Ultra-high sensitivity electrochemical aptamer biosensor based on a carbon nano-confined interface for the detection of aflatoxin B1 in traditional chinese materia medica decoction pieces
Carbon letters,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 10, 2025
Язык: Английский
Fluorescent nanosensors for detection of microbial toxins in food matrices: a review
Harpreet Singh,
Dinesh Kumar,
Akash Deep
и другие.
Journal of Food Measurement & Characterization,
Год журнала:
2024,
Номер
18(9), С. 7669 - 7699
Опубликована: Июль 27, 2024
Язык: Английский
Leveraging Concentration Imbalance-Driven DNA Circuit as an Operational Amplifier to Enhance the Sensitivity of Hepatitis B Virus DNA Detection with Hybridization-Responsive DNA-Templated Silver Nanoclusters
JACS Au,
Год журнала:
2024,
Номер
4(6), С. 2323 - 2334
Опубликована: Май 31, 2024
Hepatitis
B
virus
(HBV)
infection
remains
a
major
global
health
concern,
necessitating
the
development
of
sensitive
and
reliable
diagnostic
methods.
In
this
study,
we
propose
novel
approach
to
enhance
sensitivity
HBV
DNA
detection
by
leveraging
concentration
imbalance-driven
circuit
(CIDDC)
as
an
operational
amplifier,
coupled
with
hybridization-responsive
DNA-templated
silver
nanocluster
(DNA-AgNCs)
nanoprobe
named
Q·C6-AgNCs.
The
CIDDC
system
effectively
converts
amplifies
input
into
enriched
generic
single-stranded
output,
which
subsequently
triggers
fluorescence
DNA-AgNCs
reporter
upon
hybridization,
generating
measurable
signal
for
detection.
By
incorporating
circuit,
not
only
achieved
enhanced
lower
limit
0.11
nM
but
also
demonstrated
high
specificity
single-base
mismatch
discriminability
Additionally,
mix-and-detect
assay
format
is
simple,
user-friendly,
isothermal.
This
innovative
strategy
holds
promise
advancing
molecular
diagnostics
facilitating
effective
management
HBV-related
diseases.
Язык: Английский
A fluorescent aptasensor for kanamycin detection in milk, seafood and water samples using DNA-AgNCs and exonuclease I-assisted recycling amplification strategy
Food Chemistry,
Год журнала:
2025,
Номер
unknown, С. 143291 - 143291
Опубликована: Фев. 1, 2025
Язык: Английский
Emerging applications of biorecognition elements-based optical biosensors for food safety monitoring
Опубликована: Фев. 14, 2025
Язык: Английский
A Ratiometric Fluorescence Detection Method for Berberine Using Triplex-Containing DNA-Templated Silver Nanoclusters
Опубликована: Июнь 17, 2024
Berberine
(BBR),
as
a
natural
isoquinoline
alkaloid,
has
been
demonstrated
various
pharmacological
activities,
and
widely
applied
in
the
treatment
of
diseases.
The
quantitative
analysis
BBR
is
important
for
its
researches
clinical
applications.
In
work,
utilizing
specific
interaction
between
triplex
DNA,
sensitive
selective
fluorescent
detecting
method
was
established
with
DNA-templated
silver
nanoclusters
(DNA-AgNCs).
After
binding
structure
template
DNA-AgNCs,
quenched
fluorescence
DNA-AgNCs
formed
BBR-triplex
complex
yellow-green
fluorescence.
ratiometric
signal
showed
linear
relationship
concentration
range
10
nM
to
1000
nM,
detect
limit
nM.
Our
exhibited
excellent
sensitivity
selectivity,
it
further
detection
real
samples.
Язык: Английский
DNA-Templated Fluorescent Metal Nanoclusters and Their Illuminating Applications
Nanoscale,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
After
the
discovery
of
DNA
during
mid-20
th
century,
a
multitude
novel
methodologies
have
surfaced
which
exploit
for
its
various
properties.
Язык: Английский
A Ratiometric Fluorescence Detection Method for Berberine Using Triplex-Containing DNA-Templated Silver Nanoclusters
Molecules,
Год журнала:
2024,
Номер
29(15), С. 3459 - 3459
Опубликована: Июль 24, 2024
Berberine
(BBR),
as
a
natural
isoquinoline
alkaloid,
has
demonstrated
various
pharmacological
activities,
and
is
widely
applied
in
the
treatment
of
diseases.
The
quantitative
analysis
BBR
important
for
studies
clinical
applications.
In
this
work,
utilizing
specific
interaction
between
triplex
DNA,
sensitive
selective
fluorescent
detecting
method
was
established
with
DNA-templated
silver
nanoclusters
(DNA-AgNCs).
After
binding
structure
template
DNA-AgNCs,
quenched
fluorescence
DNA-AgNCs
formed
BBR-triplex
complex
yellow-green
fluorescence.
ratiometric
signal
showed
linear
relationship
concentration
range
from
10
nM
to
1000
nM,
detection
limit
nM.
Our
exhibited
excellent
sensitivity
selectivity,
further
real
samples.
Язык: Английский
Recent Advances of Strategies and Applications in Aptamer-Combined Metal Nanocluster Biosensing Systems
Biosensors,
Год журнала:
2024,
Номер
14(12), С. 625 - 625
Опубликована: Дек. 18, 2024
Metal
nanoclusters
(NCs)
are
promising
alternatives
to
organic
dyes
and
quantum
dots.
These
NCs
exhibit
unique
physical
chemical
properties,
such
as
fluorescence,
chirality,
magnetism
catalysis,
which
contribute
significant
advancements
in
biosensing,
biomedical
diagnostics
therapy.
Through
adjustments
composition,
size,
environments
surface
ligands,
it
is
possible
create
with
tunable
optoelectronic
catalytic
activity.
This
review
focuses
on
the
integration
of
aptamers
metal
NCs,
detailing
molecular
detection
strategies
that
utilise
effect
optical
signal
emission
NC-based
biosensing
systems.
also
highlights
recent
applications,
well
illustrative
case
studies.
To
conclude,
strengths,
limitations,
current
challenges
prospects
for
systems
were
examined.
Язык: Английский