Journal of Personalized Medicine,
Год журнала:
2023,
Номер
13(12), С. 1659 - 1659
Опубликована: Ноя. 28, 2023
The
current
treatment
for
the
autoimmune
disease
of
hypothyroidism
(AIDH)
is
based
on
pharmacotherapy
with
levothyroxine.
A
non-pharmacological
supplementary
element
therapy
could
be
implementation
an
individualized
balanced
diet
and
probiotics.
Lactiplantibacillus
plantarum
299v
(Lp299v),
its
anti-inflammatory
effects,
may
also
support
therapy.
However,
number
studies
personalized
dietary
interventions
probiotics
in
AIDH
limited,
no
clear
conclusions
can
drawn
from
results
so
far.
Therefore,
this
trial
will
analyze
effect
Lp299v
supplementation
conjunction
nutrition
education
quality
life
nutritional
status
patients
Hashimoto's.
Methods:
This
double-blind,
12-week
intervention
study
include
100
female
AIDH.
They
divided
into
two
groups:
(1)
individual
+
(2)
placebo.
Before
after
intervention,
selected
elements
diet,
eating
behavior,
life,
(anthropometric
parameters,
body
composition),
blood
pressure,
anti-TPO
(antibodies
against
thyroid
peroxidase)
titer
assessed.
Hypothesis:
It
expected
that
provide
deeper
knowledge
validity
using
proper
principles
Specifically,
impact
subjective
assessment
state
health
Nutrients,
Год журнала:
2022,
Номер
14(19), С. 3934 - 3934
Опубликована: Сен. 22, 2022
Melatonin
has
become
a
popular
dietary
supplement,
most
known
as
chronobiotic,
and
for
establishing
healthy
sleep.
Research
over
the
last
decade
into
cancer,
Alzheimer’s
disease,
multiple
sclerosis,
fertility,
PCOS,
many
other
conditions,
combined
with
COVID-19
pandemic,
led
to
greater
awareness
of
melatonin
because
its
ability
act
potent
antioxidant,
immune-active
agent,
mitochondrial
regulator.
There
are
distinct
similarities
between
vitamin
D
in
depth
breadth
their
impact
on
health.
Both
hormones,
affect
systems
through
immune-modulating,
anti-inflammatory
functions,
found
skin,
responsive
sunlight
darkness.
In
fact,
there
may
be
widespread
concern
about
deficiency
“sunlight
deficiency”
reduced
secretion
result
“darkness
from
overexposure
artificial
blue
light.
The
trend
toward
use
supplements
resulted
safety,
especially
higher
doses,
long-term
use,
application
certain
populations
(e.g.,
children).
This
review
aims
evaluate
recent
data
melatonin’s
mechanisms,
clinical
uses
beyond
sleep,
safety
concerns,
thorough
summary
therapeutic
considerations
concerning
supplementation,
including
different
formats
available
(animal,
synthetic,
phytomelatonin),
dosing,
timing,
contraindications,
nutrient
combinations.
Nutrients,
Год журнала:
2023,
Номер
15(20), С. 4486 - 4486
Опубликована: Окт. 23, 2023
Resveratrol
is
a
stilbenoid
from
red
grapes
that
possesses
strong
antioxidant
activity.
has
been
shown
to
have
anticancer
activity,
making
it
promising
drug
for
the
treatment
and
prevention
of
numerous
cancers.
Several
in
vitro
vivo
investigations
validated
resveratrol’s
capabilities,
demonstrating
its
ability
block
all
steps
carcinogenesis
(such
as
initiation,
promotion,
progression).
Additionally,
resveratrol
found
auxiliary
pharmacological
effects
such
anti-inflammatory,
cardioprotective,
neuroprotective
Despite
properties,
several
obstacles,
poor
solubility
bioavailability,
well
adverse
effects,
continue
be
key
obstacles
development.
This
review
critically
evaluates
clinical
trials
date
aims
develop
framework
into
clinically
viable
drug.
Nutrients,
Год журнала:
2023,
Номер
15(4), С. 1041 - 1041
Опубликована: Фев. 20, 2023
Diet
can
be
a
complementary
treatment
for
Hashimoto’s
disease
by
affecting
thyroid
function
and
anti-inflammatory
properties.
It
is
still
unclear
which
dietary
strategy
would
the
most
beneficial.
The
aim
of
this
systematic
review
to
examine
all
data
currently
available
in
literature
on
effects
nutritional
intervention
biochemical
parameters
(anti-thyroid
antibody
hormones
levels)
characteristic
symptoms
course
thyroiditis.
This
was
prepared
based
PRISMA
guidelines.
Articles
PubMed
Scopus
databases
published
up
November
2022
were
searched.
As
result
selection,
out
1350
publications,
9
included
further
analysis.
interventions
following:
elimination
gluten
(3
articles)
or
lactose
(1
article),
energy
restriction
with
without
excluding
selected
foods
(n
=
2),
consumption
Nigella
sativa
iodine
1).
duration
ranged
from
21
days
12
months
individuals
various
function.
