Environmental Pollution,
Год журнала:
2023,
Номер
331, С. 121878 - 121878
Опубликована: Май 25, 2023
The
lack
of
data
on
the
chronic
effects
chloroacetanilide
herbicide
metabolites
non-target
aquatic
organisms
creates
a
gap
in
knowledge
about
comprehensive
impacts
excessive
and
repeated
pesticide
use.
Therefore,
this
study
evaluates
long-term
propachlor
ethanolic
sulfonic
acid
(PROP-ESA)
after
10
(T1)
20
(T2)
days
at
environmental
level
3.5
μg.L−1
(E1)
its
10x
fold
multiply
35
(E2)
model
organism
Mytilus
galloprovincialis.
To
end,
PROP-ESA
usually
showed
time-
dose-dependent
trend,
especially
amount
soft
mussel
tissue.
bioconcentration
factor
increased
from
T1
to
T2
both
exposure
groups
–
2.12
5.30
E1
2.32
5.48
E2.
Biochemical
haemolymph
profile
haemocyte
viability
were
not
affected
by
exposure.
In
addition,
digestive
gland
(DG)
cells
decreased
only
E2
compared
control
T1.
Moreover,
malondialdehyde
levels
gills,
DG,
superoxidase
dismutase
activity
oxidatively
modified
proteins
PROP-ESA.
Histopathological
observation
several
damages
gills
(e.g.,
vacuolation,
over-production
mucus,
loss
cilia)
DG
growing
trend
infiltrations,
alterations
tubules).
This
revealed
potential
risk
herbicide,
propachlor,
via
primary
metabolite
Bivalve
bioindicator
species
M.
Furthermore,
considering
possibility
biomagnification
effect,
most
prominent
threat
poses
ability
be
accumulated
edible
tissues.
future
research
toxicity
alone
or
their
mixtures
is
needed
gain
results
living
organisms.
Journal of Marine Science and Engineering,
Год журнала:
2020,
Номер
8(2), С. 73 - 73
Опубликована: Янв. 23, 2020
Deltamethrin
is
responsible
for
health
and
reproduction
problems
both
in
mammals
aquatic
organisms.
In
this
study,
zebrafish
adults
were
exposed
15
days
to
0.25,
0.5,
1,
2
μg
L−1
non-lethal
concentrations
of
deltamethrin,
knowing
that
used
worldwide
on
agricultural
crops.
We
investigated
the
chronic
effects
deltamethrin
gonads
by
histopathological
examination,
immunohistochemistry,
immunofluorescence
using
biomarkers
apoptosis
(anti-p53,
anti-H2A.XS139ph
antibodies,
TUNEL
assay),
oxidative
stress
(anti-Cox4i1
antibody)
proliferation
(anti-PCNA
antibody).
Among
changes,
apoptotic
response
was
elevated
ovary
testis
groups
as
it
seen
IHC
IF
p53,
H2A.XS139ph,
confirmed
assay.
These
observed
case
all
studied
compared
with
control
group.
Thereby,
gonadal
tissue
exhibited
an
up-regulated
activity
cell-death
signaling
markers,
while
marker
(PCNA)
increased
due
its
presence
not
only
primary
growth
cortical-alveolar
stage
follicles
but
also
atretic
follicles,
meanwhile
decreased
notably
testis.
Cox4i1,
a
mitochondrial
marker,
during
treatment,
probably
inhibited
overproduction
free
radicals
after
pesticide
exposure.
Ecotoxicology and Environmental Safety,
Год журнала:
2020,
Номер
203, С. 110980 - 110980
Опубликована: Июль 20, 2020
Pesticides
can
enter
aquatic
environments
potentially
affecting
non-target
organisms.
Unfortunately,
the
effects
of
such
substances
are
still
poorly
understood.
This
study
investigated
active
neonicotinoid
substance
thiacloprid
(TH)
and
commercial
product
Calypso
480
SC
(CA)
(active
compound
40.4%
TH)
on
Mytilus
galloprovincialis
after
short-term
exposure
to
sublethal
concentrations.
Mussels
were
tested
for
seven
days
0,
1,
5
10
mg
L-1
TH
10,
50
100
CA.
For
this
purpose,
several
parameters,
as
cell
viability
haemocytes
digestive
cells,
biochemical
haemolymph
features,
superoxide
dismutase
(SOD)
catalase
(CAT)
enzymatic
activity
gills
gland,
well
histology
tissues
analysed.
The
concentrations
both
lead
abatement
or
completely
stopping
byssal
fibres
creation.
Biochemical
analysis
showed
significant
changes
(P
<
0.01)
in
electrolytes
ions
(Cl-,
K+,
Na+,
Ca2+,
S-phosphor),
lactate
dehydrogenase
(LDH)
enzyme
glucose
concentration
following
substances.
TH-exposed
mussels
imbalance
0.05)
CAT
gland
gills.
CA
caused
decrease
SOD
tissues.
Results
histological
analyses
severe
damage
a
time-
concentration-dependent
manner.
provides
useful
information
about
acute
toxicity
insecticide
mussels.
Nevertheless,
considering
that
neonicotinoids
widely
used
very
important
species
marine
environment
human
consumption,
further
researches
needed
better
comprehend
potential
risk
posed
by
compounds
species.
Journal of Marine Science and Engineering,
Год журнала:
2020,
Номер
8(10), С. 801 - 801
Опубликована: Окт. 15, 2020
The
use
of
pesticides
in
agriculture
has
always
had
a
strong
impact
on
environmental
contamination.
