Chemical Engineering Journal, Год журнала: 2024, Номер 499, С. 156497 - 156497
Опубликована: Окт. 11, 2024
Язык: Английский
Sensors, Год журнала: 2024, Номер 24(16), С. 5143 - 5143
Опубликована: Авг. 8, 2024
This comprehensive review delves into the forefront of biosensor technologies and their critical roles in disease biomarker detection therapeutic drug monitoring. It provides an in-depth analysis various types applications, including enzymatic sensors, immunosensors, DNA elucidating mechanisms specific healthcare applications. The highlights recent innovations such as integrating nanotechnology, developing wearable devices, trends miniaturisation, showcasing transformative potential healthcare. In addition, it addresses significant sensitivity, specificity, reproducibility, data security challenges, proposing strategic solutions to overcome these obstacles. is envisaged that will inform decision-making, drive technological innovation, enhance global outcomes by synthesising multidisciplinary insights.
Язык: Английский
Процитировано
18
Chemosensors, Год журнала: 2023, Номер 11(7), С. 388 - 388
Опубликована: Июль 12, 2023
Neurotransmitters (NTs) play a crucial role in regulating the behavioral and physiological functions of nervous system. Imbalances concentrations NT have been directly linked to various neurological diseases (e.g., Parkinson’s, Huntington’s, Alzheimer’s disease), addition multiple psychotic disorders such as schizophrenia, depression, dementia, other neurodegenerative disorders. Hence, rapid real-time monitoring NTs is utmost importance comprehending identifying Among different sensing techniques, electrochemical biosensors garnered significant interest due their ability deliver fast results, compatibility for miniaturization portability, high sensitivity, good controllability. Furthermore, utilization enzymes recognition elements biosensing design has renewed attention unique advantages catalytic biorecognition coupled with simultaneous signal amplification. This review paper primarily focuses on covering recent advances enzymatic detection NTs, encompassing sensors, electrode materials, electroanalytical techniques. Moreover, we shed light applications enzyme-based complex matrices vivo monitoring. Despite numerous biosensors, there are still challenges that need be addressed, which thoroughly discussed this paper. Finally, also presents an outlook future perspectives opportunities development detection.
Язык: Английский
Процитировано
23
Nanoscale Horizons, Год журнала: 2023, Номер 8(12), С. 1610 - 1627
Опубликована: Янв. 1, 2023
This review provides an overview of the fundamentals microfluidic reactors and summarizes their use for fabricating various nanomaterials applications in biomedical field.
Язык: Английский
Процитировано
22
Small, Год журнала: 2024, Номер 20(43)
Опубликована: Июнь 28, 2024
Abstract For every epidemic outbreak, the prevention and treatments in resource‐limited areas are always out of reach. Critical to this is that high accuracy, stability, more comprehensive analytical techniques rely on expensive bulky instruments large laboratories. Here, a fully integrated high‐throughput microfluidic system proposed for ultra‐multiple point‐of‐care immunoassay, termed Dac system. Specifically, only requires handheld portable device automatically recycle repetitive multi‐step reactions including on‐demand liquid releasing, dispensing, metering, collecting, oscillatory mixing, discharging. The performs high‐precision enzyme‐linked immunosorbent assays up 17 samples or targets simultaneously single chip. Furthermore, reagent consumption 2% compared conventional ELISA, microbubble‐accelerated shorten assay time by than half. As proof concept, multiplexed detections achieved detecting at least four infection two singular barcode‐based multi‐target results can rapidly distinguish between five similar cases, allowing accurate therapeutic interventions. Compared clinical instruments, accuracy inflammation classification 92.38% ( n = 105), with quantitative correlation coefficient R 2 0.9838, while specificity 100% sensitivity 98.93%.
Язык: Английский
Процитировано
12
Food Chemistry, Год журнала: 2024, Номер 441, С. 138319 - 138319
Опубликована: Янв. 2, 2024
Язык: Английский
Процитировано
11
Materials Today Bio, Год журнала: 2024, Номер 26, С. 101048 - 101048
Опубликована: Апрель 4, 2024
Biosensing is vital for many areas like disease diagnosis, infectious prevention, and point-of-care monitoring. Microfluidics has been evidenced to be a powerful tool biosensing via integrating biological detection processes into palm-size chip. Based on the chip structure, microfluidics two subdivision types: open closed microfluidics, whose operation methods would diverse. In this review, we summarize fundamentals, liquid control methods, applications of separately, point out bottlenecks, propose potential directions microfluidics-based biosensing.
Язык: Английский
Процитировано
8
Lab on a Chip, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Centrifugal microfluidics, with its advantages of rapid and precise fluid control without the need for external pressure, is widely applied in point-of-care testing.
Язык: Английский
Процитировано
1
Chemical Engineering Journal, Год журнала: 2025, Номер unknown, С. 159741 - 159741
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
1
Analytica Chimica Acta, Год журнала: 2025, Номер 1351, С. 343883 - 343883
Опубликована: Март 5, 2025
Язык: Английский
Процитировано
1
TrAC Trends in Analytical Chemistry, Год журнала: 2023, Номер 162, С. 117029 - 117029
Опубликована: Март 21, 2023
Язык: Английский
Процитировано
16