SARS-CoV-2: sewage surveillance as an early warning system and challenges in developing countries DOI Creative Commons
Deepak Panchal, Om Prakash, Prakash Bobde

и другие.

Environmental Science and Pollution Research, Год журнала: 2021, Номер 28(18), С. 22221 - 22240

Опубликована: Март 17, 2021

Transmission of novel coronavirus (SARS-CoV-2) in humans happens either through airway exposure to respiratory droplets from an infected patient or by touching the virus contaminated surface objects (fomites). Presence SARS-CoV-2 human feces and its passage sewage system is emerging concern for public health. Pieces evidence occurrence viral RNA municipal wastewater (sewage) systems have not only warned reinforcing treatment facilities but also suggest that these can be monitored get epidemiological data checking trend COVID-19 infection community. This review summarizes persistence with emphasis on possible water environment contamination. Monitoring via sewage-based epidemiology could deliver promising information regarding rate providing a valid complementary tool tracking diagnosing across communities. Tracking act as early warning alerting health authorities necessary actions. Given impracticality testing every citizen limited diagnostic resources, it imperative tested system. The need development robust sampling strategies subsequent detection methodologies challenges developing countries are discussed.

Язык: Английский

The Fourth-Revolution in the Water Sector Encounters the Digital Revolution DOI
Manel Garrido‐Baserba, Lluís Corominas, Ulises Cortés

и другие.

Environmental Science & Technology, Год журнала: 2020, Номер 54(8), С. 4698 - 4705

Опубликована: Март 10, 2020

The so-called fourth revolution in the water sector will encounter Big data and Artificial Intelligence (AI) revolution. current surplus stemming from all types of devices together with relentless increase computer capacity is revolutionizing almost existing sectors, not be an exception. Combining power analytics (including AI) future urban infrastructure represents a significant untapped opportunity for operation, maintenance, rehabilitation to achieve economic environmental sustainability. However, such progress may catalyze socio-economic changes cross boundaries (e.g., service, health, business) as appearance new needs business models influence job market. Such impact academic forms research based on large amounts possible, requested by technology industrial sector. Research development enabling technological approaches more effective management strategies are needed ensure that emerging framework meet societal needs. feature further elucidates complexities possibilities associated collaborations.

Язык: Английский

Процитировано

90

Current and future perspectives for wastewater-based epidemiology as a monitoring tool for pharmaceutical use DOI
Tim Boogaerts, Fahad Ahmed, Phil M. Choi

и другие.

The Science of The Total Environment, Год журнала: 2021, Номер 789, С. 148047 - 148047

Опубликована: Май 26, 2021

Язык: Английский

Процитировано

82

Wastewater-Based Epidemiology to monitor COVID-19 outbreak: Present and future diagnostic methods to be in your radar DOI Creative Commons
‪Damià Barceló

Case Studies in Chemical and Environmental Engineering, Год журнала: 2020, Номер 2, С. 100042 - 100042

Опубликована: Сен. 1, 2020

The WHO has declared the COVID-19 epidemic on January 31, 2020. This virus infected millions of people worldwide in just a few months. Shortly afterwards, National Medical Products Administration (NMPA) announced nucleic acid testing as gold standard for detection. Antibody is used well supplementary test suspected cases where detection was negative. In short, acid–based polymerase chain reaction (PCR) mainstream method clinical samples SARS-CoV-2 wastewaters. First data collected around globe were reported last months being part so-called Wastewater-Based Epidemiology (WBE) approach. Selection concentration methods and primers, laboratory inter-comparison various modalities PCR complex wastewater matrices flagged up main bullets that require urgent improvement. Novel approaches to enhance sensitivity, speed automate streamlined will be discussed here well. list comprises devices mainly purposes like Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), Digital PCR, Lab-on-a-chip (LOC) related platforms Biosensors. devoted identification biomolecules target Covid-19 outbreak based inflammatory response biomarkers among others. To this end opinion paper brings discussion issue its limitations new diagnostic WBE.

Язык: Английский

Процитировано

71

Microbiome Analysis for Wastewater Surveillance during COVID-19 DOI Creative Commons
Kyle D. Brumfield, Menu Leddy, Moiz Usmani

и другие.

mBio, Год журнала: 2022, Номер 13(4)

Опубликована: Июнь 21, 2022

Wastewater surveillance (WS), when coupled with advanced molecular techniques, offers near real-time monitoring of community-wide transmission SARS-CoV-2 and allows assessing mitigating COVID-19 outbreaks, by evaluating the total microbial assemblage in a community. Composite wastewater samples (24 h) were collected weekly from manhole between December 2020 November 2021 Maryland, USA. RT-qPCR results showed concentrations RNA recovered reflected incidence cases. When drastic increase was detected February 2021, selected for microbiome analysis (DNA metagenomics, metatranscriptomics, targeted sequencing). Targeted sequencing allowed detection important genetic mutations, such as spike: K417N, D614G, P681H, T716I, S982A, D1118H, commonly associated increased cell entry reinfection. Microbiome RNA) provided insight respect to human health-related factors, including pathogens their virulence/antibiotic resistance genes. Specific species comprising correlated RNA, suggesting potential association infection. Climatic conditions, namely, temperature, related wastewater, having been monitored part an environmental risk score assessment carried out this study. In summary, provides useful public health information, hence, valuable tool proactively detect characterize pathogenic agents circulating effect, metagenomics can serve early warning system communicable diseases, providing larger source information departments officials.

Язык: Английский

Процитировано

59

SARS-CoV-2: sewage surveillance as an early warning system and challenges in developing countries DOI Creative Commons
Deepak Panchal, Om Prakash, Prakash Bobde

и другие.

Environmental Science and Pollution Research, Год журнала: 2021, Номер 28(18), С. 22221 - 22240

Опубликована: Март 17, 2021

Transmission of novel coronavirus (SARS-CoV-2) in humans happens either through airway exposure to respiratory droplets from an infected patient or by touching the virus contaminated surface objects (fomites). Presence SARS-CoV-2 human feces and its passage sewage system is emerging concern for public health. Pieces evidence occurrence viral RNA municipal wastewater (sewage) systems have not only warned reinforcing treatment facilities but also suggest that these can be monitored get epidemiological data checking trend COVID-19 infection community. This review summarizes persistence with emphasis on possible water environment contamination. Monitoring via sewage-based epidemiology could deliver promising information regarding rate providing a valid complementary tool tracking diagnosing across communities. Tracking act as early warning alerting health authorities necessary actions. Given impracticality testing every citizen limited diagnostic resources, it imperative tested system. The need development robust sampling strategies subsequent detection methodologies challenges developing countries are discussed.

Язык: Английский

Процитировано

58