Phytochemistry, Год журнала: 2024, Номер 222, С. 114076 - 114076
Опубликована: Апрель 1, 2024
Язык: Английский
TrAC Trends in Analytical Chemistry, Год журнала: 2023, Номер 167, С. 117266 - 117266
Опубликована: Сен. 1, 2023
Язык: Английский
Процитировано
32
Deleted Journal, Год журнала: 2023, Номер 13(1), С. 27 - 49
Опубликована: Апрель 14, 2023
Polymethoxyflavones (PMFs) are a type of uncommon dietary flavonoids, characterized by more than one methoxy group, which exist in limited plant species, like Citrus species and Kaempferia parviflora. In addition, different PMFs, such as nobiletin, sinensetin, tangeretin, casticin, have been isolated from these natural sources. PMFs received increasing attention due to their multiple bioactivities, antioxidant, anti-inflammatory, anti-cancer, metabolic regulatory, immunoregulatory, neuroprotective, skin protective effects. These bioactivities should be associated with the regulation critical molecular targets interaction gut microbiota. order provide comprehensive updated review sources, refined extraction, biosynthesis, metabolism, summarised discussed, emphasis on mechanisms regulating chronic diseases. Overall, may promising flavonoids forefront nutraceuticals for prevention and/or treatment certain human
Язык: Английский
Процитировано
28
ChemEngineering, Год журнала: 2024, Номер 8(4), С. 64 - 64
Опубликована: Июнь 21, 2024
The increasing global focus on green nanotechnology research has spurred the development of environmentally and biologically safe applications for various nanomaterials. Nanotechnology involves crafting diverse nanoparticles in terms shapes sizes, with a particular emphasis friendly synthesis routes. Among these, biogenic approaches, including plant-based synthesis, are favored their safety, simplicity, sustainability. Silver nanoparticles, particular, have garnered significant attention due to exceptional effectiveness, biocompatibility, eco-friendliness. Cannabis (Cannabis sativa L.) emerged as promising candidate aiding silver nanoparticles. Leveraging phytochemical constituents Cannabis, researchers successfully tailored wide array applications, spanning from biomedicine environmental remediation. This review explores properties, mechanisms, obtained Cannabis. Additionally, it delves into recent advancements techniques elucidates optical properties these By shedding light fabrication methods bionanotechnology this aims contribute growing body knowledge field nanotechnology. Through comprehensive examination processes, mechanistic aspects, potential underscores importance sustainable approaches nanoparticle highlights Cannabis-derived addressing societal challenges.
Язык: Английский
Процитировано
14
The Canadian Journal of Chemical Engineering, Год журнала: 2025, Номер unknown
Опубликована: Янв. 19, 2025
Abstract In this study, supercritical fluid extraction (SFE) was used to extract cannabis essential oil and cannabinoids from the same matrix by changing decarboxylation conditions CO 2 density. Cannabis extracted at 90 bar 50°C (0.288 g/cm 3 density), it mainly composed of α‐pinene, eucalyptol, β‐caryophyllene, selinene. Subsequently, carried out on vegetable matter operating 105°C for 15 min and, then, 120°C 1 h. The largest cannabidiol (2.96% w/w) yield obtained when SFE performed 100 40°C (0.623 density). An effective online fractional separation compounds also SFE, since no cuticular waxes were detected in GC–MS traces products interest. Operating way, expensive, time‐consuming, polluting post‐processing steps not required, producing a ready‐to‐use market.
Язык: Английский
Процитировано
1
Molecules, Год журнала: 2023, Номер 28(6), С. 2791 - 2791
Опубликована: Март 20, 2023
Since legalization, cannabis/marijuana has been gaining considerable attention as a functional ingredient in food. ∆-9 tetrahydrocannabinol (THC), cannabidiol (CBD), and other cannabinoids are key bioactive compounds with health benefits. The oral consumption of cannabis transports much less hazardous chemicals than smoking. Nevertheless, the response to is biphasically dose-dependent (hormesis; low-dose stimulation high-dose inhibition) wide individuality responses. Thus, exact same dose preparation may be beneficial for some but toxic others. purpose this review highlight concept individual variations cannabinoids, which leads challenge establishing standard safe doses products general population. mechanisms actions, acute chronic toxicities, factors affecting responses updated. Based on literature review, we found that depends exposure (delivery route, duration, frequency, interactions food drugs), (age, sex), susceptibility (genetic polymorphisms cannabinoid receptor gene, N-acylethanolamine-hydrolyzing enzymes, THC-metabolizing epigenetic regulations). Owing responses, safest way use cannabis-containing start low, go slow, stay low.
