Enzyme-assisted extraction of bioactive compounds from seaweeds and microalgae

TrAC Trends in Analytical Chemistry, Journal Year: 2023, Volume and Issue: 167, P. 117266 - 117266

Published: Sept. 1, 2023

Language: Английский

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Natural sources, refined extraction, biosynthesis, metabolism, and bioactivities of dietary polymethoxyflavones (PMFs)

Deleted Journal, Journal Year: 2023, Volume and Issue: 13(1), P. 27 - 49

Published: April 14, 2023

Polymethoxyflavones (PMFs) are a type of uncommon dietary flavonoids, characterized by more than one methoxy group, which exist in limited plant species, like Citrus species and Kaempferia parviflora. In addition, different PMFs, such as nobiletin, sinensetin, tangeretin, casticin, have been isolated from these natural sources. PMFs received increasing attention due to their multiple bioactivities, antioxidant, anti-inflammatory, anti-cancer, metabolic regulatory, immunoregulatory, neuroprotective, skin protective effects. These bioactivities should be associated with the regulation critical molecular targets interaction gut microbiota. order provide comprehensive updated review sources, refined extraction, biosynthesis, metabolism, summarised discussed, emphasis on mechanisms regulating chronic diseases. Overall, may promising flavonoids forefront nutraceuticals for prevention and/or treatment certain human

Language: Английский

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Green Synthesis of Silver Nanoparticles from Cannabis sativa: Properties, Synthesis, Mechanistic Aspects, and Applications

ChemEngineering, Journal Year: 2024, Volume and Issue: 8(4), P. 64 - 64

Published: June 21, 2024

The increasing global focus on green nanotechnology research has spurred the development of environmentally and biologically safe applications for various nanomaterials. Nanotechnology involves crafting diverse nanoparticles in terms shapes sizes, with a particular emphasis friendly synthesis routes. Among these, biogenic approaches, including plant-based synthesis, are favored their safety, simplicity, sustainability. Silver nanoparticles, particular, have garnered significant attention due to exceptional effectiveness, biocompatibility, eco-friendliness. Cannabis (Cannabis sativa L.) emerged as promising candidate aiding silver nanoparticles. Leveraging phytochemical constituents Cannabis, researchers successfully tailored wide array applications, spanning from biomedicine environmental remediation. This review explores properties, mechanisms, obtained Cannabis. Additionally, it delves into recent advancements techniques elucidates optical properties these By shedding light fabrication methods bionanotechnology this aims contribute growing body knowledge field nanotechnology. Through comprehensive examination processes, mechanistic aspects, potential underscores importance sustainable approaches nanoparticle highlights Cannabis-derived addressing societal challenges.

Language: Английский

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Green and selective supercritical fluid extraction of essential oil and cannabidiol from Cannabis sativa L.

The Canadian Journal of Chemical Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 19, 2025

Abstract In this study, supercritical fluid extraction (SFE) was used to extract cannabis essential oil and cannabinoids from the same matrix by changing decarboxylation conditions CO 2 density. Cannabis extracted at 90 bar 50°C (0.288 g/cm 3 density), it mainly composed of α‐pinene, eucalyptol, β‐caryophyllene, selinene. Subsequently, carried out on vegetable matter operating 105°C for 15 min and, then, 120°C 1 h. The largest cannabidiol (2.96% w/w) yield obtained when SFE performed 100 40°C (0.623 density). An effective online fractional separation compounds also SFE, since no cuticular waxes were detected in GC–MS traces products interest. Operating way, expensive, time‐consuming, polluting post‐processing steps not required, producing a ready‐to‐use market.

Language: Английский

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An Individuality of Response to Cannabinoids: Challenges in Safety and Efficacy of Cannabis Products

Molecules, Journal Year: 2023, Volume and Issue: 28(6), P. 2791 - 2791

Published: March 20, 2023

Since legalization, cannabis/marijuana has been gaining considerable attention as a functional ingredient in food. ∆-9 tetrahydrocannabinol (THC), cannabidiol (CBD), and other cannabinoids are key bioactive compounds with health benefits. The oral consumption of cannabis transports much less hazardous chemicals than smoking. Nevertheless, the response to is biphasically dose-dependent (hormesis; low-dose stimulation high-dose inhibition) wide individuality responses. Thus, exact same dose preparation may be beneficial for some but toxic others. purpose this review highlight concept individual variations cannabinoids, which leads challenge establishing standard safe doses products general population. mechanisms actions, acute chronic toxicities, factors affecting responses updated. Based on literature review, we found that depends exposure (delivery route, duration, frequency, interactions food drugs), (age, sex), susceptibility (genetic polymorphisms cannabinoid receptor gene, N-acylethanolamine-hydrolyzing enzymes, THC-metabolizing epigenetic regulations). Owing responses, safest way use cannabis-containing start low, go slow, stay low.

