Environment International,
Год журнала:
2024,
Номер
184, С. 108478 - 108478
Опубликована: Фев. 1, 2024
Estuaries
serve
as
crucial
filters
for
land-based
pollutants
to
the
open
sea,
but
there
is
a
lack
of
information
on
migration
and
fate
organophosphate
flame
retardants
(OPFRs)
within
estuaries.
This
study
focused
Pearl
River
Estuary
(PRE)
by
examining
co-occurrence
OPFRs
their
metabolites
quantifying
transport
fluxes
using
mass
balance
model.
The
seawater
concentrations
exhibited
significant
seasonal
variations
(p
<
0.01),
while
sediment
reflected
long-term
distributional
equilibrium
in
PRE.
concentration
Σ
Environmental Science & Technology,
Год журнала:
2023,
Номер
57(18), С. 7109 - 7128
Опубликована: Апрель 20, 2023
Organophosphate
flame
retardants
(OPFRs)
are
found
in
various
environmental
matrixes
and
human
samples.
Exposure
to
OPFRs
during
gestation
may
interfere
with
pregnancy,
for
example,
inducing
maternal
oxidative
stress
hypertension
interfering
fetal
thyroid
hormone
secretion
neurodevelopment,
causing
metabolic
abnormalities.
However,
the
consequences
of
OPFR
exposure
on
pregnant
women,
impact
mother-to-child
transmission
OPFRs,
harmful
effects
pregnancy
outcomes
have
not
been
evaluated.
This
review
describes
women
worldwide,
based
metabolites
(mOPs)
urine
prenatal
breast
milk
postnatal
exposure.
Predictors
variability
mOPs
discussed.
Mother-to-child
pathways
scrutinized,
considering
levels
their
amniotic
fluid,
placenta,
deciduae,
chorionic
villi,
cord
blood.
The
results
showed
that
bis(1,3-dichloro-2-propyl)
phosphate
(BDCIPP)
diphenyl
(DPHP)
were
two
predominant
urine,
detection
frequencies
>90%.
estimated
daily
intake
(EDIM)
indicates
low
risk
when
infants
exposed
from
milk.
Furthermore,
higher
increase
adverse
influence
developmental
behavior
infants.
summarizes
knowledge
gaps
highlights
crucial
steps
assessing
health
risks
susceptible
populations,
such
as
fetuses.
Environmental Science & Technology,
Год журнала:
2023,
Номер
57(9), С. 3549 - 3561
Опубликована: Фев. 24, 2023
The
accumulation
and
trophodynamics
of
organophosphate
flame
retardants
(OPFRs)
their
metabolites
were
investigated
in
the
estuarine
food
web
Pearl
River,
China.
mean
∑OPFR
concentration
among
species
increased
following
order:
fish
[431
±
346
ng/g
lipid
weight
(lw)]
<
snail
(1310
621
lw)
shrimp
(1581
1134
crab
(1744
1397
lw).
di-alkyl
phosphates
(DAPs)
di-(n-butyl)
phosphate
(DNBP),
bis(2-butoxyethyl)
(BBOEP),
diphenyl
(DPHP)
most
abundant
metabolites,
with
concentrations
same
as
or
even
higher
than
corresponding
parent
compounds.
log
bioaccumulation
factors
for
OPFRs
lower
3.70,
significant
biomagnification
was
only
found
trisphenyl
[TPHP,
trophic
magnification
(TMFs)
>
1].
TMFs
OPFRs,
except
TPHP
tributyl
had
a
positive
correlation
lipophilicity
(log
KOW,
p
≤
0.05)
negative
biotransformation
rate
KM,
0.05).
TMF
1
observed
all
OPFR
based
on
bootstrap
regression
method.
"pseudo-biomagnification"
might
be
attributed
to
organisms
at
high
levels.
Environmental Science & Technology,
Год журнала:
2024,
Номер
58(14), С. 6402 - 6414
Опубликована: Март 28, 2024
Limited
knowledge
on
the
structure
of
emerging
organophosphorus
compounds
(OPCs)
hampers
our
comprehensive
understanding
their
environmental
occurrence
and
potential
risks.
Through
suspect
nontarget
screening,
combining
data-dependent
acquisition,
data-independent
parallel
reaction
monitoring
modes,
we
identified
60
OPCs
(17
traditional
43
compounds)
in
effluents
14
wastewater
treatment
plants
(WWTPs)
Beijing
Qinghai,
China.
