Recent Advances of Strategies and Applications in Aptamer-Combined Metal Nanocluster Biosensing Systems DOI Creative Commons

K. H. Kim,

Sang-Ho Kim,

Seung Min Yoo

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(12), P. 625 - 625

Published: Dec. 18, 2024

Metal nanoclusters (NCs) are promising alternatives to organic dyes and quantum dots. These NCs exhibit unique physical chemical properties, such as fluorescence, chirality, magnetism catalysis, which contribute significant advancements in biosensing, biomedical diagnostics therapy. Through adjustments composition, size, environments surface ligands, it is possible create with tunable optoelectronic catalytic activity. This review focuses on the integration of aptamers metal NCs, detailing molecular detection strategies that utilise effect optical signal emission NC-based biosensing systems. also highlights recent applications, well illustrative case studies. To conclude, strengths, limitations, current challenges prospects for systems were examined.

Language: Английский

Ultra-high sensitivity electrochemical aptamer biosensor based on a carbon nano-confined interface for the detection of aflatoxin B1 in traditional chinese materia medica decoction pieces DOI

B. Liu,

Long‐Yue Meng, Li Han

et al.

Carbon letters, Journal Year: 2025, Volume and Issue: unknown

Published: March 10, 2025

Language: Английский

Citations

1
Fluorescent nanosensors for detection of microbial toxins in food matrices: a review DOI

Harpreet Singh,

Dinesh Kumar,

Akash Deep

et al.

Journal of Food Measurement & Characterization, Journal Year: 2024, Volume and Issue: 18(9), P. 7669 - 7699

Published: July 27, 2024

Language: Английский

Citations

6
Leveraging Concentration Imbalance-Driven DNA Circuit as an Operational Amplifier to Enhance the Sensitivity of Hepatitis B Virus DNA Detection with Hybridization-Responsive DNA-Templated Silver Nanoclusters DOI Creative Commons

Suo Lv,

Qunyan Yao,

Jiasheng Yi

et al.

JACS Au, Journal Year: 2024, Volume and Issue: 4(6), P. 2323 - 2334

Published: May 31, 2024

Hepatitis B virus (HBV) infection remains a major global health concern, necessitating the development of sensitive and reliable diagnostic methods. In this study, we propose novel approach to enhance sensitivity HBV DNA detection by leveraging concentration imbalance-driven circuit (CIDDC) as an operational amplifier, coupled with hybridization-responsive DNA-templated silver nanocluster (DNA-AgNCs) nanoprobe named Q·C6-AgNCs. The CIDDC system effectively converts amplifies input into enriched generic single-stranded output, which subsequently triggers fluorescence DNA-AgNCs reporter upon hybridization, generating measurable signal for detection. By incorporating circuit, not only achieved enhanced lower limit 0.11 nM but also demonstrated high specificity single-base mismatch discriminability Additionally, mix-and-detect assay format is simple, user-friendly, isothermal. This innovative strategy holds promise advancing molecular diagnostics facilitating effective management HBV-related diseases.

Language: Английский

Citations

4
A fluorescent aptasensor for kanamycin detection in milk, seafood and water samples using DNA-AgNCs and exonuclease I-assisted recycling amplification strategy DOI
Dong Xu, Lei Shan,

Guo Bei

et al.

Food Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 143291 - 143291

Published: Feb. 1, 2025

Language: Английский

Citations

0
Emerging applications of biorecognition elements-based optical biosensors for food safety monitoring DOI Creative Commons
Oluwafemi Bamidele Daramola, Richard Kolade Omole, Bolanle Adenike Akinsanola

et al.

Published: Feb. 14, 2025

Language: Английский

Citations

0
A Ratiometric Fluorescence Detection Method for Berberine Using Triplex-Containing DNA-Templated Silver Nanoclusters DOI Open Access

Ming Zhu,

Mingyang Sun, Juntong Liu

et al.

Published: June 17, 2024

Berberine (BBR), as a natural isoquinoline alkaloid, has been demonstrated various pharmacological activities, and widely applied in the treatment of diseases. The quantitative analysis BBR is important for its researches clinical applications. In work, utilizing specific interaction between triplex DNA, sensitive selective fluorescent detecting method was established with DNA-templated silver nanoclusters (DNA-AgNCs). After binding structure template DNA-AgNCs, quenched fluorescence DNA-AgNCs formed BBR-triplex complex yellow-green fluorescence. ratiometric signal showed linear relationship concentration range 10 nM to 1000 nM, detect limit nM. Our exhibited excellent sensitivity selectivity, it further detection real samples.

Language: Английский

Citations

1
DNA-Templated Fluorescent Metal Nanoclusters and Their Illuminating Applications DOI
Ashwin Rajeev, Dhiraj Bhatia

Nanoscale, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

After the discovery of DNA during mid-20 th century, a multitude novel methodologies have surfaced which exploit for its various properties.

Language: Английский

Citations

1
A Ratiometric Fluorescence Detection Method for Berberine Using Triplex-Containing DNA-Templated Silver Nanoclusters DOI Creative Commons
Ming Zhu, Mingyang Sun, Juntong Liu

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(15), P. 3459 - 3459

Published: July 24, 2024

Berberine (BBR), as a natural isoquinoline alkaloid, has demonstrated various pharmacological activities, and is widely applied in the treatment of diseases. The quantitative analysis BBR important for studies clinical applications. In this work, utilizing specific interaction between triplex DNA, sensitive selective fluorescent detecting method was established with DNA-templated silver nanoclusters (DNA-AgNCs). After binding structure template DNA-AgNCs, quenched fluorescence DNA-AgNCs formed BBR-triplex complex yellow-green fluorescence. ratiometric signal showed linear relationship concentration range from 10 nM to 1000 nM, detection limit nM. Our exhibited excellent sensitivity selectivity, further real samples.

Language: Английский

Citations

0
Recent Advances of Strategies and Applications in Aptamer-Combined Metal Nanocluster Biosensing Systems DOI Creative Commons

K. H. Kim,

Sang-Ho Kim,

Seung Min Yoo

et al.

Biosensors, Journal Year: 2024, Volume and Issue: 14(12), P. 625 - 625

Published: Dec. 18, 2024

Metal nanoclusters (NCs) are promising alternatives to organic dyes and quantum dots. These NCs exhibit unique physical chemical properties, such as fluorescence, chirality, magnetism catalysis, which contribute significant advancements in biosensing, biomedical diagnostics therapy. Through adjustments composition, size, environments surface ligands, it is possible create with tunable optoelectronic catalytic activity. This review focuses on the integration of aptamers metal NCs, detailing molecular detection strategies that utilise effect optical signal emission NC-based biosensing systems. also highlights recent applications, well illustrative case studies. To conclude, strengths, limitations, current challenges prospects for systems were examined.

Language: Английский

Citations

0