Detection of influenza virus in urban wastewater during the season 2022/2023 in Sicily, Italy DOI Creative Commons
Carmelo Massimo Maida, Walter Mazzucco,

Walter Priano

и другие.

Frontiers in Public Health, Год журнала: 2024, Номер 12

Опубликована: Июль 23, 2024

Introduction Seasonal influenza generally represents an underestimated public health problem with significant socioeconomic implications. Monitoring and detecting epidemics are important tasks that require integrated strategies. Wastewater-based epidemiology (WBE) is emerging field uses wastewater data to monitor the spread of disease assess a community. It can represent integrative surveillance tool for better understanding prevention strategies in health. Methods We conducted study detected presence Influenza virus RNA using wastewater-based approach. Samples were collected from five treatment plants different municipalities, serving cumulative population 555,673 Sicilian inhabitants Italy. used RT-qPCR test compare combined weekly average A B viral samples incidence Influenza-like illness (ILI) obtained Italian national system. also compared number positive swabs loads wastewater. Our investigated 189 samples. Results Cumulative ILI cases substantially overlapped load trends similar rise population. Therefore, confirmed co-circulation viruses during season 2022/2023, trend reported clinically cases. Conclusion does not replace traditional epidemiological methods, such as laboratory testing infected individuals. However, it be valuable complement obtaining additional information on preventing its spread.

Язык: Английский

Wastewater-Based Surveillance of Mpox (Monkeypox): An Early Surveillance Tool for Detecting Hotspots DOI Creative Commons
Md. Aminul Islam,

Rakesh Kumar,

Prabhakar Sharma

и другие.

Current Pollution Reports, Год журнала: 2024, Номер 10(2), С. 312 - 325

Опубликована: Май 21, 2024

Abstract Purpose of Review This study aims to review recent literature reporting wastewater-based surveillance (WBS) the monkeypox virus (MPXV) with a major focus on sample collection, processing, and public health safety issues. Recent Findings Various studies revealed presence MPXV genetic markers in sewage, wastewater treatment plants, drainage systems hospitals multiple countries. Summary Mpox (formally monkeypox) has been identified more than hundred countries, confirming at least 93,937 cases from 06 May 2022 03 February 2024. The MPXV, causative agent for mpox, is zoonotic having genome DNA. Major symptoms disease are rash, fever, headache, chills lymph pain. It about 10% case fatality rate, without any approved vaccine, but researchers investigating development therapeutic vaccines. DNA signature long reported urine, stool, saliva, semen, spit samples clinical patients, make feasible tracking wastewater. Furthermore, have environmental samples. As possible hosts (e.g., small mammals rodents), their detection might indicate circulation including non-human hosts. persistence infective particles ambient environment not fully investigated. Also, risks transmission through contaminated milieu unknown. WBS can be an effective tool identifying hotspots trends communities. Graphical

Язык: Английский

Процитировано

4

Acquired insights from the long-term surveillance of SARS-CoV-2 RNA for COVID-19 monitoring: The case of Monterrey Metropolitan Area (Mexico) DOI Creative Commons
Diego A. Padilla-Reyes, Mario Moisés Álvarez, Abrahan Mora

и другие.

Environmental Research, Год журнала: 2022, Номер 210, С. 112967 - 112967

Опубликована: Фев. 18, 2022

Wastewater-based epidemiology offers a time- and cost-effective way to monitor SARS-CoV-2 spread in communities therefore represents complement clinical testing. WBE applicability has been demonstrated number of cases over short-term periods as method for tracking the prevalence an early-warning tool predicting outbreaks population. This study reports viral loads from wastewater treatment plants (WWTPs) hospitals 6-month period (June December 2020). Results show that overall range load positive tested samples was between 1.2 × 10

Язык: Английский

Процитировано

15

Exploring the role of wastewater-based epidemiology in understanding tuberculosis burdens in Africa DOI Creative Commons
Hlengiwe N. Mtetwa, Isaac Dennis Amoah, Sheena Kumari

и другие.

