Pleurotus ostreatus polysaccharide-mediated modulation of skin damage caused by microcystin-LR in tadpoles DOI
Yilin Shu, Hui Wang, Huiling Jiang

и другие.

Environmental Pollution, Год журнала: 2024, Номер 345, С. 123440 - 123440

Опубликована: Янв. 28, 2024

Язык: Английский

A review and assessment of cyanobacterial toxins as cardiovascular health hazards DOI Open Access
Zorica Svirčev, Liang Chen,

Kinga Sántha

и другие.

Archives of Toxicology, Год журнала: 2022, Номер 96(11), С. 2829 - 2863

Опубликована: Авг. 23, 2022

Язык: Английский

Процитировано

29

Aging process does not necessarily enhance the toxicity of polystyrene microplastics to Microcystis aeruginosa DOI
Di Wu, Lin Deng, Ting Wang

и другие.

The Science of The Total Environment, Год журнала: 2023, Номер 882, С. 163608 - 163608

Опубликована: Апрель 20, 2023

Язык: Английский

Процитировано

22

Co-Occurrence of Taste and Odor Compounds and Cyanotoxins in Cyanobacterial Blooms: Emerging Risks to Human Health? DOI Creative Commons
Maura Manganelli, Emanuela Testai, Zakaria Tazart

и другие.

Microorganisms, Год журнала: 2023, Номер 11(4), С. 872 - 872

Опубликована: Март 28, 2023

Cyanobacteria commonly form large blooms in waterbodies; they can produce cyanotoxins, with toxic effects on humans and animals, volatile compounds, causing bad tastes odors (T&O) at naturally occurring low concentrations. Notwithstanding the amount of literature either cyanotoxins or T&O, no review has focused them same time. The present critically evaluates recent T&O compounds (geosmin, 2-methylisoborneol, β-ionone β-cyclocitral) to identify research gaps harmful exposure animals both metabolite classes. production be due common different cyanobacterial species/strains, additional possibility by non-cyanobacterial species. few environmental studies co-occurrence these two groups metabolites are not sufficient understand if how co-vary, influence each other, perhaps stimulating cyanotoxin production. Therefore, T&Os cannot reliably serve as early warning surrogates for cyanotoxins. scarce data toxicity seem indicate a health risk (but inhalation β-cyclocitral deserves more study). However, available combined mixtures combinations compounds; therefore, whether is issue remains an open question.

Язык: Английский

Процитировано

19

Microcystins Exposure Associated with Blood Lipid Profiles and Dyslipidemia: A Cross-Sectional Study in Hunan Province, China DOI Creative Commons

Shuidong Feng,

Meng-Yue Cao,

Peng Tang

и другие.

Toxins, Год журнала: 2023, Номер 15(4), С. 293 - 293

Опубликована: Апрель 18, 2023

Increasing evidence from experimental research suggests that exposure to microcystins (MCs) may induce lipid metabolism disorder. However, population-based epidemiological studies of the association between MCs and risk dyslipidemia are lacking. Therefore, we conducted a cross-sectional study involving 720 participants in Hunan Province, China, evaluated effects on blood lipids. After adjusting related metals, used binary logistic regression multiple linear models examine associations among serum concentration, lipids (triglyceride (TG), total cholesterol (TC), high-density lipoprotein (HDL-C) low-density (LDL-C)). Moreover, additive model was explore interaction metals. Compared lowest quartile exposure, [odds ratios (OR) = 2.27, 95% confidence interval (CI): 1.46, 3.53] hyperTG (OR 3.01, CI: 1.79, 5.05) highest significantly increased, showed dose-response relationships. were positively associated with TG level (percent change, 9.43%; 3.53%, 15.67%) negatively HDL-C -3.53%; -5.70%, -2.10%). In addition, an antagonistic effect Zn also reported [relative excess due (RERI) -1.81 (95% -3.56, -0.05)], attributable proportion reduced antagonism these two exposures 83% -1.66, -0.005). Our first indicated is independent factor for manner.

