Nutritional Management of Thyroiditis of Hashimoto

International Journal of Molecular Sciences, Год журнала: 2022, Номер 23(9), С. 5144 - 5144

Опубликована: Май 5, 2022

Since the thyroid gland is one of organs most affected by autoimmune processes, many patients with thyroiditis Hashimoto (TH) seek medical advice on lifestyle variance and dietary modifications to improve maintain their hyroid function. In this review, we aim present discuss some challenges associated nutritional management TH, focusing environmental deficits, inflammatory toxic nutrients, cyanotoxins, etc. We relationships among different diets, chronic inflammation, microbiota, impact development exacerbation TH in detail. share novel insights into role vitamin D melatonin for preserving function during inflammation predisposed subjects. A comprehensive overview provided anti-inflammatory nutrients ecological including foods cleansing detoxification, which represent strategies prevent relapses achieve overall improvement life quality. conclusion, data from biomedical clinical studies provide evidence that an appropriate lighting regimen could significantly reduce reactivity autoantibodies TH. Compliance guidelines may help need medicines.

Язык: Английский

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Freshwater Cyanobacterial Toxins, Cyanopeptides and Neurodegenerative Diseases

Toxins, Год журнала: 2023, Номер 15(3), С. 233 - 233

Опубликована: Март 21, 2023

Cyanobacteria produce a wide range of structurally diverse cyanotoxins and bioactive cyanopeptides in freshwater, marine, terrestrial ecosystems. The health significance these metabolites, which include genotoxic- neurotoxic agents, is confirmed by continued associations between the occurrence animal human acute toxic events and, long term, cyanobacteria neurodegenerative diseases. Major mechanisms related to neurotoxicity compounds (1) blocking key proteins channels; (2) inhibition essential enzymes mammalian cells such as protein phosphatases phosphoprotein well new molecular targets toll-like receptors 4 8. One widely discussed implicated includes misincorporation cyanobacterial non-proteogenic amino acids. Recent research provides evidence that non-proteinogenic acid BMAA produced have multiple effects on translation process bypasses proof-reading ability aminoacyl-tRNA-synthetase. Aberrant generated non-canonical may be factor neuronal death neurodegeneration. We hypothesize production acids more general mechanism, leading mistranslation, affecting homeostasis, targeting mitochondria eukaryotic cells. It can evolutionarily ancient initially developed control phytoplankton communities during algal blooms. Outcompeting gut symbiotic microorganisms lead dysbiosis, increased permeability, shift blood-brain-barrier functionality, eventually, mitochondrial dysfunction high-energy demanding neurons. A better understanding interaction metabolism nervous system will crucial target or prevent

Язык: Английский

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Cyanotoxins, biosynthetic gene clusters, and factors modulating cyanotoxin biosynthesis

World Journal of Microbiology and Biotechnology, Год журнала: 2023, Номер 39(9)

Опубликована: Июль 3, 2023

Язык: Английский

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A review and assessment of cyanobacterial toxins as cardiovascular health hazards

Archives of Toxicology, Год журнала: 2022, Номер 96(11), С. 2829 - 2863

Опубликована: Авг. 23, 2022

Язык: Английский

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Acute exposure to microcystins affects hypothalamic-pituitary axes of male rats

Environmental Pollution, Год журнала: 2022, Номер 318, С. 120843 - 120843

Опубликована: Дек. 9, 2022

Язык: Английский

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Nodding syndrome: A role for environmental biotoxins that dysregulate MECP2 expression?

Journal of the Neurological Sciences, Год журнала: 2024, Номер 462, С. 123077 - 123077

Опубликована: Июнь 2, 2024

Язык: Английский

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Prenatal exposure to bisphenol S and bisphenol A differentially affects male reproductive system in the adult offspring

Food and Chemical Toxicology, Год журнала: 2022, Номер 167, С. 113292 - 113292

Опубликована: Июль 13, 2022

Язык: Английский

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A new identity of microcystins: Environmental endocrine disruptors? An evidence-based review

The Science of The Total Environment, Год журнала: 2022, Номер 851, С. 158262 - 158262

Опубликована: Авг. 24, 2022

Язык: Английский

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Effect of estrogen on myocardial ischemia–reperfusion injury in male and female rats and related mechanism

Steroids, Год журнала: 2025, Номер unknown, С. 109561 - 109561

Опубликована: Янв. 1, 2025

Язык: Английский

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Melamine-induced adrenal structural and functional alterations and the contribution of morin to the adrenal repair in Wistar rats

Tissue and Cell, Год журнала: 2025, Номер 95, С. 102826 - 102826

Опубликована: Март 1, 2025

Язык: Английский

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