Language: Английский

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Phytochemical Composition and Antioxidant Activity of Various Extracts of Fibre Hemp (Cannabis sativa L.) Cultivated in Lithuania

Molecules, Journal Year: 2023, Volume and Issue: 28(13), P. 4928 - 4928

Published: June 22, 2023

The phytochemistry of fibre hemp (Cannabis sativa L., cv. Futura 75 and Felina 32) cultivated in Lithuania was investigated. soil characteristics (conductivity, pH major elements) the cultivation field were determined. chemical composition extracts essential oils (EOs) from different plant parts determined by HPLC/DAD/TOF GC/MS techniques. Among constituents, β-caryophyllene (≤46.64%) its oxide (≤14.53%), α-pinene (≤20.25%) or α-humulene (≤11.48) EOs. Cannabidiol (CBD) a predominant compound (≤64.56%) among volatile constituents methanolic leaves inflorescences. Appreciable quantities 2-monolinolein (11.31%), methyl eicosatetraenoate (9.70%) γ-sitosterol (8.99%) detected seed extracts. octadecenyl ester hexadecenoic acid (≤31.27%), friedelan-3-one (≤21.49%), dihydrobenzofuran (≤17.07%) (14.03%) roots, collected during various growth stages. CBD quantity highest flower pentane (32.73%). amounts cannabidiolic (CBDA) up to 24.21% leaf total content tetrahydrocannabinol (THC) isomers (≤22.43%). phenolic (TPC) varied 187.9 924.7 (average means, mg/L gallic equivalent (GAE)) aqueous unshelled extracts, respectively. TPC be 321.0 (mg/L GAE) root antioxidant activity (AA) Eos tested spectrophotometric DPPH● scavenging method. AA recorded for EOs (from 15.034 35.036 mmol/L, TROLOX equivalent). In case (1.556 TROLOX) found roots at maturation stage. electrochemical (cyclic square wave voltammetry) assays correlated with TPC. hydrogen-peroxide-scavenging independent

Language: Английский

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Integrated supercritical fluid extraction of essential oils

Journal of Chromatography A, Journal Year: 2024, Volume and Issue: 1733, P. 465240 - 465240

Published: Aug. 8, 2024

Language: Английский

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Phytocannabinoids: Pharmacological effects, biomedical applications, and worldwide prospection

Journal of Traditional and Complementary Medicine, Journal Year: 2023, Volume and Issue: 13(6), P. 575 - 587

Published: Aug. 26, 2023

Scientific evidence exists about the association between neurological diseases (i.e., Parkinson's disease, Alzheimer's amyotrophic lateral sclerosis (ALS), multiple sclerosis, depression, and memory loss) oxidative damage. The increasing worldwide incidence of such is attracting attention researchers to find palliative medications reduce symptoms promote quality life, in particular, developing countries, e.g., South America Africa. Among potential alternatives, extracts Cannabis Sativa L. are suitable for people who have disorders, spasticity, pain, nausea, resulting from as cancer arthritis. In this review, we discuss latest developments use Cannabis, its subtypes constituents, extraction methods, relevant pharmacological effects. Biomedical applications, marketed products, prospects also discussed, providing bibliometric maps scientific literature published representative countries Brazil) Africa Africa). A lack on effectiveness safety besides concerns addiction other adverse events, has led many act with caution before changing Cannabis-related regulations. Recent findings expected increase social acceptance while new technologies seem boost global cannabis market because benefits (-)-trans-delta-9-tetrahydrocannabinol (Δ9-THC) cannabidiol (CBD) been proven several studies addition general employment.

Language: Английский

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Decoding active compounds and molecular targets of herbal medicine by high-throughput metabolomics technology: A systematic review

Bioorganic Chemistry, Journal Year: 2024, Volume and Issue: 144, P. 107090 - 107090

Published: Jan. 10, 2024

Language: Английский

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Antitumor Effects of Cannabis sativa Bioactive Compounds on Colorectal Carcinogenesis

Biomolecules, Journal Year: 2023, Volume and Issue: 13(5), P. 764 - 764

Published: April 28, 2023

is a multipurpose plant that has been used in medicine for centuries. Recently, considerable research focused on the bioactive compounds of this plant, particularly cannabinoids and terpenes. Among other properties, these exhibit antitumor effects several cancer types, including colorectal (CRC). Cannabinoids show positive treatment CRC by inducing apoptosis, proliferation, metastasis, inflammation, angiogenesis, oxidative stress, autophagy. Terpenes, such as β-caryophyllene, limonene, myrcene, have also reported to potential through induction inhibition cell angiogenesis. In addition, synergy between terpenes are believed be important factors CRC. This review focuses current knowledge about terpenoids from

Language: Английский

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