Frontiers in Public Health,
Год журнала:
2024,
Номер
12
Опубликована: Июль 23, 2024
Introduction
Seasonal
influenza
generally
represents
an
underestimated
public
health
problem
with
significant
socioeconomic
implications.
Monitoring
and
detecting
epidemics
are
important
tasks
that
require
integrated
strategies.
Wastewater-based
epidemiology
(WBE)
is
emerging
field
uses
wastewater
data
to
monitor
the
spread
of
disease
assess
a
community.
It
can
represent
integrative
surveillance
tool
for
better
understanding
prevention
strategies
in
health.
Methods
We
conducted
study
detected
presence
Influenza
virus
RNA
using
wastewater-based
approach.
Samples
were
collected
from
five
treatment
plants
different
municipalities,
serving
cumulative
population
555,673
Sicilian
inhabitants
Italy.
used
RT-qPCR
test
compare
combined
weekly
average
A
B
viral
samples
incidence
Influenza-like
illness
(ILI)
obtained
Italian
national
system.
also
compared
number
positive
swabs
loads
wastewater.
Our
investigated
189
samples.
Results
Cumulative
ILI
cases
substantially
overlapped
load
trends
similar
rise
population.
Therefore,
confirmed
co-circulation
viruses
during
season
2022/2023,
trend
reported
clinically
cases.
Conclusion
does
not
replace
traditional
epidemiological
methods,
such
as
laboratory
testing
infected
individuals.
However,
it
be
valuable
complement
obtaining
additional
information
on
preventing
its
spread.
Current Pollution Reports,
Год журнала:
2024,
Номер
10(2), С. 312 - 325
Опубликована: Май 21, 2024
Abstract
Purpose
of
Review
This
study
aims
to
review
recent
literature
reporting
wastewater-based
surveillance
(WBS)
the
monkeypox
virus
(MPXV)
with
a
major
focus
on
sample
collection,
processing,
and
public
health
safety
issues.
Recent
Findings
Various
studies
revealed
presence
MPXV
genetic
markers
in
sewage,
wastewater
treatment
plants,
drainage
systems
hospitals
multiple
countries.
Summary
Mpox
(formally
monkeypox)
has
been
identified
more
than
hundred
countries,
confirming
at
least
93,937
cases
from
06
May
2022
03
February
2024.
The
MPXV,
causative
agent
for
mpox,
is
zoonotic
having
genome
DNA.
Major
symptoms
disease
are
rash,
fever,
headache,
chills
lymph
pain.
It
about
10%
case
fatality
rate,
without
any
approved
vaccine,
but
researchers
investigating
development
therapeutic
vaccines.
DNA
signature
long
reported
urine,
stool,
saliva,
semen,
spit
samples
clinical
patients,
make
feasible
tracking
wastewater.
Furthermore,
have
environmental
samples.
As
possible
hosts
(e.g.,
small
mammals
rodents),
their
detection
might
indicate
circulation
including
non-human
hosts.
persistence
infective
particles
ambient
environment
not
fully
investigated.
Also,
risks
transmission
through
contaminated
milieu
unknown.
WBS
can
be
an
effective
tool
identifying
hotspots
trends
communities.
Graphical
Environmental Research,
Год журнала:
2022,
Номер
210, С. 112967 - 112967
Опубликована: Фев. 18, 2022
Wastewater-based
epidemiology
offers
a
time-
and
cost-effective
way
to
monitor
SARS-CoV-2
spread
in
communities
therefore
represents
complement
clinical
testing.
WBE
applicability
has
been
demonstrated
number
of
cases
over
short-term
periods
as
method
for
tracking
the
prevalence
an
early-warning
tool
predicting
outbreaks
population.
This
study
reports
viral
loads
from
wastewater
treatment
plants
(WWTPs)
hospitals
6-month
period
(June
December
2020).
Results
show
that
overall
range
load
positive
tested
samples
was
between
1.2
×
10
Environmental Research,
Год журнала:
2023,
Номер
231, С. 115911 - 115911
Опубликована: Апрель 25, 2023
Tuberculosis
(TB)
remains
a
persistent
challenge
to
public
health
and
presents
substantial
menace,
especially
in
developing
nations
of
sub-Saharan
Africa.
