Sensors and Actuators B Chemical, Год журнала: 2024, Номер 417, С. 136144 - 136144
Опубликована: Июнь 14, 2024
Язык: Английский
Advanced Functional Materials, Год журнала: 2024, Номер 34(48)
Опубликована: Июнь 29, 2024
Abstract While existing polyoxometalates (POMs) are predominantly utilized in a range of energy devices, their potential bioelectronics and optoelectronics, particularly organic photoelectrochemical transistors (OPECTs), remains unexplored. Here, the POMs this aspect is unveiled by POM/sulfide‐gated OPECT. The representative PW 12 /ZnIn 2 S 4 with cascading light‐harvesting enzyme‐like functionality enables unique on‐off OPECT operation. incorporation facilitates separation photogenerated charge carriers across heterojunction interface, consequently inducing pronounced gating effect. Linking CRISPR/Cas13a system correlating target miRNA‐21 biological generation H O , will enable polymerization dopamine into polydopamine thus sensitively inhibit gating. Experimental results demonstrated that developed sensor achieved good analytical performance detection limit as low 3.9 f m . This study demonstrates Given large family multifunction POMs, its implications diverse optoelectronics expected.
Язык: Английский
Процитировано
34
Advanced Functional Materials, Год журнала: 2024, Номер 34(45)
Опубликована: Май 31, 2024
Abstract The pursuit of high on‐to‐off ratio ( I On / Off ), as one the important performances for organic electrochemical transistor (OECT) has been ongoing, but to date, limited solutions are available. interaction between light and matter demonstrated a rich source advanced electronic applications. However, its potential in modulation not fully explored. Herein, challenge is addressed through unique light‐material interplay, which represented by photoelectrochemical (OPECT) gated photosensitive COF‐LZU1 on mixed‐ligand MOF (COF‐on‐MOF) upon appropriate exposure illumination. Notably, interplay COF‐on‐MOF can adjust device physics, optimizing maximum enhancing signal transduction. Toward bio‐application, via exonuclease‐assisted cyclic cleavage amplification hybridization chain reaction, such validated highly sensitive detection capabilities human T‐cell lymphotropic virus type II (HTLV‐II) DNA down 0.003 fM. This study features possibility Ag/AgCl‐like photogating transistors light‐matter interplay.
Язык: Английский
Процитировано
21
eScience, Год журнала: 2025, Номер unknown, С. 100374 - 100374
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
11
Analytical Chemistry, Год журнала: 2024, Номер 96(5), С. 1948 - 1956
Опубликована: Янв. 24, 2024
Organic electrochemical transistors with signal amplification and good stability are expected to play a more important role in the detection of environmental pollutants. However, bias voltage at gate may have an effect on activity vulnerable biomolecules. In this work, novel organic photoelectrochemical transistor (OPECT) aptamer biosensor was developed for di(2-ethylhexyl) phthalate (DEHP) by combining analysis transistor, where MXene/Bi2S3/CdIn2S4 employed as photoactive material, target-dependent DNA hybridization chain reaction used unit, Ru(NH3)63+ selected enhancement molecule. The poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)-based OPECT modulated photosensitive material achieved high current gain nearly thousand times zero voltage. signal-on sensing platform realized sensitive specific DEHP, range 1–200 pM minimum limit 0.24 under optimized experimental conditions, its application real water samples also evaluated satisfactory results. Hence, construction biosensing not only provides promising tool DEHP but reveals great potential other toxins.
