Effects of Biochar on Tire Wear Particle-Derived 6PPD, 6PPD-Q, and Antimony Levels and Microbial Community in Soil

Journal of Hazardous Materials, Год журнала: 2025, Номер unknown, С. 137951 - 137951

Опубликована: Март 1, 2025

Язык: Английский

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Environmental Concentrations of 6PPD and 6PPD-Quinone Induce Hepatic Lipid Metabolism Disorders in Male Black-Spotted Frogs

Journal of Hazardous Materials, Год журнала: 2024, Номер 480, С. 136400 - 136400

Опубликована: Ноя. 4, 2024

Язык: Английский

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Multigenerational toxic effects in Daphnia pulex are induced by environmental concentrations of tire wear particle leachate

Journal of Hazardous Materials, Год журнала: 2024, Номер 486, С. 136977 - 136977

Опубликована: Дек. 24, 2024

Язык: Английский

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Tire rubber-derived contaminants 6PPD and 6PPD-quinone reduce attachment and outgrowth of trophoblast spheroids onto endometrial epithelial cells

Ecotoxicology and Environmental Safety, Год журнала: 2025, Номер 290, С. 117744 - 117744

Опубликована: Янв. 1, 2025

N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD), a synthetic additive widely used in the rubber industry, and its oxidized product 6PPD-quinone (6PPDQ), have garnered widespread attention as an emerging hazardous chemicals owing to their potential detrimental effects on aquatic ecosystem human health. The of 6PPD 6PPDq female reproductive tract, especially embryo implantation, remain unknown were investigated this study. We spheroid attachment outgrowth models BeWo trophoblastic spheroids Ishikawa cells surrogates for blastocyst endometrial epithelium, respectively. Treatment with up 48 h decreased viability dose- cell line-dependent manner (20-100 μM 10-100 6PPDQ both lines). At noncytotoxic concentration, exposure 1 10 reduced further inhibited invasion epithelial monolayer. A similar result was observed 6PPDQ-exposed groups. Gene expression profiling 6PPD- revealed that differentially regulated panel transcript markers toward overall downregulation receptivity invasion. study provides first proof adverse trophoblast during window warranting need vivo clinical studies.

Язык: Английский

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Molecular insight on conformational alterations and functional changes of acetylcholinesterase induced by an emerging environmental pollutant 6PPD-quinone

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 305, С. 141205 - 141205

Опубликована: Фев. 17, 2025

Язык: Английский

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Residues of 6PPD-Q in the Aquatic Environment and Toxicity to Aquatic Organisms: A Review

Fishes, Год журнала: 2025, Номер 10(4), С. 146 - 146

Опубликована: Март 25, 2025

N-(1,3-dimethylbutyl)-N’-phenyl-p-benzoquinone (6PPD-Q) is an emerging environmental contaminant that widely distributed in aquatic environments and presents significant toxicological risks to organisms. As 6PPD-Q primarily derived from oxidative transformation of the tire antioxidant N-(1,3-dimethylbutyl)-N’-phenyl-p-phenylenediamine (6PPD), its persistence potential for bioaccumulation organisms have raised widespread concerns. This study reviews sources, spatial distribution, migration, behaviors 6PPD-Q, as well degradation mechanisms different media. Additionally, this review systematically explores effects on organisms, including physiological, biochemical, molecular impacts fish, crustaceans, mollusks, algae, with a focus mechanisms. Finally, we discuss limitations current research propose key directions future studies, long-term ecological risk assessments, bioaccumulation, metabolic pathway analysis, optimization pollution control strategies, aiming provide scientific basis assessment management 6PPD-Q.

Язык: Английский

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A bibliometric analysis of global research hotspots and progress on emerging environmental pollutants 6PPD and 6PPD-quinone from 2004 to 2024

Environmental Pollution, Год журнала: 2024, Номер unknown, С. 124969 - 124969

Опубликована: Сен. 1, 2024

Язык: Английский

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Phytotoxicity of 6PPD and its uptake by Myriophyllum verticillatum: Oxidative stress and metabolic processes

The Science of The Total Environment, Год журнала: 2024, Номер 955, С. 177248 - 177248

Опубликована: Ноя. 1, 2024

Язык: Английский

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Response of Ceratophyllum demersum L. and its epiphytic biofilms to 6PPD and 6PPD-Q exposure: Based on metabolomics and microbial community analysis

Journal of Hazardous Materials, Год журнала: 2024, Номер 480, С. 136420 - 136420

Опубликована: Ноя. 5, 2024

Язык: Английский

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Chronic toxicity and intergenerational effects of N-(1,3-dimethylbutyl)-N’-phenyl-p-phenylenediamine (6PPD) exposure alone and in combination with Zn2+ on Daphnia magna (Cladocera)

Ecotoxicology, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 29, 2024

Язык: Английский

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