These
comprise
26
organophosphate
triesters,
17
diesters,
6
organophosphonates,
7
organothiophosphate
esters,
4
other
OPCs.
Notably,
were
newly
WWTP
effluents,
16
discovered
matrices.
Specifically,
cyclic
phosphonate,
(5-ethyl-2-methyl-1,3,2-dioxaphosphorinan-5-yl)methyl
dimethyl
phosphonate
P-oxide
(PMMMPn),
consistently
appeared
all
with
semiquantitative
concentrations
ranging
from
44.4
to
282
ng/L.
Its
analogue,
di-PMMMPn,
presented
93%
samples.
Compositional
differences
between
two
cities
mainly
attributed
Hazard
ecological
risk
assessment
underscored
substantial
contribution
chlorinated
esters
overall
risks
effluents.
This
study
provides
most
OPC
profiles
date,
highlighting
need
for
further
research
occurrence,
fate,
risks,
particularly
Critical Reviews in Environmental Science and Technology,
Год журнала:
2024,
Номер
54(17), С. 1285 - 1305
Опубликована: Янв. 22, 2024
Lithium-ion
batteries
(LIBs)
industry
is
expanding
rapidly
in
the
context
of
addressing
challenge
climate
change
and
energy
crisis.
As
a
technology-intensive
product,
large
number
new
synthetic
chemicals
are
applied
LIBs
production.
Organic
fluorine
additives
added
multiple
components
LIBs,
many
these
novel
per-and
polyfluoroalkyl
substances
(with
fully
fluorinated
methyl
or
methylene
carbon
atom),
here,
this
work
we
referred
to
kind
compounds
as
LIB-PFAS.
LIB-PFAS
may
cause
high
exposure
personnel
contact
with
materials
during
production
disposal
processes,
thus
posing
potential
health
risks
occupational
workers.
The
general
population
can
be
exposed
when
they
released
into
surrounding
air,
soil,
water.
In
order
assess
associated
LIB-PFAS,
review
systematically
summarizes
chemical
structures,
analytical
methods,
possible
emission
routes
human
pathways,
their
bioaccumulation,
distribution,
elimination
behaviors
humans,
existing
toxicity
data
particular,
screening
identification
methods
for
57
discussed,
well
investigation
processes
manufacturing
LIB.
Although
available
scientific
still
limited,
provide
an
insightful
view
perspective
further
research
on
environmental
impacts
Environment International,
Год журнала:
2022,
Номер
163, С. 107209 - 107209
Опубликована: Март 28, 2022
Alkyl
organophosphate
flame
retardants
(OPFRs),
tri-n-butyl
phosphate
(TnBP)
and
tris(2-butoxyethyl)
(TBOEP),
are
ubiquitously
detected
in
indoor
outdoor
environments
their
inhalation
may
result
lung
damage.
This
study
examined
pulmonary
toxicity
after
exposure
to
TnBP
or
TBOEP
investigated
aggravation
of
inflammation
immunoreaction
by
an
ovalbumin
(OVA)-induced
mice
model.
Transcriptomics
were
used
further
reveal
the
underlying
mechanism.
Exposure
resulted
pathological
damage,
including
edema
thickened
alveolar
septum.
In
comparison
with
control,
enhanced
levels
superoxide
dismutase
(SOD)
(p
<
0.01
(High)
group
p
0.05
group),
glutathione
peroxidase
(GSH-px)
0.05),
malondialdehyde
(MDA)
0.01),
cytokines
under
a
dose-dependent
relationship
noted,
expression
Fkbp5/Nos3/MAPK/NF-кB
signaling
pathway
0.01)
was
upregulated
groups.
Moreover,
combined
OVA
exacerbated
allergic
inflammatory
response,
airway
hyperresponsiveness,
leukocytosis,
cellular
exudation
infiltration,
secretion
mediators,
higher
IgE
0.01).
results
demonstrated
that
PI3K/Akt/NF-кB
signal
involved
TnBP-aggravated
asthmatic
mice.
oxidative
damage
leukocyte-induced
injury.
can
facilitate
OVA-induced
asthma
through
response.
is
first
potential
mechanism
induced
OPFRs
in-vivo