Environmental Research, Год журнала: 2023, Номер 231, С. 115911 - 115911

Опубликована: Апрель 25, 2023

Tuberculosis (TB) remains a persistent challenge to public health and presents substantial menace, especially in developing nations of sub-Saharan Africa. It exerts considerable strain on healthcare systems these regions. Effective control requires reliable surveillance, which can be improved by incorporating environmental data alongside clinical data. Molecular advances have led the development alternative surveillance methods, such as wastewater-based epidemiology. This studyinvestigated presence, concentration, diversity Mycobacterium tuberculosis complex, cause TB, from six African countries: Ghana, Nigeria, Kenya, Uganda, Cameroon, South Samples were collected wastewater treatment plants. All samples found contain species that been linked TB both humans animals, including tuberculosis, bovis, africanum, caprae, at varying concentrations. The highest median concentration was reaching up 4.7 Log copies/ml for MTBC, 4.6 M. 3.4 africanum. presence africanum outside West Africa Africa, Uganda could indicate spread pathogen. study underscores usefulness epidemiology tracking shows even treated may pathogens, posing potential risks.

Язык: Английский

Процитировано

9

Wastewater-based epidemiology surveillance as an early warning system for SARS-CoV-2 in Indonesia DOI Creative Commons
Indah Kartika Murni, Vicka Oktaria, David McCarthy

и другие.

PLoS ONE, Год журнала: 2024, Номер 19(7), С. e0307364 - e0307364

Опубликована: Июль 18, 2024

Background Wastewater-based epidemiology (WBE) surveillance has been proposed as an early warning system (EWS) for community SARS-CoV-2 transmission. However, there is limited data from low-and middle-income countries (LMICs). This study aimed to assess the ability of WBE detect in formal and informal environments Indonesia using different methods sample collection, compare with patterns clinical cases COVID-19 within relevant communities, potential be used EWS outbreaks a community. Materials We conducted three districts Yogyakarta province, Indonesia, over eleven months (27 July 2021 7 January 2022 [Delta wave]; 18 3 June [Omicron wave]). Water samples grab, and/or passive sampling soil were collected either weekly or fortnightly. RNA was extracted membrane filters processed water directly soil. Reverse-transcription quantitative real-time polymerase chain reaction (RT-qPCR) performed N ORF1ab genes. Results A total 1,582 collected. Detection rates wastewater reflected incidence cases, 85% at peak 2% end Delta wave 94% 11% during Omicron wave. 2-week lag time observed between detection increasing corresponding Conclusion effective monitoring served system, predicting

Язык: Английский

Процитировано

3

Detection of influenza virus in urban wastewater during the season 2022/2023 in Sicily, Italy DOI Creative Commons
Carmelo Massimo Maida, Walter Mazzucco,

Walter Priano

и другие.

Frontiers in Public Health, Год журнала: 2024, Номер 12

Опубликована: Июль 23, 2024

Introduction Seasonal influenza generally represents an underestimated public health problem with significant socioeconomic implications. Monitoring and detecting epidemics are important tasks that require integrated strategies. Wastewater-based epidemiology (WBE) is emerging field uses wastewater data to monitor the spread of disease assess a community. It can represent integrative surveillance tool for better understanding prevention strategies in health. Methods We conducted study detected presence Influenza virus RNA using wastewater-based approach. Samples were collected from five treatment plants different municipalities, serving cumulative population 555,673 Sicilian inhabitants Italy. used RT-qPCR test compare combined weekly average A B viral samples incidence Influenza-like illness (ILI) obtained Italian national system. also compared number positive swabs loads wastewater. Our investigated 189 samples. Results Cumulative ILI cases substantially overlapped load trends similar rise population. Therefore, confirmed co-circulation viruses during season 2022/2023, trend reported clinically cases. Conclusion does not replace traditional epidemiological methods, such as laboratory testing infected individuals. However, it be valuable complement obtaining additional information on preventing its spread.

Язык: Английский

Процитировано

3