Since
the
1990s,
neonicotinoids
have
grown
increasingly
more
popular,
targeting
specific
receptors
for
insects,
especially
bees,
which
is
why
some
been
banned.
Much
known
about
effects
they
but
very
little
effect
can
non-target
organisms.
Several
studies
shown
how
these
interact
negatively
with
normal
physiology
aquatic
For
genus
Mytilus,
even
though
did
not
show
an
interaction
receptors,
chronic
and
acute
exposure
to
them
causes
damage.
In
animals,
reduced
production
byssus,
alteration
antioxidant
systems
tissue
damage
found.
Therefore,
analysis
entire
ecosystem
pollutant
enters
great
importance
evaluating
any
possible
alterations.
Reviews in Aquaculture,
Год журнала:
2020,
Номер
12(4), С. 2511 - 2526
Опубликована: Июнь 18, 2020
Abstract
Aquatic
organisms
are
susceptible
throughout
their
lives
to
chemical
and
physical
stressors,
which
negatively
affect
health.
Various
aquatic
pollutants
derived
from
industrial
effluents,
overuse
of
some
agricultural
pesticides,
herbicides
insecticides
may
cause
devastating
toxicological
aspects
deteriorate
health
growth.
They
also
led
oxidative
stress
fish
due
the
stimulation
production
reactive
oxygen
species.
Therefore,
need
for
using
natural
antioxidants
be
used
as
feed
additives
is
great
importance
counteract
hazardous
responses.
The
use
phytochemicals,
characterized
by
substantial
antioxidative
effects,
has
been
raised.
Lycopene
principal
carotenoid
pigment
found
in
tomatoes
products,
vegetables
red
fruits.
Numerous
studies
have
recommended
lycopene
a
powerful
antioxidant
attenuate
responses
several
species
exposed
various
toxicants
or
any
other
conditions.
maintains
condition
enhancing
immune
This
review
article
aimed
elucidate
current
information
about
potential
dietary
its
capability
haemato‐immunological
alterations
resulted
environmental
stressors.
Additionally,
discusses
regarding
mode
action
assess
profits
that
would
aquaculture
industry.
International Journal of Molecular Sciences,
Год журнала:
2021,
Номер
22(17), С. 9591 - 9591
Опубликована: Сен. 4, 2021
In
this
paper,
we
review
the
effects
of
large-scale
neonicotinoid
contaminations
in
aquatic
environment
on
non-target
invertebrate
and
vertebrate
species.
These
species
are
fauna
widely
exposed
to
environmental
changes
chemical
accumulation
bodies
water.
Neonicotinoids
insecticides
that
target
nicotinic
type
acetylcholine
receptors
(nAChRs)
central
nervous
systems
(CNS)
considered
selective
neurotoxins
for
insects.
However,
studies
their
physiologic
impacts
interactions
with
limited.
researches
dedicated
exploring
toxic
outcomes
neonicotinoids,
relating
represent
a
minority
case
compared
For
species,
known
neonicotinoids
described
level
organismal,
behavioral,
genetic
toxicities.
Toxicological
were
reported
based
water,
temperature,
salinity
several
other
factors.
There
exists
knowledge
gap
relationship
between
toxicity
regulatory
risk
valuation.
It
has
been
general
observation
among
demonstrate
significant
an
extensive
variety
invertebrates.
Comprehensive
analysis
data
points
generalization
field-realistic
laboratory
exposures
could
result
different
or
non-comparable
results
some
cases.
Aquatic
invertebrates
perform
important
roles
balancing
healthy
ecosystem,
thus
rapid
screening
strategies
necessary
verify
toxicological
impacts.
So
far,
much
describing
field
tests
inadequate
many
cases,
obsolete.
Considering
current
literature,
addresses
information
gaps
spring
forward
policies,
avoiding
adverse
biological
ecological
range
which
might
further
impair
whole
web.
Ecotoxicology and Environmental Safety,
Год журнала:
2021,
Номер
216, С. 112227 - 112227
Опубликована: Апрель 11, 2021
Difenoconazole
(DIF),
a
common
broad-spectrum
triazole
fungicide,
is
associated
with
an
increased
risk
of
cardiovascular
diseases.
Unfortunately,
little
attention
has
been
paid
to
the
mechanisms
underlying
this
association.
In
study,
zebrafish
embryos
were
exposed
DIF
(0,
0.3,
0.6
and
1.2
mg/L)
from
4
96
h
post
fertilization
(hpf)
toxicity
was
evaluated.
Our
results
showed
that
decreased
hatching
rate,
survival
rate
heart
malformation
rate.
Cardiovascular
deformities
are
most
prominent,
including
pericardial
edema,
abnormal
cardiac
structure
disrupted
vascular
pattern
in
two
transgenic
models
(myl7:egfp
fli1:egfp).
exacerbated
oxidative
stress
by
via
accumulation
reactive
oxygen
species
(ROS)
inhibition
antioxidant
enzyme.
apoptosis
triggered
through
expression
p53,
bcl-2,
bax
caspase
9,
while
suppressed
transcription
key
genes
involved
calcium
signaling
muscle
contraction.
These
adverse
outcomes
restored
N-acetyl-L-cysteine
(NAC),
indicating
played
crucial
role
DIF-induced
caused
Taken
together,
study
revealed
provided
novel
insights
into
strategies
mitigate
its
toxicity.
