Do all fungi have ancestors with endophytic lifestyles?

Fungal Diversity, Год журнала: 2023, Номер 125(1), С. 73 - 98

Опубликована: Март 16, 2023

Язык: Английский

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Current trends, limitations and future research in the fungi?

Fungal Diversity, Год журнала: 2024, Номер 125(1), С. 1 - 71

Опубликована: Март 20, 2024

Abstract The field of mycology has grown from an underappreciated subset botany, to a valuable, modern scientific discipline. As this study grown, there have been significant contributions science, technology, and industry, highlighting the value fungi in era. This paper looks at current research, along with existing limitations, suggests future areas where scientists can focus their efforts, mycology. We show how become important emerging diseases medical discuss trends potential drug novel compound discovery. explore phylogenomics, its potential, outcomes address question phylogenomics be applied fungal ecology. In addition, functional genomics studies are discussed importance unravelling intricate mechanisms underlying behaviour, interactions, adaptations, paving way for comprehensive understanding biology. look research building materials, they used as carbon sinks, biocircular economies. numbers always great interest often written about estimates varied greatly. Thus, we needs order obtain more reliable estimates. aspects machine learning (AI) it mycological research. Plant pathogens affecting food production systems on global scale, such, needed area, particularly disease detection. latest data High Throughput Sequencing if still gaining new knowledge same rate before. A review nanotechnology is provided addressed. Arbuscular Mycorrhizal Fungi addressed acknowledged. Fungal databases becoming important, therefore provide major databases. Edible medicinal huge medicines, especially Asia prospects discussed. Lifestyle changes (e.g., endophytes, pathogens, and/or saprobes) also extremely trend special issue Diversity.

Язык: Английский

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Ten decadal advances in fungal biology leading towards human well-being

Fungal Diversity, Год журнала: 2022, Номер 116(1), С. 547 - 614

Опубликована: Сен. 1, 2022

Fungi are an understudied resource possessing huge potential for developing products that can greatly improve human well-being. In the current paper, we highlight some important discoveries and developments in applied mycology interdisciplinary Life Science research. These examples concern recently introduced drugs treatment of infections neurological diseases; application -OMICS techniques genetic tools medical regulation mycotoxin production; as well highlights mushroom cultivaton Asia. Examples new diagnostic exploitation candidates therapeutic drugs, also given. addition, two entries illustrating latest use fungi biodegradation fungal biomaterial production provided. Some other areas where there have been and/or will be significant included. It is our hope this paper help realise importance a industrial see next decades bring forward many fungus-derived products.

Язык: Английский

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Curiouser and curiouser: progress in understanding the programming of iterative highly-reducing polyketide synthases

Natural Product Reports, Год журнала: 2022, Номер 40(1), С. 9 - 27

Опубликована: Май 11, 2022

Current understanding of iterative highly programmed Type 1 PKS that control starter unit selection, chain length, methylation pattern, and stereochemistry.

Язык: Английский

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Fungal perylenequinones

Mycological Progress, Год журнала: 2022, Номер 21(3)

Опубликована: Март 1, 2022

Язык: Английский

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Segregation of the genus Parahypoxylon (Hypoxylaceae, Xylariales) from Hypoxylon by a polyphasic taxonomic approach

MycoKeys, Год журнала: 2023, Номер 95, С. 131 - 162

Опубликована: Фев. 20, 2023

During a mycological survey of the Democratic Republic Congo, fungal specimen that morphologically resembled American species Hypoxylonpapillatum was encountered. A polyphasic approach including morphological and chemotaxonomic together with multigene phylogenetic study (ITS, LSU, tub2, rpb2) Hypoxylon spp. representatives related genera revealed this strain represents new Hypoxylaceae. However, multi-locus inference indicated fungus clustered H.papillatum in separate clade from other Hypoxylon. Studies by ultrahigh performance liquid chromatography coupled to diode array detection ion mobility tandem mass spectrometry (UHPLC-DAD-IM-MS/MS) were carried out on stromatal extracts. In particular, MS/MS spectra major metabolites these production hitherto unreported azaphilone pigments similar core scaffold cohaerin-type metabolites, which are exclusively found Based results, genus Parahypoxylon is introduced herein. Aside P.papillatum, also includes P.ruwenzoriensesp. nov., type within basal Hypoxylaceae its sister Durotheca.

