Water Research,
Год журнала:
2022,
Номер
222, С. 118878 - 118878
Опубликована: Июль 18, 2022
This
study
aimed
to
provide
insights
into
the
risk
posed
by
psychopharmaceuticals
and
illicit
drugs
in
European
surface
waters,
identify
current
knowledge
gaps
hampering
this
assessment.
First,
availability
quality
of
data
on
concentrations
waters
(occurrence)
toxicity
aquatic
organisms
(hazard)
were
reviewed.
If
both
occurrence
ecotoxicity
available,
quotients
(risk)
calculated.
Where
abundant
a
species
sensitivity
distribution
(SSD)
was
constructed,
from
which
hazardous
concentration
for
5%
(HC5)
derived,
allowing
derive
integrated
multi-species
risks.
A
total
702
compounds
categorised
as
based
combination
all
502
anatomical
therapeutic
class
(ATC)
'N'
pharmaceuticals
list
according
Dutch
Opium
Act.
Of
these,
343
(49%)
returned
data,
while
only
105
(15%)
data.
Moreover,
many
tests
used
irrelevant
endpoints
neurologically
active
compounds,
such
mortality,
may
underestimate
hazard
psychopharmaceuticals.
Due
limitations,
risks
could
be
assessed
87
(12%)
with
23
(3.3%)
indicating
potential
risk,
several
highly
prescribed
neither
nor
Primary
bottlenecks
calculation
included
lack
diversity
test
ecotoxicological
end
points,
large
disparities
between
well
studied
understudied
identified
merit
concern,
that
any
driving
research
priorities.
Despite
gaps,
we
concluded
presence
substantial
part
(26%)
data-rich
present
an
ecological
non-target
organisms.
Abstract
Access
to
safe
water
is
a
crucial
factor
in
determining
environmental
sustainability,
public
health,
and
economic
prosperity.
Endocrine
disrupting
compounds
(EDCs)
are
an
contaminant
of
growing
concern,
which
undermine
the
safety
drinking
water.
The
potential
health
issues
EDCs
not
fully
understood
yet
due
there
being
relatively
scarce
research
on
their
exposure
associated
risks
via
consumption.
Because
ineffective
supply
systems
unknown
risk
perceptions
water,
role
perceived
ensuring
access
remains
unknown,
contributing
occurrence
such
global
system.
Integrating
preventive
measures
with
multibarrier
approach
highly
challenging
because
low
awareness
political
responsibility,
as
well
nature
characteristics
themselves.
In
addition
reviewing
public-perceived
this
article
focuses
building
bases
knowledge
for
better
understanding
quality
relative
hazards
surrounding
from
perspectives
human
risk.
A
conceptual
model
illustrates
factors
that
potentially
influence
perception
regard
only
but
also
other
issues.
Ensuring
requires
interventions
incorporate
communication
governance,
providing
insights
into
political,
economic,
social,
changes.
