Infectious Disease Clinics of North America, Год журнала: 2023, Номер 37(4), С. 669 - 681
Опубликована: Авг. 20, 2023
Язык: Английский
npj Antimicrobials and Resistance, Год журнала: 2024, Номер 2(1)
Опубликована: Май 2, 2024
Antimicrobial stewardship (AMS) is a commonly advocated approach to address antimicrobial resistance. However, AMS often defined in different ways depending on where it applied, such that range of definitions now use. These may be functional and well-structured for given context but are ill-adapted collaborative work, creating difficulties intersectoral communication complicating the design, implementation, evaluation interventions from One Health perspective. Using boundary object theory, we identified three key elements common settings human animal health sectors-a sense collective temporal responsibility, flexibility scale scope, contextual contingency. Based these findings, propose definition applicable sectors, intended facilitate cooperation. Further directions this work could include application develop indicators evaluating extension incorporate pertinent plant ecosystem health.
Язык: Английский
Процитировано
12
Pharmacology & Pharmacy, Год журнала: 2024, Номер 15(04), С. 81 - 112
Опубликована: Янв. 1, 2024
Background: Antifungal resistance (AFR) is a global public health problem with devastating effects, especially among immunocompromised individuals. Addressing AFR requires One Health approach including Stewardship (AFS). This study aimed to comprehensively review studies published on fungal infections and recommend solutions address this growing problem. Materials Methods: was narrative that conducted using papers infections, AFR, AFS between January 1961 March 2024. The literature searched PubMed, Google Scholar, Web of Science, EMBASE. Results: found there has been an increase in globally, patients. Due proportionate the use antifungal agents prevent treat infections. increased worsened contributing morbidity mortality. Globally, have contributed 150 million annually 1.7 deaths per year. By year 2023, over 3.8 people died from remains challenge because treatment antifungal-resistant difficult. Finally, exacerbated by limited number invasive Conclusion: results indicated are prevalent across humans, animals, agriculture, environment. provision such as improving awareness conducting further research discovery new agents, implementing programs. If not addressed, mortality associated will continue rise future.
Язык: Английский
Процитировано
10
Infection Prevention in Practice, Год журнала: 2023, Номер 5(4), С. 100315 - 100315
Опубликована: Ноя. 14, 2023
Язык: Английский
Процитировано
17
Pharmacology & Pharmacy, Год журнала: 2024, Номер 15(12), С. 403 - 465
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
7
Antibiotics, Год журнала: 2025, Номер 14(3), С. 264 - 264
Опубликована: Март 5, 2025
With nearly half of colorectal cancer (CRC) patients diagnosed at advanced stages where surgery alone is insufficient, chemotherapy remains a cornerstone for this treatment. To prevent infections and improve outcomes, antibiotics are often co-administered. However, chemotherapeutic interactions with the gut microbiota cause significant non-selective toxicity, affecting not only tumor normal epithelial cells but also microbiota. This toxicity triggers bacterial SOS response loss microbial diversity, leading to mutations dysbiosis. Consequently, pathogenic overgrowth systemic increase, necessitating broad-spectrum intervention. review underscores how prolonged antibiotic use during chemotherapy, combined chemotherapy-induced mutations, creates selective pressures that drive de novo antimicrobial resistance (AMR), allowing resistant bacteria dominate gut. compromises treatment efficacy elevates mortality risk. Restoring diversity may mitigate therapeutic emerging strategies, such as fecal transplantation (FMT), probiotics, prebiotics, show considerable promise. Given global threat posed by treatment, prioritizing stewardship essential optimizing preventing in CRC undergoing chemotherapy. Future research should aim minimize chemotherapy’s impact on develop targeted interventions restore affected
Язык: Английский
Процитировано
0
Family Practice, Год журнала: 2025, Номер 42(2)
Опубликована: Фев. 7, 2025
Antimicrobial resistance (AMR) is a global health warning that increases mortality, morbidity, and medical expenses. Effective AMR surveillance essential to guide interventions maintain treatment efficacy. While studied in various healthcare settings, data sources primary care settings need be evaluated. To identify the value of utilizing inform community antimicrobial stewardship (AMS) practices. Eligibility criteria included studies, randomized nonrandomised controlled trials, observational surveys, qualitative mixed-method grey literature published worldwide from 2001 2024. Our review 21 studies emphasized significance enhance clinical care. Clinicians better understand local pattern when prescribing antibiotics. Despite limitations, educational can change behaviour. increased because susceptibility frequently did not empirical antibiotic treatment. Digital geospatial platforms could with institutional support standardized integration. This analysis highlights for user-friendly, real-time, easily accessible visualization improve AMS Addressing accessibility providing training education are crucial elements. Standardising digital technologies decision-making prescribing. These elements must incorporated into consistent adaptive plan effective public outcomes.
Язык: Английский
Процитировано
0
Clinical Microbiology Newsletter, Год журнала: 2025, Номер unknown
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0
Infection and Chemotherapy, Год журнала: 2024, Номер 56(4), С. 555 - 555
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
1
Journal of Clinical Medicine, Год журнала: 2024, Номер 13(13), С. 3740 - 3740
Опубликована: Июнь 26, 2024
Background/Objective: Clostridioides difficile infection (CDI) is a common healthcare-associated ailment, presenting major health and economic challenges, especially for the elderly. Despite its prevalence, comprehensive data about CDI's impact on elderly are limited. Methods: This study used Global Burden of Disease Study 2019 to analyze CDI trends from 2000 2019, considering factors like sex, region, sociodemographic index (SDI). Results: revealed that caused approximately 18,181 deaths 252,709 disability-adjusted life years (DALYs) among worldwide. The Americas showed highest burden, while Eastern Mediterranean saw steepest rate increase 2019. Regions with high SDI also displayed substantial impact. Conclusions: escalating burden in elderly, high-SDI areas Americas, emphasizes an urgent need targeted public strategies.
Язык: Английский
Процитировано
0
Infectious Disease Clinics of North America, Год журнала: 2023, Номер 37(4), С. 669 - 681
Опубликована: Авг. 20, 2023
Язык: Английский
Процитировано
0