Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
34(48)
Published: June 29, 2024
Abstract
While
existing
polyoxometalates
(POMs)
are
predominantly
utilized
in
a
range
of
energy
devices,
their
potential
bioelectronics
and
optoelectronics,
particularly
organic
photoelectrochemical
transistors
(OPECTs),
remains
unexplored.
Here,
the
POMs
this
aspect
is
unveiled
by
POM/sulfide‐gated
OPECT.
The
representative
PW
12
/ZnIn
2
S
4
with
cascading
light‐harvesting
enzyme‐like
functionality
enables
unique
on‐off
OPECT
operation.
incorporation
facilitates
separation
photogenerated
charge
carriers
across
heterojunction
interface,
consequently
inducing
pronounced
gating
effect.
Linking
CRISPR/Cas13a
system
correlating
target
miRNA‐21
biological
generation
H
O
,
will
enable
polymerization
dopamine
into
polydopamine
thus
sensitively
inhibit
gating.
Experimental
results
demonstrated
that
developed
sensor
achieved
good
analytical
performance
detection
limit
as
low
3.9
f
m
.
This
study
demonstrates
Given
large
family
multifunction
POMs,
its
implications
diverse
optoelectronics
expected.
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
34(45)
Published: May 31, 2024
Abstract
The
pursuit
of
high
on‐to‐off
ratio
(
I
On
/
Off
),
as
one
the
important
performances
for
organic
electrochemical
transistor
(OECT)
has
been
ongoing,
but
to
date,
limited
solutions
are
available.
interaction
between
light
and
matter
demonstrated
a
rich
source
advanced
electronic
applications.
However,
its
potential
in
modulation
not
fully
explored.
Herein,
challenge
is
addressed
through
unique
light‐material
interplay,
which
represented
by
photoelectrochemical
(OPECT)
gated
photosensitive
COF‐LZU1
on
mixed‐ligand
MOF
(COF‐on‐MOF)
upon
appropriate
exposure
illumination.
Notably,
interplay
COF‐on‐MOF
can
adjust
device
physics,
optimizing
maximum
enhancing
signal
transduction.
Toward
bio‐application,
via
exonuclease‐assisted
cyclic
cleavage
amplification
hybridization
chain
reaction,
such
validated
highly
sensitive
detection
capabilities
human
T‐cell
lymphotropic
virus
type
II
(HTLV‐II)
DNA
down
0.003
fM.
This
study
features
possibility
Ag/AgCl‐like
photogating
transistors
light‐matter
interplay.
Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
96(5), P. 1948 - 1956
Published: Jan. 24, 2024
Organic
electrochemical
transistors
with
signal
amplification
and
good
stability
are
expected
to
play
a
more
important
role
in
the
detection
of
environmental
pollutants.
However,
bias
voltage
at
gate
may
have
an
effect
on
activity
vulnerable
biomolecules.
In
this
work,
novel
organic
photoelectrochemical
transistor
(OPECT)
aptamer
biosensor
was
developed
for
di(2-ethylhexyl)
phthalate
(DEHP)
by
combining
analysis
transistor,
where
MXene/Bi2S3/CdIn2S4
employed
as
photoactive
material,
target-dependent
DNA
hybridization
chain
reaction
used
unit,
Ru(NH3)63+
selected
enhancement
molecule.
The
poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)-based
OPECT
modulated
photosensitive
material
achieved
high
current
gain
nearly
thousand
times
zero
voltage.
signal-on
sensing
platform
realized
sensitive
specific
DEHP,
range
1–200
pM
minimum
limit
0.24
under
optimized
experimental
conditions,
its
application
real
water
samples
also
evaluated
satisfactory
results.
Hence,
construction
biosensing
not
only
provides
promising
tool
DEHP
but
reveals
great
potential
other
toxins.
ACS Sensors,
Journal Year:
2024,
Volume and Issue:
9(2), P. 988 - 994
Published: Jan. 23, 2024
Herein,
the
first
iontronic
photoelectrochemical
(PEC)
biorecognition
probing
is
devised
by
rational
engineering
of
a
dual-functional
bioconjugate,
i.e.,
light-sensitive
intercalated
structural
DNA,
as
smart
gating
module
confined
within
nanotip,
which
could
respond
to
both
incident
light
and
biotargets
interest.