Of
nine
studies,
three
studies
female
only.
An
improvement
observed
during
an
deficit
after
ingredients
(e.g.,
gluten,
lactose,
goitrogens),
as
well
sativa.
These
improved
levels
against
peroxidase
(anti-TPO),
(thyrotropin)
TSH,
free
thyroxine
(fT4).
No
seen
iodine-restricted
diet.
Varied
outcomes
analyzed
may
due
heterogeneous
condition,
high
variability
between
patients,
differences
habitual
intake
critical
nutrients
iodine,
selenium,
iron)
different
populations.
Therefore,
there
great
need
experimental
determine
whether
any
are
beneficial
disease.
Antioxidants,
Год журнала:
2023,
Номер
12(5), С. 1126 - 1126
Опубликована: Май 19, 2023
This
review
is
focused
on
the
mechanisms
that
regulate
health,
disease
and
aging
redox
status,
signal
pathways
counteract
oxidative
reductive
stress,
role
of
food
components
additives
with
antioxidant
properties
(curcumin,
polyphenols,
vitamins,
carotenoids,
flavonoids,
etc.),
hormones
irisin
melatonin
in
homeostasis
animal
human
cells.
The
correlations
between
deviation
from
optimal
conditions
inflammation,
allergic,
autoimmune
responses
are
discussed.
Special
attention
given
to
vascular
system,
kidney,
liver
brain
stress
processes.
hydrogen
peroxide
as
an
intracellular
paracrine
molecule
also
reviewed.
cyanotoxins
β-N-methylamino-l-alanine
(BMAA),
cylindrospermopsin,
microcystins
nodularins
introduced
potentially
dangerous
environment
pro-oxidants.
Frontiers in Immunology,
Год журнала:
2023,
Номер
14
Опубликована: Июль 31, 2023
In
recent
years,
there
has
been
a
significant
increase
in
the
concomitant
incidence
of
Hashimoto’s
thyroiditis
(HT)
and
polycystic
ovary
syndrome
(PCOS),
both
terms
incidence,
etiology,
clinical
consequences.
PCOS
patients
suffering
from
autoimmune
thyroid
diseases
show
insulin
resistance,
impaired
glucose
tolerance,
weight
gain,
metabolic
reproductive
complications.
Studies
have
shown
that
chronic
stress
its
consequence,
i.e.
oxidative
stress,
play
an
important
role
pathomechanism
disorders.
It
also
long-term
exposure
to
triggers
biological
mechanisms,
particular
related
regulation
inflammatory
cascade,
which
plays
key
diseases.
The
paper
is
review
literature
on
immune
processes
pathogenesis
HT
PCOS.
addition,
source
knowledge
about
treatment
these
diseases,
use
antioxidants
therapeutic
management.
Medicina,
Год журнала:
2024,
Номер
60(9), С. 1454 - 1454
Опубликована: Сен. 5, 2024
The
available
research
suggests
that
dietary
patterns
with
high
inflammatory
potential,
as
indicated
by
a
DII
score,
may
exacerbate
inflammation
and
potentially
influence
thyroid
function.
Therefore,
the
aim
of
this
study
was
to
investigate
associations
between
potential
diet
function
in
adults
Hashimoto's
thyroiditis
(HT).
Biomedicines,
Год журнала:
2024,
Номер
12(4), С. 911 - 911
Опубликована: Апрель 19, 2024
Nutrition
management
is
fundamental
for
children
with
chronic
kidney
disease
(CKD).
Fluid
balance
and
low-protein
low-sodium
diets
are
the
more
stressed
fields
from
a
nutritional
point
of
view.
At
same
time,
role
micronutrients
often
underestimated.
Starting
causes
that
could
lead
to
potential
micronutrient
deficiencies
in
these
patients,
this
review
considers
all
be
administered
CKD
improve
prognosis
disease.
Nutrients,
Год журнала:
2024,
Номер
16(11), С. 1694 - 1694
Опубликована: Май 29, 2024
Hashimoto’s
thyroiditis
(HT)
is
the
leading
cause
of
hypothyroidism,
affecting
mainly
female
population.
Many
patients
with
HT
have
metabolic
disorders
and
nutritional
deficiencies.
The
aim
this
study
was
to
evaluate
vitamin
D,
A,
E,
B2,
B6
concentrations,
thyroid
function,
profile,
anthropometric
parameters
thyroiditis.
In
81
(study
group),
A
B2
concentrations
were
significantly
lower
than
in
34
healthy
women
(control
group).
No
differences
noted
between
groups.
Moreover,
had
similar
parameters,
lipid
profiles,
glucose
insulin
compared
controls.
This
showed
some
relationships
or
biochemical
profiles
patients.
Among
others,
group,
concentration
D
positively
correlated
level
HDL
negatively
BMI,
total
fat
mass,
level,
which
influence
cardiovascular
risk.
results
indicate
that
should
be
routinely
tested
for
prevent
Further
studies
are
also
needed
on
role
vitamins
development
progression
presence
complications
