In
this
study,
we
compared
a
wide
range
of
cell-based
bioassays
to
the
use
chemical
analysis
followed
by
exposure-activity
ratio
(EAR)
and
Toxicological
Prioritization
index
(ToxPi)
for
prioritizing
chemicals,
sites,
hazard
concerns
in
water
samples.
Surface
samples
were
collected
from
nine
sites
three
Central
Pennsylvania
streams
analyzed
targeted
list
compounds
emerging
concern
(CECs),
including
pesticides,
personal
care
products,
pharmaceuticals.
Cell-based
reporter
assays
evaluated
human
zebrafish
molecular
initiating
events
(MIEs)
endocrine
metabolic
disruption,
altered
lipid
metabolism,
oxidative
stress.
Bioassays
showed
that
29
out
40
had
at
least
one
site
with
activity
over
limit
detection.
The
receptors
exhibited
highest
number
above
effect-based
trigger
(EBT)
values
would
be
expected
cause
toxicity
Aryl
hydrocarbon
receptor
(AhR,
zebrafish),
Pregnane
X
Receptor
(PXR),
Estrogen
Receptor-beta
(ERB),
Androgen
(AR).
Characterizing
collection
their
bioactivity
aligned
closely
stream
which
collected,
Warriors
Mark
Run,
Halfmoon,
Spruce
Run
more
similar
than
other
streams.
sum
all
EARs
each
indicated
pharmaceutical
Carbamazepine
pesticides
Carbaryl
Atrazine
posed
greatest
concern.
However,
predicted
prioritization
based
on
individual
calculated
EAR
different
those
measured
bioassay,
indicating
biologically
active
chemicals
are
present
not
included
analytes.
Taken
together,
these
data
show
beneficial
whereas
mechanism-based
inclusive
known
as
well
unknown
contaminants
thus
overall
quality
prioritization.
The Science of The Total Environment,
Год журнала:
2023,
Номер
868, С. 161376 - 161376
Опубликована: Янв. 6, 2023
Disinfection
commonly
follows
conventional
treatments
in
wastewater
treatment
and
remediation
plants
aiming
at
reducing
the
presence
of
pathogens.
However,
so
called
"micropollutants"
has
emerged
as
a
serious
concern,
therefore
developing
tertiary
that
are
not
only
able
to
remove
pathogens
but
also
degrade
micropollutants
is
worth
investigating.
Nowadays,
UV-C
photo-degradation
processes
widely
used
for
disinfection
due
their
simplicity
easy
operation;
additionally,
they
have
shown
potential
removal
contaminants
emerging
concern.
Conventional
mercury
lamps
being
replaced
by
light-emitting
diodes
(LEDs)
avoid
use
toxic
can
be
switched
on
off
with
no
effect
lamp
lifetime.
This
work
aims
comparatively
evaluate
performance
several
technologies
two
targeted
micropollutants,
pharmaceutical
dexamethasone
(DXMT)
herbicide
S-metolachlor
(MTLC),
using
UV
irradiation
doses
typical
processes.
To
this
end,
technical
UV-A/UV-C
photolysis,
photocatalysis,
UV-C/H2O2
UV-C/NaOCl
been
compared.
The
influence
operating
conditions
such
initial
concentration
pollutants
(3
mg
L-1
-
30
L-1,
concentrations
found
membrane
or
adsorption
steps),
pH
(3-10),
water
matrix
(WWTP
secondary
effluent,
ultrapure
water)
degradation
efficiency
studied.
economic
evaluation
terms
electricity
chemicals
consumption
carbon
footprint
evaluated.
photolysis
photocatalysis
appear
most
suitable
DXMT
MTLC,
respectively,
kinetics
(1.53·10-1
min-1
1.96·10-2
MTLC),
(1
€
m-3
32
MTLC)
environmental
indicators
(0.5
g-CO2
223.1
MTLC).
Current Opinion in Environmental Science & Health,
Год журнала:
2023,
Номер
35, С. 100495 - 100495
Опубликована: Авг. 3, 2023
Currently,
there
are
more
than
350,000
chemicals
in
use,
while
their
ecological
effects
not
fully
understood.
In
this
review,
we
focus
on
pesticides,
pharmaceuticals,
and
personal
care
products
discuss
potential
impact
aquatic
biodiversity
ecosystem
functions.
We
critically
reflect
strategies
to
reduce
environmental
release
mitigate
effects.
Various
mitigation
available
contaminant
concentrations
surface
waters,
but
efficiency
varies
under
the
current
procedures.
Intervening
at
start
of
chemicals'
life
cycles
or
reducing
diversity
production
amounts
holds
promise
for
water
exposure.
This
approach
could
facilitate
appropriate
risk
assessments
each
authorized
chemical.
