Recent progress in polyaniline and its composites; Synthesis, properties, and applications

European Polymer Journal, Год журнала: 2024, Номер 210, С. 112948 - 112948

Опубликована: Март 17, 2024

Язык: Английский

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Synthesis and characterization of chitosan/carbon quantum dots/Fe2O3 nanocomposite comprising curcumin for targeted drug delivery in breast cancer therapy

International Journal of Biological Macromolecules, Год журнала: 2023, Номер 249, С. 125788 - 125788

Опубликована: Июль 10, 2023

Язык: Английский

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A review on carbon material-metal oxide-conducting polymer and ionic liquid as electrode materials for energy storage in supercapacitors

Ionics, Год журнала: 2024, Номер 30(4), С. 1857 - 1870

Опубликована: Фев. 12, 2024

Язык: Английский

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Development of a labeled-free and labeled electrochemical aptasensor for the detection of cancer antigen 125 by using magnetic g-C3N4/MoS2 nanocomposite

Sensors and Actuators Reports, Год журнала: 2024, Номер 7, С. 100195 - 100195

Опубликована: Апрель 24, 2024

Efficient and timely detection of cancer biomarkers is pivotal for enhancing treatment outcomes mitigating patient mortality. This study addresses the pressing need a swift, accurate, non-invasive method to identify antigen 125 (CA125), vital biomarker in ovarian cancer. Leveraging growing prominence nano-biosensors their high selectivity sensitivity, we present development characterization an innovative electrochemical nano-biosensor. The sensor, featuring aptamer strands immobilized on glassy carbon electrode modified with graphitic nitrides, molybdenum disulfide, magnetic nanoparticles (g-C3N4/MoS2/Fe3O4), demonstrates superior sensitivity accuracy CA125 detection. Utilizing methylene blue labeled ferrocyanide label-free detection, our aptasensor achieves low limit (LOD) at 0.202 U.mL−1 0.215 U.mL−1, respectively, broad range from 2 10 U.mL−1. exhibits pronounced affinity CA125, demonstrating enhanced stability compared other biomolecules. Crucially, evaluation both normal serum samples underscores aptasensor's remarkable performance. These findings not only establish robust foundation future research diagnosis but also highlight potential clinical impact nano-biosensor advancing early methodologies.

Язык: Английский

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Electrochemical synthesis of hybrid nanostructure of nickel cobalt phosphide/molybdenum disulfide on nickel foam as an effective electrode material in supercapacitor

Materials Chemistry and Physics, Год журнала: 2024, Номер 317, С. 129150 - 129150

Опубликована: Март 15, 2024

Язык: Английский

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Aptamer-enabled electrochemical bioplatform utilizing surface-modified g-C3N4/MoS2/PANI nanocomposite for detection of CA125 biomarker

Sensing and Bio-Sensing Research, Год журнала: 2024, Номер 45, С. 100669 - 100669

Опубликована: Июнь 28, 2024

Detecting ovarian cancer at an early stage is crucial for enhancing patient outcomes, underscoring the demand efficient and non-invasive detection method. Cancer antigen 125 (CA125) a vital biomarker in detection, there pressing to develop quick, sensitive, simple Nanobiosensors are increasingly being used by scientists due their high selectivity sensitivity, allowing swift precise of wide range biomarkers. This study aimed design fabricate electrochemical nanobiosensor that could accurately selectively detect CA125. The employed graphitic carbon nitrides, molybdenum disulfide, polyaniline (g-C3N4/MoS2/PANI) stabilize aptamer strands on modified glassy electrode. aptasensor was perform labeled CA125, utilizing methylene blue label-free ferrocyanide methods. Ferrocyanide limits were determined be 0.196 U.mL−1 blue, with linear 2–10 detection. results showed electrode exhibited towards CA125 superior stability compared other biomolecules. also displayed impressive performance when analyzing serum patients healthy people. These findings hold significant promise future investigation diagnosis. novel may aid management cancer, ultimately leading better outcomes.

Язык: Английский

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Cyclodextrin-based nanocarriers as promising scaffolds for overcoming challenges of doxorubicin delivery in cancer chemotherapy

Carbohydrate Polymer Technologies and Applications, Год журнала: 2025, Номер unknown, С. 100677 - 100677

Опубликована: Янв. 1, 2025

Язык: Английский

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CRISPR/Cas14a integrated with DNA walker based on magnetic self-assembly for human papillomavirus type 16 oncoprotein E7 ultrasensitive detection

Biosensors and Bioelectronics, Год журнала: 2025, Номер 272, С. 117135 - 117135

Опубликована: Янв. 5, 2025

Язык: Английский

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Homogeneous Aptasensor with Electrochemical and Electrochemiluminescence Dual Detection Channels Enabled by Nanochannel-Based Probe Enrichment and DNase I Cleavage for Tumor Biomarker Detection

Molecules, Год журнала: 2025, Номер 30(3), С. 746 - 746

Опубликована: Фев. 6, 2025

Homogeneous aptasensors that eliminate the need for probe labeling or immobilization hold significant potential rapid detection of tumor biomarkers. Herein, a homogeneous aptasensor with electrochemical (EC) and electrochemiluminescence (ECL) dual channels was developed by integrating nanochannel-based enrichment DNase I cleavage selective biomarker, carbohydrate antigen 125 (CA125). A two-dimensional (2D) composite prepared assembling CA125-specific aptamer cationic tris(2,2′-bipyridyl)Ru(II) (Ru(bpy)32+), which exhibited both EC ECL properties, onto graphene oxide (GO) nanosheets (Ru(bpy)32+/Apt@GO). vertically ordered mesoporous silica film (VMSF) ultrasmall, uniform, aligned nanochannel arrays rapidly grown on inexpensive disposable indium tin (ITO) electrode, forming interface. Due to size exclusion effect ultrasmall nanochannels in VMSF, Ru(bpy)32+/Apt@GO unable penetrate nanochannels, resulting no detectable Ru(bpy)32+ signal electrode. Upon specific recognition CA125 aptamer, an aptamer-CA125 complex formed subsequently detached from GO. then cleaved complex, releasing allowing dissociate into solution. This enzymatic enabled re-enter binding cycle, amplifying release The electrostatic adsorption VMSF significantly enhanced signals. constructed linear range 0.1 U/mL 100 ng/mL, limit (LOD) 91 mU/mL. For detection, detected over 0.001 U/mL, LOD as low 0.4 demonstrated excellent selectivity successfully applied dual-mode EC/ECL fetal bovine serum samples.

Язык: Английский

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Enhanced supercapacitor performance using] Caff-TEA[+]ZnBr3[− ionic liquid electrode in aqueous Na2SO4 electrolyte

Journal of Energy Storage, Год журнала: 2025, Номер 109, С. 115232 - 115232

Опубликована: Янв. 8, 2025

Язык: Английский

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