and
studied
for
deoxynivalenol
(DON)
detection.
The
used
red
AuNCs
Abstract
Fluorescence
signal
“turn‐on”
lateral
flow
immunoassay
(FONLFA)
through
nanomaterial
labeled
quenching
fluorescent
has
shown
significant
potential
for
the
detection
of
small
molecules.
However,
immobilization
on
nitrocellulose
(NC)
membrane
commonly
requires
tedious
chemical
modification
and
only
a
few
combinations
fluorescence
donor
quencher
have
been
applied
in
FONLFA.
In
this
work,
bright
metal
nanoclusters
(Prot‐AuNCs)
were
prepared
self‐assembled
into
Prot‐AuNCs/antigen
aggregates
with
three
typical
molecule
antigens,
respectively.
The
can
be
readily
immobilized
surface
NC
membrane,
indicating
that
strip
fabrication
strategy
good
versatility.
Moreover,
we
evaluated
performances
FONLFA
platform
by
using
carbendazim
as
model
target
investigated
four
nanomaterials
colorimetric
nanoprobes
quenchers.
We
found
all
demonstrated
significantly
improved
naked
eye
sensitivity
(vLOD)
limits
(LODs)
quantitative
analysis.
Among
them,
combing
Fe‐polydopamine
nanoparticles
above
aggregates,
mode
achieved
200‐fold
vLOD
(0.05
ng
mL
−1
)
compared
conventional
AuNPs‐based
(AuNPs‐LFA)
(10
).
addition,
LOD
analysis
also
was
22‐fold
whole
test
process
completed
within
10
min.
With
advantages
efficient
fabrication,
extraordinary
sensitization,
biocompatibility,
our
is
expected
to
great
rapid
various