The Journal of School and University Medicine,
Год журнала:
2024,
Номер
11(02), С. 21 - 31
Опубликована: Янв. 1, 2024
Introduction:
Plastic
materials
represent
one
of
the
main
sources
waste,
affecting
environment
with
repercussions
on
human
body.
Until
recently,
this
topic
has
not
been
so
addressed,
possibly
because
many
incompletely
known
things,
but
also
large
industries
that
inevitably
use
plastic
and
want
to
promote
develop
their
businesses
maximum
potential.
The
following
material
presents
harmful
effects
components
can
have
health,
which
is
an
alarm
signal
for
public
health.
objective
study
highlight
Mps
Np
In
carrying
out
our
we
relied
qualitative
research,
while
relying
a
comprehensive
review
existing
literature
critical
comparative
analysis,
accessing
data
from
Science
Direct,
Google
Scholar,
journal
articles,
government
reports,
publications
international
environmental
organizations,
giving
priority
studies
published
in
recent
years.
Results:
affects
reproductive
system,
increase
risk
vascular
diseases,
last
least
these
particles
affect
skin,
changing
its
normal
functions.
impact
health
must
be
taken
into
account
tiny
all
factors:
water,
air,
soil,
biodiversity.
Keywords:
microplastic,
nano
plastic,
environment,
risk;
Environmental
enrichment
(EE)
is
commonly
included
as
an
important
component
of
animal
housing
to
promote
well
being
laboratory
animals;
however,
much
remains
be
learned
about
the
impact
chewable
forms
EE
on
experimental
outcomes
in
context
nutritional
and
microbiome-related
studies,
whether
differ
between
sexes.
In
present
study,
nylon
chew
bones
(gnaw
sticks,
GS)
were
evaluated
for
their
effects
fermentation
profiles,
microbial
community
structure,
cytokine
profiles
gastrointestinal
systemic
tissues
pair-housed
female
male
Sprague
Dawley
(SD)
rats.
Food
consumption
weight
gain
not
significantly
altered
by
access
GS.
Cecal
short-chain
fatty
acid
branched-chain
differed
sexes
rats
with
GS,
alpha
diversity
microbiome
decreased
females
provided
Sex-related
tissue
also
without
These
findings
indicate
that
including
GS
can
influence
microbiota
immune-related
parameters,
a
sex
dependent
manner.
This
shows
environmental
strategies
need
clearly
reported
publications
properly
evaluate
compare
results,
especially
respect
use
studies
examining
diet,
immune
parameters.
Environmental Research,
Год журнала:
2025,
Номер
273, С. 121254 - 121254
Опубликована: Фев. 28, 2025
The
adverse
effects
of
plastics
on
the
environment,
wildlife,
and
human
health
have
been
extensively
studied,
yet
their
production
remains
unavoidable
due
to
lack
viable
alternatives.
Environmental
fragmentation
larger
plastic
particles
generates
microplastics
(MPs,
0.1-5000
μm)
nanoplastics
(NPs,
1-100
nm),
which
can
enter
bloodstream
through
inhalation
or
ingestion.
This
review
examines
whether
MPs
NPs
influence
blood
pressure.
To
address
this
question,
relevant
studies
were
analyzed
based
predefined
criteria.
Due
anatomical
barriers
microcirculatory
dynamics,
only
small
are
expected
under
physiological
conditions,
although
pathological
states
may
alter
this.
In
vitro
research
indicates
that
negatively
affect
erythrocytes
endothelial
cells,
while
rodent
models
suggest
potential
cardiovascular
effects.
Plastic
fibers
detected
in
blood,
thrombi,
atherosclerotic
plaques,
various
tissues.
However,
validated
data
particle-related
pressure
changes
remain
lacking.
Despite
limitations
applicability
physiology,
preclinical
circulate
bloodstream,
interact
with
contribute
vascular
damage.
Mechanisms
such
as
injury,
platelet
activation,
inflammation,
MPs/NPs
accumulation
plaques
elevation
but
unlikely
be
exclusive
cause
hypertension.
Further
is
needed
clarify
role
regulation.
Standardized
detection
methods,
real-world
scenario-related
models,
targeted
essential
assessing
risks
associated
MP
NP
exposure.
Ecotoxicology and Environmental Safety,
Год журнала:
2024,
Номер
284, С. 116983 - 116983
Опубликована: Сен. 3, 2024
Microplastics
and
nanoplastics
(MNPs)
originating
from
plastic
pollution
pose
potential
threats
to
cardiovascular
health,
with
prior
studies
linking
MNPs
atherosclerosis.
Our
earlier
research
elucidated
how
enhance
macrophages'
phagocytic
activity,
leading
the
formation
of
foam
cells
an
elevated
risk
However,
specific
influence
on
smooth
muscle
(SMCs)
in
context
MNP-induced
atherosclerosis
remains
poorly
understood.
In
this
study,
ApoE
knockout
(ApoE