Язык: Английский
Процитировано
14
TrAC Trends in Analytical Chemistry, Год журнала: 2025, Номер unknown, С. 118161 - 118161
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
1
Biosensors and Bioelectronics, Год журнала: 2024, Номер 257, С. 116346 - 116346
Опубликована: Апрель 27, 2024
Язык: Английский
Процитировано
9
Analytical Chemistry, Год журнала: 2024, Номер 96(49), С. 19822 - 19832
Опубликована: Ноя. 22, 2024
Hydrogen sulfide (H2S) is an important bioactive molecule that plays a significant role in various functions, particularly the living brain, where it closely linked to cognition, memory, and several neurological diseases. Consequently, developing effective detection methods for H2S essential studying brain functions underlying mechanisms of these This study aims construct novel photoelectrochemical (PEC) microelectrode Ti/TiO2@HSP quantitative monitoring levels brain. The PEC formed by covalently bonding specifically designed organic probe HSP, which possesses D-π–A structure, surface TiO2 nanotubes generated via situ anodic oxidation titanium wire. HSP can effectively react with generate photocurrent response under long-wavelength excitation light (560 nm), thereby achieving H2S. sensor demonstrates high sensitivity good selectivity. In vivo experiments utilizing enable dynamic changes across regions mouse findings reveal normal mice, concentration hippocampus significantly higher than striatum cerebral cortex. Additionally, following propargylglycine drug stimulation, concentrations different were observed decrease, most substantial reduction noted hippocampus. suggests cystathionine γ-lyase (CSE) primary enzyme responsible production this area, while exhibits less pronounced decrease concentration, indicating reliance on alternative enzymatic pathways production. Therefore, not only successfully develops high-performance but also provides new experimental tools theoretical foundations further exploring roles neurophysiological pathological processes.
Язык: Английский
Процитировано
7
Advanced Functional Materials, Год журнала: 2025, Номер unknown
Опубликована: Март 2, 2025
Abstract Organic photoelectrochemical transistor (OPECT) as a photo‐electric‐biological technology, is shown considerable potential for high‐performance detection in biological sensing. High gating effect and current always pursuit to improve the performances of OPECT, but date, their inherent channel materials invariant structure limit further development. The challenge addressed through new bipolar‐driven OPECT signal amplification efficient modulation. Herein, inspired by self‐powered (PEC) systems, enhancement‐mode poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) powered Z‐scheme COF/Cu 2 O@Cu PtNCs photocathode CdIn S 4 photoanode proposed. It exhibits an enhanced remarkable gain ≈7613, which much higher than single‐photoelectrode ones will have beneficial impact on achieving sensitive, portable, reliable sensing devices. Moreover, sandwich system composed multifunctional COF‐based nanomaterials target‐mediated biomimetic precipitation reaction designed upon photocathode, resulting dual realizing alpha‐fetoprotein (AFP) with linear range 32 fg mL −1 –10 ng low 22 .
Язык: Английский
Процитировано
1
ACS Sensors, Год журнала: 2024, Номер 9(2), С. 988 - 994
Опубликована: Янв. 23, 2024
Herein, the first iontronic photoelectrochemical (PEC) biorecognition probing is devised by rational engineering of a dual-functional bioconjugate, i.e., light-sensitive intercalated structural DNA, as smart gating module confined within nanotip, which could respond to both incident light and biotargets interest. Light stimulation bioconjugate intensify negative charge at nano-orifice sustain enhanced ionic current. The presence proteins (e.g., acetylcholinesterase, AChE) or nucleic acids microRNA (miR)-10b) lead release with altered signaling. practical applicability methodology confirmed AChE detection in human serum miR-10b single cells.
Язык: Английский
Процитировано
6
Analytical Chemistry, Год журнала: 2024, Номер 96(16), С. 6444 - 6449
Опубликована: Апрель 10, 2024
As two mainstream ionic detection techniques, current rectification (ICR) suffers from large fluctuations in trace level detection, while resistive-pulse sensing (RPS) encounters easy clogs high-concentration detection. By rationally matching the nanopore size with DNA tetrahedron (TDN), this work bridges techniques to achieve reliable wide linearity. a representative analyte, miRNA-10b could specifically combine and release TDN interior wall, which thus induced simultaneous generation of distinct ICR RPS signals. The signals be attributed balance between effective orifice surface charge density inner were by complex passing through nanopore. Such an operation contributed range 1 fM-1 nM good feasibility method is also validated single-cell real plasma
Язык: Английский
Процитировано
5