Feeding crocin ameliorate cognitive dysfunction, oxidative stress and neuroinflammation induced by unpredictable chronic mild stress in rats DOI
Ali Abbaszade‐Cheragheali,

Samaneh Kakhki,

Seyed Reza Khatibi

et al.

Inflammopharmacology, Journal Year: 2023, Volume and Issue: 31(4), P. 2079 - 2090

Published: June 1, 2023

Language: Английский

Nutritional Management of Thyroiditis of Hashimoto DOI Open Access

Yana Danailova,

Tsvetelina Velikova, Georgi Nikolaev

et al.

International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(9), P. 5144 - 5144

Published: May 5, 2022

Since the thyroid gland is one of organs most affected by autoimmune processes, many patients with thyroiditis Hashimoto (TH) seek medical advice on lifestyle variance and dietary modifications to improve maintain their hyroid function. In this review, we aim present discuss some challenges associated nutritional management TH, focusing environmental deficits, inflammatory toxic nutrients, cyanotoxins, etc. We relationships among different diets, chronic inflammation, microbiota, impact development exacerbation TH in detail. share novel insights into role vitamin D melatonin for preserving function during inflammation predisposed subjects. A comprehensive overview provided anti-inflammatory nutrients ecological including foods cleansing detoxification, which represent strategies prevent relapses achieve overall improvement life quality. conclusion, data from biomedical clinical studies provide evidence that an appropriate lighting regimen could significantly reduce reactivity autoantibodies TH. Compliance guidelines may help need medicines.

Language: Английский

Citations

41
Freshwater Cyanobacterial Toxins, Cyanopeptides and Neurodegenerative Diseases DOI Creative Commons
Galina Nugumanova, Eugene D. Ponomarev, Sholpan Askarova

et al.

Toxins, Journal Year: 2023, Volume and Issue: 15(3), P. 233 - 233

Published: March 21, 2023

Cyanobacteria produce a wide range of structurally diverse cyanotoxins and bioactive cyanopeptides in freshwater, marine, terrestrial ecosystems. The health significance these metabolites, which include genotoxic- neurotoxic agents, is confirmed by continued associations between the occurrence animal human acute toxic events and, long term, cyanobacteria neurodegenerative diseases. Major mechanisms related to neurotoxicity compounds (1) blocking key proteins channels; (2) inhibition essential enzymes mammalian cells such as protein phosphatases phosphoprotein well new molecular targets toll-like receptors 4 8. One widely discussed implicated includes misincorporation cyanobacterial non-proteogenic amino acids. Recent research provides evidence that non-proteinogenic acid BMAA produced have multiple effects on translation process bypasses proof-reading ability aminoacyl-tRNA-synthetase. Aberrant generated non-canonical may be factor neuronal death neurodegeneration. We hypothesize production acids more general mechanism, leading mistranslation, affecting homeostasis, targeting mitochondria eukaryotic cells. It can evolutionarily ancient initially developed control phytoplankton communities during algal blooms. Outcompeting gut symbiotic microorganisms lead dysbiosis, increased permeability, shift blood-brain-barrier functionality, eventually, mitochondrial dysfunction high-energy demanding neurons. A better understanding interaction metabolism nervous system will crucial target or prevent

Language: Английский

Citations

23
Cyanotoxins, biosynthetic gene clusters, and factors modulating cyanotoxin biosynthesis DOI

Fahim Bashir,

Arif Bashir,

Noureddine Bouaı̈cha

et al.

World Journal of Microbiology and Biotechnology, Journal Year: 2023, Volume and Issue: 39(9)

Published: July 3, 2023

Language: Английский

Citations

23
A review and assessment of cyanobacterial toxins as cardiovascular health hazards DOI Open Access
Zorica Svirčev, Liang Chen,

Kinga Sántha

et al.

Archives of Toxicology, Journal Year: 2022, Volume and Issue: 96(11), P. 2829 - 2863

Published: Aug. 23, 2022

Language: Английский

Citations

26
Acute exposure to microcystins affects hypothalamic-pituitary axes of male rats DOI
Ting Shi, Linlin Xu, Liang Chen

et al.

Environmental Pollution, Journal Year: 2022, Volume and Issue: 318, P. 120843 - 120843

Published: Dec. 9, 2022

Language: Английский

Citations

23
Nodding syndrome: A role for environmental biotoxins that dysregulate MECP2 expression? DOI Creative Commons
Peter S. Spencer, Raquel Valdes Angues,

Valerie S. Palmer

et al.

Journal of the Neurological Sciences, Journal Year: 2024, Volume and Issue: 462, P. 123077 - 123077

Published: June 2, 2024

Language: Английский

Citations

5
Prenatal exposure to bisphenol S and bisphenol A differentially affects male reproductive system in the adult offspring DOI

Archana Molangiri,

Saikanth Varma,

M. Satyavani

et al.

Food and Chemical Toxicology, Journal Year: 2022, Volume and Issue: 167, P. 113292 - 113292

Published: July 13, 2022

Language: Английский

Citations

19
A new identity of microcystins: Environmental endocrine disruptors? An evidence-based review DOI
Shiyu Zhang, Haohao Liu, Xingde Du

et al.

The Science of The Total Environment, Journal Year: 2022, Volume and Issue: 851, P. 158262 - 158262

Published: Aug. 24, 2022

Language: Английский

Citations

19
Effect of estrogen on myocardial ischemia–reperfusion injury in male and female rats and related mechanism DOI
Si‐Chong Chen, Lijuan Yang,

Jianyao Xue

et al.

Steroids, Journal Year: 2025, Volume and Issue: unknown, P. 109561 - 109561

Published: Jan. 1, 2025

Language: Английский

Citations

0
Melamine-induced adrenal structural and functional alterations and the contribution of morin to the adrenal repair in Wistar rats DOI

Alshaymaa M. Abdelmenem,

Ezat A. Mersal, Ahmed A. Morsi

et al.

Tissue and Cell, Journal Year: 2025, Volume and Issue: 95, P. 102826 - 102826

Published: March 1, 2025

Language: Английский

Citations

0