Light
stimulation
bioconjugate
intensify
negative
charge
at
nano-orifice
sustain
enhanced
ionic
current.
The
presence
proteins
(e.g.,
acetylcholinesterase,
AChE)
or
nucleic
acids
microRNA
(miR)-10b)
lead
release
with
altered
signaling.
practical
applicability
methodology
confirmed
AChE
detection
in
human
serum
miR-10b
single
cells.
Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
96(16), P. 6444 - 6449
Published: April 10, 2024
As
two
mainstream
ionic
detection
techniques,
current
rectification
(ICR)
suffers
from
large
fluctuations
in
trace
level
detection,
while
resistive-pulse
sensing
(RPS)
encounters
easy
clogs
high-concentration
detection.
By
rationally
matching
the
nanopore
size
with
DNA
tetrahedron
(TDN),
this
work
bridges
techniques
to
achieve
reliable
wide
linearity.
a
representative
analyte,
miRNA-10b
could
specifically
combine
and
release
TDN
interior
wall,
which
thus
induced
simultaneous
generation
of
distinct
ICR
RPS
signals.
The
signals
be
attributed
balance
between
effective
orifice
surface
charge
density
inner
were
by
complex
passing
through
nanopore.
Such
an
operation
contributed
range
1
fM-1
nM
good
feasibility
method
is
also
validated
single-cell
real
plasma
Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
96(49), P. 19822 - 19832
Published: Nov. 22, 2024
Hydrogen
sulfide
(H2S)
is
an
important
bioactive
molecule
that
plays
a
significant
role
in
various
functions,
particularly
the
living
brain,
where
it
closely
linked
to
cognition,
memory,
and
several
neurological
diseases.
Consequently,
developing
effective
detection
methods
for
H2S
essential
studying
brain
functions
underlying
mechanisms
of
these
This
study
aims
construct
novel
photoelectrochemical
(PEC)
microelectrode
Ti/TiO2@HSP
quantitative
monitoring
levels
brain.
The
PEC
formed
by
covalently
bonding
specifically
designed
organic
probe
HSP,
which
possesses
D-π–A
structure,
surface
TiO2
nanotubes
generated
via
situ
anodic
oxidation
titanium
wire.
HSP
can
effectively
react
with
generate
photocurrent
response
under
long-wavelength
excitation
light
(560
nm),
thereby
achieving
H2S.
sensor
demonstrates
high
sensitivity
good
selectivity.
In
vivo
experiments
utilizing
enable
dynamic
changes
across
regions
mouse
findings
reveal
normal
mice,
concentration
hippocampus
significantly
higher
than
striatum
cerebral
cortex.
Additionally,
following
propargylglycine
drug
stimulation,
concentrations
different
were
observed
decrease,
most
substantial
reduction
noted
hippocampus.
suggests
cystathionine
γ-lyase
(CSE)
primary
enzyme
responsible
production
this
area,
while
exhibits
less
pronounced
decrease
concentration,
indicating
reliance
on
alternative
enzymatic
pathways
production.
Therefore,
not
only
successfully
develops
high-performance
but
also
provides
new
experimental
tools
theoretical
foundations
further
exploring
roles
neurophysiological
pathological
processes.
Chinese Journal of Chemistry,
Journal Year:
2024,
Volume and Issue:
42(17), P. 1999 - 2004
Published: April 25, 2024
Comprehensive
Summary
We
report
herein
the
first
observation
of
MOF
nanozyme
enabling
dual‐functional
photo‐induced
charge
transfer
and
biomimetic
precipitation
for
advanced
organic
photoelectrochemical
transistor
(OPECT)
bioanalysis.
Specifically,
Fe/Co‐MIL‐88,
serving
simultaneously
as
semiconductor
nanozyme,
was
explored
a
gating
module
in
OPECT.
Upon
light
illumination,
it
could
accelerate
photogate
to
produce
enhanced
voltage.
Meanwhile,
its
catalytic
property
efficiently
block
nanopores
Fe/Co‐MIL‐88
thus
alter
device
characteristics.
The
generic
bioanalytical
potential
such
rationale
then
demonstrated
with
an
aptasensing
assisted
by
magnetic
separation.
This
work
represents
exploration
from
nanozymes
OPECT
bioanalysis,
is
expected
attract
more
interest
various
novel
optoelectronic
bioanalytics.
