Chronic sublethal exposure to chlorantraniliprole inhibits growth and development by disrupting the sugar and fatty acid metabolism in Spodoptera frugiperda

Pesticide Biochemistry and Physiology, Год журнала: 2025, Номер 208, С. 106302 - 106302

Опубликована: Янв. 13, 2025

Язык: Английский

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Current Insights into Sublethal Effects of Pesticides on Insects

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(11), С. 6007 - 6007

Опубликована: Май 30, 2024

The effect of pesticides on insects is often discussed in terms acute and chronic toxicity, but an important overlooked aspect the impact sublethal doses insect physiology behavior. Pesticides can influence various physiological parameters insects, including innate immune system, development, reproduction, through a combination direct effects specific exposed tissues modification behaviors that contribute to health reproductive success. Such include mobility, feeding, oviposition, navigation, ability detect pheromones. also have profound learning memory. precise depend many different factors, species, age, sex, caste, condition, as well type concentration active ingredients exposure route. More studies are needed assess (and combinations thereof) wider range species understand how decline. This review reflects our current knowledge about advancements development innovative methods them.

Язык: Английский

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New insights into chlorantraniliprole metabolic resistance mechanisms mediated by the striped rice borer cytochrome P450 monooxygenases: A case study of metabolic differences

The Science of The Total Environment, Год журнала: 2023, Номер 912, С. 169229 - 169229

Опубликована: Дек. 8, 2023

The anthranilic diamide insecticide chlorantraniliprole has been extensively applied to control Lepidoptera pests. However, its overuse leads the development of resistance and accumulation residue in environment. Four P450s (CYP6CV5, CYP9A68, CYP321F3, CYP324A12) were first found be constitutively overexpressed an SSB CAP-resistant strain. It is imperative further elucidate molecular mechanisms underlying P450s-mediated CAP for mitigating environmental contamination. Here, we heterologously expressed these four insect cells evaluated their abilities metabolize CAP. Western blotting reduced CO difference spectrum tests showed that P450 proteins had successfully Sf9 cells, which are indicative active functional enzymes. recombinant CYP6CV5, CYP324A12 exhibited a preference metabolizing fluorescent model probe substrates EC, BFC, EFC, EC with enzyme activities 0.54, 0.67, 0.57, 0.46 pmol/min/pmol P450, respectively. In vitro metabolism revealed distinct metabolic rates (0.97, 0.86, 0.75, 0.55 P450) efficiencies (0.45, 0.37, 0.30, 0.17) enzymes, thereby elucidating different protein catalytic activities. Furthermore, docking confirmed differences unveiled hydroxylation reaction generating N-demethylation methylphenyl during metabolism. Our findings not only provide new insights into at level but also demonstrate significant capacities multiple degradation facilitate evaluation mitigation toxic risks associated application

Язык: Английский

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Thiamethoxam-Induced Intergenerational Sublethal Effects on the Life History and Feeding Behavior of Rhopalosiphum padi

Plants, Год журнала: 2024, Номер 13(6), С. 865 - 865

Опубликована: Март 17, 2024

Thiamethoxam, a second-generation neonicotinoid insecticide is widely used for controlling sap-sucking insect pests including Rhopalosiphum padi. The current study aimed to investigate the life-history parameters and feeding behavior of R. padi following treatments with sublethal concentrations thiamethoxam. lethal concentration 50 (LC50) value thiamethoxam against adult was 11.458 mg L−1 after 48 h exposure. (LC5 LC10) significantly decreased longevity, fecundity, reproductive days in directly exposed aphids (F0 generation). In progeny (F1), developmental durations total prereproductive period (TPRP) were while (RPd) increased at both concentrations. demographic net rate (R0), intrinsic increase (r), finite (λ) prolonged only LC5 EPG results indicated that increases duration non-probing (Np) reducing E2 (F0). Interestingly, generation (F1) descending from previously parental Overall, this showed exhibited high toxicity individuals (F0), inducing intergenerational hormetic effects on These findings provided crucial details about thiamethoxam-induced might be useful managing resurgences key pest.

Язык: Английский

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Larvicidal activity against Phenolia (Lasiodites) picta (Coleoptera: Nitidulidae) on jujube (Zizyphus jujuba Miller var. Inermis Rehder) and the improvement of high-quality fruit production using Bacillus licheniformis PR2

Biological Control, Год журнала: 2025, Номер unknown, С. 105739 - 105739

Опубликована: Март 1, 2025

Язык: Английский

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Heat‐stress memory enhances the acclimation of a migratory insect pest to global warming

Molecular Ecology, Год журнала: 2024, Номер 33(17)

Опубликована: Авг. 12, 2024

In the face of rising global temperatures, mechanisms behind an organism's ability to acclimate heat stress remain enigmatic. The rice leaf folder, Cnaphalocrocis medinalis, traditionally viewed as temperature-sensitive, paradoxically exhibits robust larval acclimation stress. This study used heat-acclimated strain HA39, developed through multigenerational exposure 39°C during stage, and unacclimated HA27 reared at 27°C unravel transgenerational effects its regulatory mechanisms. Heat for larvae incurred a fitness cost in pupae when exposed high temperature, yet significant effect surfaced, revealing heightened benefit from even without additional recovery 27°C. exhibited short-term memory, diminishing after two generations. Moreover, correlated with increased superoxide dismutase (SOD) enzyme activity expression levels oxidoreductase genes, representing physiological molecular foundations acclimation. Heat-acclimated displayed elevated DNA methylation levels, while generations, decreased indicated by upregulation demethylase gene downregulation methyltransferase genes temperatures. summary, induces methylation, orchestrating heat-stress memory influencing SOD activity. Heat-stress enhances migratory insect pest warming.

Язык: Английский

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Transgenerational effect of a tea saponin–matrine mixture promotes fecundity and alters associated bacteria in the fall armyworm Spodoptera frugiperda

Industrial Crops and Products, Год журнала: 2024, Номер 213, С. 118472 - 118472

Опубликована: Март 29, 2024

Язык: Английский

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Toxicity and residual activity of insecticides to Grapholita molesta (Lepidoptera: Tortricidae) in apple orchards: implications for insecticide resistance management

Journal of Economic Entomology, Год журнала: 2024, Номер unknown

Опубликована: Окт. 21, 2024

Organophosphate (OP) insecticides have been used to control Grapholita molesta (Busck, 1916) in Brazil since 1990. However, the evolution of pest insecticide resistance and toxicological reassessments has led replacement OPs with other chemical groups. This study evaluated toxicity abamectin + cyantraniliprole (1.1 3.7 g a.i./100 L-1), acetamiprid etofenproxi (9.1 16.5 emamectin benzoate (0.5 Sophora flavescens (Fabales: Fabaceae) (22.8 phosmet (87.5 indoxacarb (11.2 L-1) eggs, larvae, adults G. molesta. Additionally, residual activity these apple orchards was assessed, diagnostic concentration for monitoring estimated using LC99 values (Lethal Concentration that causes 99% mortality a susceptible population). In larval studies, all resulted rates more than 90%. The reduced hatching by 99%. caused over 80% adult had 14-day orchards. (μg.ml-1) were 1.75 (indoxacarb), 6.45 (metaflumizone), 9.10 (acetamiprid etofenproxi), 9.67 (Sophora flavescens), 36.13 (phosmet), 45.61 (abamectin cyantraniliprole). high molesta, being new tools integrated management

Язык: Английский

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Multigenerational Hormetic Effects of different Insecticides on Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae)

Crop Protection, Год журнала: 2024, Номер 187, С. 106962 - 106962

Опубликована: Сен. 24, 2024

Язык: Английский

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