Язык: Английский
Процитировано
22
Molecules, Год журнала: 2023, Номер 28(13), С. 4928 - 4928
Опубликована: Июнь 22, 2023
The phytochemistry of fibre hemp (Cannabis sativa L., cv. Futura 75 and Felina 32) cultivated in Lithuania was investigated. soil characteristics (conductivity, pH major elements) the cultivation field were determined. chemical composition extracts essential oils (EOs) from different plant parts determined by HPLC/DAD/TOF GC/MS techniques. Among constituents, β-caryophyllene (≤46.64%) its oxide (≤14.53%), α-pinene (≤20.25%) or α-humulene (≤11.48) EOs. Cannabidiol (CBD) a predominant compound (≤64.56%) among volatile constituents methanolic leaves inflorescences. Appreciable quantities 2-monolinolein (11.31%), methyl eicosatetraenoate (9.70%) γ-sitosterol (8.99%) detected seed extracts. octadecenyl ester hexadecenoic acid (≤31.27%), friedelan-3-one (≤21.49%), dihydrobenzofuran (≤17.07%) (14.03%) roots, collected during various growth stages. CBD quantity highest flower pentane (32.73%). amounts cannabidiolic (CBDA) up to 24.21% leaf total content tetrahydrocannabinol (THC) isomers (≤22.43%). phenolic (TPC) varied 187.9 924.7 (average means, mg/L gallic equivalent (GAE)) aqueous unshelled extracts, respectively. TPC be 321.0 (mg/L GAE) root antioxidant activity (AA) Eos tested spectrophotometric DPPH● scavenging method. AA recorded for EOs (from 15.034 35.036 mmol/L, TROLOX equivalent). In case (1.556 TROLOX) found roots at maturation stage. electrochemical (cyclic square wave voltammetry) assays correlated with TPC. hydrogen-peroxide-scavenging independent
Язык: Английский
Процитировано
17
Journal of Chromatography A, Год журнала: 2024, Номер 1733, С. 465240 - 465240
Опубликована: Авг. 8, 2024
Язык: Английский
Процитировано
8
Journal of Traditional and Complementary Medicine, Год журнала: 2023, Номер 13(6), С. 575 - 587
Опубликована: Авг. 26, 2023
Scientific evidence exists about the association between neurological diseases (i.e., Parkinson's disease, Alzheimer's amyotrophic lateral sclerosis (ALS), multiple sclerosis, depression, and memory loss) oxidative damage. The increasing worldwide incidence of such is attracting attention researchers to find palliative medications reduce symptoms promote quality life, in particular, developing countries, e.g., South America Africa. Among potential alternatives, extracts Cannabis Sativa L. are suitable for people who have disorders, spasticity, pain, nausea, resulting from as cancer arthritis. In this review, we discuss latest developments use Cannabis, its subtypes constituents, extraction methods, relevant pharmacological effects. Biomedical applications, marketed products, prospects also discussed, providing bibliometric maps scientific literature published representative countries Brazil) Africa Africa). A lack on effectiveness safety besides concerns addiction other adverse events, has led many act with caution before changing Cannabis-related regulations. Recent findings expected increase social acceptance while new technologies seem boost global cannabis market because benefits (-)-trans-delta-9-tetrahydrocannabinol (Δ9-THC) cannabidiol (CBD) been proven several studies addition general employment.
Язык: Английский
Процитировано
16
Bioorganic Chemistry, Год журнала: 2024, Номер 144, С. 107090 - 107090
Опубликована: Янв. 10, 2024
Язык: Английский
Процитировано
6
Biomolecules, Год журнала: 2023, Номер 13(5), С. 764 - 764
Опубликована: Апрель 28, 2023
is a multipurpose plant that has been used in medicine for centuries. Recently, considerable research focused on the bioactive compounds of this plant, particularly cannabinoids and terpenes. Among other properties, these exhibit antitumor effects several cancer types, including colorectal (CRC). Cannabinoids show positive treatment CRC by inducing apoptosis, proliferation, metastasis, inflammation, angiogenesis, oxidative stress, autophagy. Terpenes, such as β-caryophyllene, limonene, myrcene, have also reported to potential through induction inhibition cell angiogenesis. In addition, synergy between terpenes are believed be important factors CRC. This review focuses current knowledge about terpenoids from
Язык: Английский
Процитировано
13