F-53B disrupts energy metabolism by inhibiting the V-ATPase-AMPK axis in neuronal cells
Journal of Hazardous Materials,
Год журнала:
2025,
Номер
487, С. 137111 - 137111
Опубликована: Янв. 5, 2025
Язык: Английский
F-53B mediated ROS affects uterine development in rats during puberty by inducing apoptosis
Ecotoxicology and Environmental Safety,
Год журнала:
2024,
Номер
277, С. 116399 - 116399
Опубликована: Апрель 26, 2024
Perfluoroalkyl
and
polyfluoroalkyl
substances
(PFASs),
as
pollutants,
can
cause
palpable
environmental
health
impacts
around
the
world,
endocrine
disruptors,
disrupt
homeostasis
increase
risk
of
diseases.
Chlorinated
ether
sulfonate
(F-53B),
a
substitute
for
PFAS,
was
determined
to
have
potential
toxicity.
Puberty
is
stage
when
sexual
organs
develop
hormones
change
dramatically,
abnormal
uterine
development
lesions
lead
infertility.
This
study
designed
explore
impact
F-53B
on
during
puberty.
Four-week-old
female
SD
rats
were
exposed
0.125
6.25
mg/L
The
results
showed
that
interfered
with
growth
sex
hormone
levels
bound
oestrogen-related
receptors,
which
affected
their
function,
contributed
accumulation
reactive
oxygen
species,
promoted
cell
apoptosis
inhibited
proliferation,
ultimately
causing
dysplasia.
Язык: Английский
Contribution of gut microbiota to hepatic steatosis following F-53B exposure from the perspective of glucose and fatty acid metabolism
Journal of Hazardous Materials,
Год журнала:
2024,
Номер
480, С. 136104 - 136104
Опубликована: Окт. 9, 2024
Язык: Английский
Adolescent F-53B exposure induces ovarian toxicity in rats: Autophagy-apoptosis interplay
The Science of The Total Environment,
Год журнала:
2024,
Номер
951, С. 175609 - 175609
Опубликована: Авг. 18, 2024
Язык: Английский
Lactiplantibacillus plantarum P101-fermented Luffa cylindrica Juice Alleviate F-53B-Induced Liver Steatosis in Mice via the Gut-liver axis
Food Bioscience,
Год журнала:
2024,
Номер
62, С. 105442 - 105442
Опубликована: Ноя. 8, 2024
Язык: Английский
Effect of Fluoride on Gut Microbiota: A Systematic Review
Nutrition Reviews,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 21, 2024
Fluoride
can
prevent
dental
caries
by
inhibiting
demineralization
and
promoting
remineralization
of
teeth
while
affecting
the
physiology
oral
microbiota,
thus
cellular
enzymes.
However,
effect
systemic
fluoride
on
gut
microbiota
is
unknown.
To
explore
impacts
composition
abundance
associated
functions
such
as
gene
metabolic
regulation.
A
systematic
database
search
was
conducted
MEDLINE,
Web
Science,
Scopus,
PubMed,
CINAHL,
Embase
to
find
articles
studies
reporting
effects
microbiota.
Forty-nine
were
included
(n
=
42
in
animals,
4
humans,
3
vitro
studies)
after
screening
for
title,
abstract,
full
text
using
Covidence
check
against
eligibility
criteria.
Data
extracted
study
quality
assessed
Mixed
Method
Appraisal
Tool
2
reviewers
independently.
Two
human
fluorosis
1
patients
with
breast
cancer
(intestinal
fluorine-18
fluorodeoxyglucose
uptake)
showed
significant
differences
microbial
composition,
increased
relative
Acidobacteria
Proteobacteria,
decreased
Firmicutes
Bacteroidetes.
An
ex
vivo
feces
indicated
that
≤
mg
L-1
NaF
might
boost
"health-associated"
taxa,
but
concentrations
(≥
10
NaF)
could
increase
ratio
some
unhealthy
microbes
24
hours.
The
animal
examined
high
doses
water
diet
(50-1200
long-term
(1-6
months)
short-term
(6
hours
7
days)
exposure,
all
showing
a
disturbance
Bacteroidota
ratio.
In
potentially
may
be
detrimental
microbiome,
whereas
had
positive
effects.
Similarly,
≥
50
unsafe,
25
harmless
PROSPERO
registration
No.
CRD42022347357.
Язык: Английский