Effect of Fluoride on Gut Microbiota: A Systematic Review DOI Creative Commons
Momina Yasin, Fatemeh Vida Zohoori, Elizabeth Adjoa Kumah

и другие.

Nutrition Reviews, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 21, 2024

Fluoride can prevent dental caries by inhibiting demineralization and promoting remineralization of teeth while affecting the physiology oral microbiota, thus cellular enzymes. However, effect systemic fluoride on gut microbiota is unknown. To explore impacts composition abundance associated functions such as gene metabolic regulation. A systematic database search was conducted MEDLINE, Web Science, Scopus, PubMed, CINAHL, Embase to find articles studies reporting effects microbiota. Forty-nine were included (n = 42 in animals, 4 humans, 3 vitro studies) after screening for title, abstract, full text using Covidence check against eligibility criteria. Data extracted study quality assessed Mixed Method Appraisal Tool 2 reviewers independently. Two human fluorosis 1 patients with breast cancer (intestinal fluorine-18 fluorodeoxyglucose uptake) showed significant differences microbial composition, increased relative Acidobacteria Proteobacteria, decreased Firmicutes Bacteroidetes. An ex vivo feces indicated that ≤ mg L-1 NaF might boost "health-associated" taxa, but concentrations (≥ 10 NaF) could increase ratio some unhealthy microbes 24 hours. The animal examined high doses water diet (50-1200 long-term (1-6 months) short-term (6 hours 7 days) exposure, all showing a disturbance Bacteroidota ratio. In potentially may be detrimental microbiome, whereas had positive effects. Similarly, ≥ 50 unsafe, 25 harmless PROSPERO registration No. CRD42022347357.

Язык: Английский

F-53B disrupts energy metabolism by inhibiting the V-ATPase-AMPK axis in neuronal cells DOI
Yue Zhang, Tingting Li,

Xueman Ding

и другие.

Journal of Hazardous Materials, Год журнала: 2025, Номер 487, С. 137111 - 137111

Опубликована: Янв. 5, 2025

Язык: Английский

Процитировано

2
F-53B mediated ROS affects uterine development in rats during puberty by inducing apoptosis DOI Creative Commons
Penghui Nie,

Yuzhi Lan,

Tao You

и другие.

Ecotoxicology and Environmental Safety, Год журнала: 2024, Номер 277, С. 116399 - 116399

Опубликована: Апрель 26, 2024

Perfluoroalkyl and polyfluoroalkyl substances (PFASs), as pollutants, can cause palpable environmental health impacts around the world, endocrine disruptors, disrupt homeostasis increase risk of diseases. Chlorinated ether sulfonate (F-53B), a substitute for PFAS, was determined to have potential toxicity. Puberty is stage when sexual organs develop hormones change dramatically, abnormal uterine development lesions lead infertility. This study designed explore impact F-53B on during puberty. Four-week-old female SD rats were exposed 0.125 6.25 mg/L The results showed that interfered with growth sex hormone levels bound oestrogen-related receptors, which affected their function, contributed accumulation reactive oxygen species, promoted cell apoptosis inhibited proliferation, ultimately causing dysplasia.

Язык: Английский

Процитировано

6
Contribution of gut microbiota to hepatic steatosis following F-53B exposure from the perspective of glucose and fatty acid metabolism DOI
Xueyan Gu,

Huihui Yang,

Wu Liu

и другие.

Journal of Hazardous Materials, Год журнала: 2024, Номер 480, С. 136104 - 136104

Опубликована: Окт. 9, 2024

Язык: Английский

Процитировано

3
Adolescent F-53B exposure induces ovarian toxicity in rats: Autophagy-apoptosis interplay DOI

Yuzhi Lan,

Penghui Nie, Qiang Yu

и другие.

The Science of The Total Environment, Год журнала: 2024, Номер 951, С. 175609 - 175609

Опубликована: Авг. 18, 2024

Язык: Английский

Процитировано

1
Lactiplantibacillus plantarum P101-fermented Luffa cylindrica Juice Alleviate F-53B-Induced Liver Steatosis in Mice via the Gut-liver axis DOI
X. R. Wang,

Tiancheng Zhao,

Jinfeng Zhang

и другие.

Food Bioscience, Год журнала: 2024, Номер 62, С. 105442 - 105442

Опубликована: Ноя. 8, 2024

Язык: Английский

Процитировано

0
Effect of Fluoride on Gut Microbiota: A Systematic Review DOI Creative Commons
Momina Yasin, Fatemeh Vida Zohoori, Elizabeth Adjoa Kumah

и другие.

Nutrition Reviews, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 21, 2024

Fluoride can prevent dental caries by inhibiting demineralization and promoting remineralization of teeth while affecting the physiology oral microbiota, thus cellular enzymes. However, effect systemic fluoride on gut microbiota is unknown. To explore impacts composition abundance associated functions such as gene metabolic regulation. A systematic database search was conducted MEDLINE, Web Science, Scopus, PubMed, CINAHL, Embase to find articles studies reporting effects microbiota. Forty-nine were included (n = 42 in animals, 4 humans, 3 vitro studies) after screening for title, abstract, full text using Covidence check against eligibility criteria. Data extracted study quality assessed Mixed Method Appraisal Tool 2 reviewers independently. Two human fluorosis 1 patients with breast cancer (intestinal fluorine-18 fluorodeoxyglucose uptake) showed significant differences microbial composition, increased relative Acidobacteria Proteobacteria, decreased Firmicutes Bacteroidetes. An ex vivo feces indicated that ≤ mg L-1 NaF might boost "health-associated" taxa, but concentrations (≥ 10 NaF) could increase ratio some unhealthy microbes 24 hours. The animal examined high doses water diet (50-1200 long-term (1-6 months) short-term (6 hours 7 days) exposure, all showing a disturbance Bacteroidota ratio. In potentially may be detrimental microbiome, whereas had positive effects. Similarly, ≥ 50 unsafe, 25 harmless PROSPERO registration No. CRD42022347357.

Язык: Английский

Процитировано

0