Язык: Английский

Процитировано

19

The impact of ammonia and microcystin-LR on neurobehavior and glutamate/gamma-aminobutyric acid balance in female zebrafish (Danio rerio): ROS and inflammation as key pathways DOI

Ya He,

Kang Ou-Yang,

Hui Yang

и другие.

The Science of The Total Environment, Год журнала: 2024, Номер 920, С. 170914 - 170914

Опубликована: Фев. 12, 2024

Язык: Английский

Процитировано

8

Mechanisms of parental co-exposure to polystyrene nanoplastics and microcystin-LR aggravated hatching inhibition of zebrafish offspring DOI
Qin Wu, Guangyu Li,

Tangbin Huo

и другие.

The Science of The Total Environment, Год журнала: 2021, Номер 774, С. 145766 - 145766

Опубликована: Фев. 11, 2021

Язык: Английский

Процитировано

38

Microcystin-LR in Primary Liver Cancers: An Overview DOI Creative Commons
Shen Gu,

Mingxuemei Jiang,

Bo Zhang

и другие.

Toxins, Год журнала: 2022, Номер 14(10), С. 715 - 715

Опубликована: Окт. 20, 2022

The cyanobacterial blooms produced by eutrophic water bodies have become a serious environmental issue around the world. After cellular lysing or algaecide treatment, microcystins (MCs), which are regarded as most frequently encountered toxins in fresh water, released into water. Among all variants of MCs, MC-LR has been widely studied due to its severe hepatotoxicity. Since 1992, various studies identified important roles origin and progression primary liver cancers (PLCs), although few reviews focused on it. Therefore, this review aims summarize major achievements shortcomings observed past years. Based available literature, mechanisms how induces promotes PLCs elucidated review. This enhance our understanding role that plays provides rational approach for future applications.

Язык: Английский

Процитировано

28

Acute exposure to microcystins affects hypothalamic-pituitary axes of male rats DOI
Ting Shi, Linlin Xu, Liang Chen

и другие.

Environmental Pollution, Год журнала: 2022, Номер 318, С. 120843 - 120843

Опубликована: Дек. 9, 2022

Язык: Английский

Процитировано

25

The mechanisms of microcystin-LR-induced genotoxicity and neurotoxicity in fish and mammals: Bibliometric analysis and meta-analysis DOI
Huixia Zhang, Ping Xie

The Science of The Total Environment, Год журнала: 2023, Номер 905, С. 167018 - 167018

Опубликована: Сен. 14, 2023

Язык: Английский

Процитировано

15

Gut Microbiota of Freshwater Gastropod (Bellamya aeruginosa) Assist the Adaptation of Host to Toxic Cyanobacterial Stress DOI Creative Commons
Hongfang Liu, Xianming Yang, Wen Yang

и другие.

Toxins, Год журнала: 2023, Номер 15(4), С. 252 - 252

Опубликована: Март 29, 2023

Gut microbes play a critical role in helping hosts adapt to external environmental changes and are becoming an important phenotype for evaluating the response of aquatic animals stresses. However, few studies have reported that gut after exposure gastropods bloom-forming cyanobacteria toxins. In this study, we investigated pattern potential intestinal flora freshwater gastropod Bellamya aeruginosa when exposed toxic non-toxic strains Microcystis aeruginosa, respectively. Results showed composition toxin-producing group (T group) changed significantly over time. The concentration microcystins (MCs) hepatopancreas tissue decreased from 2.41 ± 0.12 on day 7 1.43 0.10 μg·g−1 dry weight 14 T group. abundance cellulase-producing bacteria (Acinetobacter) was higher (NT than 14, whereas relative MC-degrading (Pseudomonas Ralstonia) NT 14. addition, co-occurrence networks were more complex at Some genera identified as key nodes, such Acinetobacter, Pseudomonas, Ralstonia, different patterns variation network. Network nodes clustered Acinetobacter increased interactions between Pseudomonas Ralstonia other almost positive correlations D7T negative D14T These results suggested these not only ability improve host resistance cyanobacterial stress by themselves, but they can also further assist adaptation regulating interaction within community. This study provides useful information understanding reveals underlying tolerance mechanisms B. cyanobacteria.

Язык: Английский

Процитировано

13