Язык: Английский

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Isolation and Identification of Pigment-Producing Endophytic Fungi from the Amazonian Species Fridericia chica

Journal of Fungi, Год журнала: 2024, Номер 10(1), С. 77 - 77

Опубликована: Янв. 19, 2024

Pigments of fungal origin have aroused increasing interest in the food dye and cosmetic industries since global demand for natural dyes has grown. Endophytic microorganisms are a source bioactive compounds, Amazonian plant species can harbor fungi with wide range biotechnological applications. Popularly known Brazil as crajiru, Fridericia chica is medicinal that produces red pigment. In this study, total 121 were isolated potato dextrose agar from three plants. We identified nine pigment-producing endophytic branches leaves F. chica. The isolates showed pigment production solid media molecularly via multilocus analysis Aspergillus welwitschiae, A. sydowii, Curvularia sp., Diaporthe cerradensis (two strains), Hypoxylon investiens, Neoscytalidium sp. strains) Penicillium rubens. These subjected to submerged fermentation two culture obtain metabolic extracts. extracts obtained analyzed terms their absorbance between 400 700 nm. pigmented extract produced by H. investiens medium containing yeast maximum absorption (UA700 = 0.550) significant antioxidant antimicrobial activity. This isolate thus be considered new extracellular

Язык: Английский

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A Comprehensive Review of the Diversity of Fungal Secondary Metabolites and Their Emerging Applications in Healthcare and Environment

Mycobiology, Год журнала: 2024, Номер 52(6), С. 335 - 387

Опубликована: Ноя. 1, 2024

Fungi and their natural products, like secondary metabolites, have gained a huge demand in the last decade due to increasing applications healthcare, environmental cleanup, biotechnology-based industries. The fungi produce these metabolites (SMs) during different phases of growth, which are categorized into terpenoids, alkaloids, polyketides, non-ribosomal peptides. These SMs exhibit significant biological activity, contributes formulation novel pharmaceuticals, biopesticides, bioremediation agents. Nowadays, fungal-derived widely used food beverages, for fermentation, preservatives, protein sources, dairy In it is being as an antimicrobial, anticancer, anti-inflammatory, immunosuppressive drug. usage modern tools biotechnology can achieve increase large-scale production. present review comprehensively analyses diversity fungal along with emerging agriculture, sustainability, nutraceuticals. Here, authors reviewed recent advancements genetic engineering, metabolic pathway manipulation, synthetic biology improve production yield SMs. Advancement fermentation techniques, bioprocessing, co-cultivation approaches Investigators further highlighted importance omics technologies understanding regulation biosynthesis SMs, offers drug discovery sustainable agriculture. Finally, addressed potential manipulation biotechnological innovations exploitation commercial benefits.

Язык: Английский

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Diversity of biologically active secondary metabolites in the ascomycete order Sordariales

Mycological Progress, Год журнала: 2022, Номер 21(4)

Опубликована: Апрель 1, 2022

Abstract Ascomycetes belonging to the order Sordariales are a well-known reservoir of secondary metabolites with potential beneficial applications. Species ubiquitous, and they commonly found in soils lignicolous, herbicolous, coprophilous habitats. Some their species have been used as model organisms modern fungal biology or were be prolific producers potentially useful metabolites. However, majority sordarialean poorly studied. Traditionally, classification has mainly based on morphology ascomata, ascospores, asexual states, characters that demonstrated homoplastic by taxonomic studies multi-locus phylogeny. Herein, we summarize for first time relevant information about available knowledge biological activities exerted representatives this order, well current outlook opportunities recent advances omic tools could bring discovery order.

Язык: Английский

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Rapid discovery of terpene tailoring enzymes for total biosynthesis

Chemical Science, Год журнала: 2023, Номер 14(46), С. 13463 - 13467

Опубликована: Янв. 1, 2023

Twenty oxygenated aristolochene congeners were rapidly synthesised by combining genes from four different fungal pathways in the host organism Aspergillus oryzae .

Язык: Английский

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