It
exerts
considerable
strain
on
healthcare
systems
these
regions.
Effective
control
requires
reliable
surveillance,
which
can
be
improved
by
incorporating
environmental
data
alongside
clinical
data.
Molecular
advances
have
led
the
development
alternative
surveillance
methods,
such
as
wastewater-based
epidemiology.
This
studyinvestigated
presence,
concentration,
diversity
Mycobacterium
tuberculosis
complex,
cause
TB,
from
six
African
countries:
Ghana,
Nigeria,
Kenya,
Uganda,
Cameroon,
South
Samples
were
collected
wastewater
treatment
plants.
All
samples
found
contain
species
that
been
linked
TB
both
humans
animals,
including
tuberculosis,
bovis,
africanum,
caprae,
at
varying
concentrations.
The
highest
median
concentration
was
reaching
up
4.7
Log
copies/ml
for
MTBC,
4.6
M.
3.4
africanum.
presence
africanum
outside
West
Africa
Africa,
Uganda
could
indicate
spread
pathogen.
study
underscores
usefulness
epidemiology
tracking
shows
even
treated
may
pathogens,
posing
potential
risks.
PLoS ONE,
Год журнала:
2024,
Номер
19(7), С. e0307364 - e0307364
Опубликована: Июль 18, 2024
Background
Wastewater-based
epidemiology
(WBE)
surveillance
has
been
proposed
as
an
early
warning
system
(EWS)
for
community
SARS-CoV-2
transmission.
However,
there
is
limited
data
from
low-and
middle-income
countries
(LMICs).
This
study
aimed
to
assess
the
ability
of
WBE
detect
in
formal
and
informal
environments
Indonesia
using
different
methods
sample
collection,
compare
with
patterns
clinical
cases
COVID-19
within
relevant
communities,
potential
be
used
EWS
outbreaks
a
community.
Materials
We
conducted
three
districts
Yogyakarta
province,
Indonesia,
over
eleven
months
(27
July
2021
7
January
2022
[Delta
wave];
18
3
June
[Omicron
wave]).
Water
samples
grab,
and/or
passive
sampling
soil
were
collected
either
weekly
or
fortnightly.
RNA
was
extracted
membrane
filters
processed
water
directly
soil.
Reverse-transcription
quantitative
real-time
polymerase
chain
reaction
(RT-qPCR)
performed
N
ORF1ab
genes.
Results
A
total
1,582
collected.
Detection
rates
wastewater
reflected
incidence
cases,
85%
at
peak
2%
end
Delta
wave
94%
11%
during
Omicron
wave.
2-week
lag
time
observed
between
detection
increasing
corresponding
Conclusion
effective
monitoring
served
system,
predicting
Frontiers in Public Health,
Год журнала:
2024,
Номер
12
Опубликована: Июль 23, 2024
Introduction
Seasonal
influenza
generally
represents
an
underestimated
public
health
problem
with
significant
socioeconomic
implications.
Monitoring
and
detecting
epidemics
are
important
tasks
that
require
integrated
strategies.
Wastewater-based
epidemiology
(WBE)
is
emerging
field
uses
wastewater
data
to
monitor
the
spread
of
disease
assess
a
community.
It
can
represent
integrative
surveillance
tool
for
better
understanding
prevention
strategies
in
health.
Methods
We
conducted
study
detected
presence
Influenza
virus
RNA
using
wastewater-based
approach.
Samples
were
collected
from
five
treatment
plants
different
municipalities,
serving
cumulative
population
555,673
Sicilian
inhabitants
Italy.
used
RT-qPCR
test
compare
combined
weekly
average
A
B
viral
samples
incidence
Influenza-like
illness
(ILI)
obtained
Italian
national
system.
also
compared
number
positive
swabs
loads
wastewater.
Our
investigated
189
samples.
Results
Cumulative
ILI
cases
substantially
overlapped
load
trends
similar
rise
population.
Therefore,
confirmed
co-circulation
viruses
during
season
2022/2023,
trend
reported
clinically
cases.
Conclusion
does
not
replace
traditional
epidemiological
methods,
such
as
laboratory
testing
infected
individuals.
However,
it
be
valuable
complement
obtaining
additional
information
on
preventing
its
spread.
