Journal of the American Chemical Society,
Год журнала:
2021,
Номер
143(4), С. 1699 - 1721
Опубликована: Янв. 19, 2021
A
growing
number
of
organopnictogen
redox
catalytic
methods
have
emerged-especially
within
the
past
10
years-that
leverage
plentiful
reversible
two-electron
chemistry
Group
15.
The
goal
this
Perspective
is
to
provide
readers
context
understand
dramatic
developments
in
catalysis
over
decade
with
an
eye
toward
future
development.
An
exposition
fundamental
differences
atomic
structure
and
bonding
pnictogens,
thus
molecular
electronic
compounds,
presented
establish
backdrop
against
which
reactivity-and
ultimately
catalysis-is
framed.
deep
appreciation
these
underlying
periodic
principles
informs
understanding
differing
modes
evokes
key
challenges
field
moving
forward.
We
close
by
addressing
forward-looking
directions
likely
animate
area
years
come.
What
new
manifolds
can
be
developed
through
creative
catalyst
reaction
design
that
take
advantage
intrinsic
reactivity
pnictogens
drive
discoveries
catalysis?
Chemical Society Reviews,
Год журнала:
2018,
Номер
47(15), С. 5786 - 5865
Опубликована: Янв. 1, 2018
This
review
provides
an
overview
of
the
use
electrochemistry
as
appealing
platform
for
expediting
carbon–hydrogen
functionalization
and
carbon–nitrogen
bond
formation.
Chemical Reviews,
Год журнала:
2021,
Номер
122(2), С. 1875 - 1924
Опубликована: Авг. 6, 2021
Direct
photocatalyzed
hydrogen
atom
transfer
(d-HAT)
can
be
considered
a
method
of
choice
for
the
elaboration
aliphatic
C–H
bonds.
In
this
manifold,
photocatalyst
(PCHAT)
exploits
energy
photon
to
trigger
homolytic
cleavage
such
bonds
in
organic
compounds.
Selective
bond
may
achieved
by
judicious
abstractor
(key
parameters
are
electronic
character
and
molecular
structure),
as
well
reaction
additives.
Different
classes
PCsHAT
available,
including
aromatic
ketones,
xanthene
dyes
(Eosin
Y),
polyoxometalates,
uranyl
salts,
metal-oxo
porphyrin
tris(amino)cyclopropenium
radical
dication.
The
processes
(mainly
C–C
formation)
most
cases
carried
out
under
mild
conditions
with
help
visible
light.
aim
review
is
offer
comprehensive
survey
synthetic
applications
d-HAT.
Angewandte Chemie International Edition,
Год журнала:
2018,
Номер
58(12), С. 3730 - 3747
Опубликована: Окт. 19, 2018
Abstract
The
fast‐moving
fields
of
photoredox
and
photocatalysis
have
recently
provided
fresh
opportunities
to
expand
the
potential
synthetic
organic
chemistry.
Advances
in
light‐mediated
processes
mainly
been
guided
so
far
by
empirical
findings
quest
for
reaction
invention.
general
perception,
however,
is
that
entering
a
more
mature
phase
where
combination
experimental
mechanistic
studies
will
play
dominant
role
sustaining
further
innovation.
This
Review
outlines
key
consider
when
developing
photochemical
process,
best
techniques
available
acquiring
relevant
information.
discussion
use
selected
case
highlight
how
investigations
can
be
instrumental
guiding
invention
development
synthetically
useful
photocatalytic
transformations.
Chemical Reviews,
Год журнала:
2017,
Номер
117(13), С. 9433 - 9520
Опубликована: Фев. 13, 2017
As
two
coexisting
and
fast-growing
research
fields
in
modern
synthetic
chemistry,
the
merging
of
organocatalysis
C–H
bond
functionalization
is
well
foreseeable,
joint
force
along
this
line
has
been
demonstrated
to
be
a
powerful
approach
making
inert
more
viable,
predictable,
selective.
In
review,
we
provide
comprehensive
summary
over
past
decades.
The
review
arranged
by
types
bonds
including
alkane
C–H,
arene
vinyl
as
those
activated
benzylic
allylic
alpha
heteroatom
such
nitrogen
oxygen.
each
section,
discussion
classified
explicit
organocatalytic
mode
involved.
Angewandte Chemie International Edition,
Год журнала:
2019,
Номер
58(39), С. 13666 - 13699
Опубликована: Март 20, 2019
Abstract
Reactions
that
involve
the
addition
of
carbon‐centered
radicals
to
basic
heteroarenes,
followed
by
formal
hydrogen
atom
loss,
have
become
widely
known
as
Minisci‐type
reactions.
First
developed
into
a
useful
synthetic
tool
in
late
1960s
Minisci,
this
reaction
type
has
been
constant
use
over
last
half
century
chemists
seeking
functionalize
heterocycles
rapid
and
direct
manner,
avoiding
need
for
de
novo
heterocycle
synthesis.
Whilst
originally
protocols
radical
generation
remain
active
today,
they
joined
recent
years
new
array
strategies
allow
wider
variety
precursors
often
operate
under
milder
more
benign
conditions.
The
surge
interest
transformations
based
on
free
reactivity
meant
numerous
choices
are
now
available
chemist
looking
utilize
reaction.
Radical‐generation
methods
photoredox
catalysis
electrochemistry
approaches
which
thermal
cleavage
or
situ
reactive
precursors.
This
review
will
cover
remarkably
large
body
literature
appeared
topic
decade
an
attempt
provide
guidance
chemist,
well
perspective
both
challenges
overcome
those
still
remain.
As
logical
classification
advances
nature
precursor,
with
most
concerned,
control
various
selectivity
aspects
associated
reactions
also
be
discussed.
ACS Catalysis,
Год журнала:
2017,
Номер
7(4), С. 2563 - 2575
Опубликована: Март 14, 2017
Photoredox
catalysis
has
experienced
a
revitalized
interest
from
the
synthesis
community
during
past
decade.
For
example,
photoredox/Ni
dual
protocols
have
been
developed
to
overcome
several
inherent
limitations
of
palladium-catalyzed
cross-couplings
by
invoking
single-electron
transmetalation
pathway.
This
Perspective
highlights
advances
made
our
laboratory
since
inception
cross-coupling
benzyltrifluoroborates
with
aryl
bromides.
In
addition
broadening
scope
trifluoroborate
coupling
partners,
research
using
readily
oxidized
hypervalent
silicates
as
radical
precursors
that
demonstrate
functional
group
compatibility
is
highlighted.
The
pursuit
electrophilic
partners
beyond
(hetero)aryl
bromides
also
led
incorporation
new
classes
C(sp2)-hybridized
substrates
into
light-mediated
cross-coupling.
Advances
expand
toolbox
utilizing
feedstock
chemicals
(e.g.,
aldehydes)
access
radicals
were
previously
inaccessible
trifluoroborates
and
are
emphasized.
Additionally,
organic
photocatalysts
investigated
replacements
for
their
expensive
iridium-
ruthenium-based
counterparts.
Lastly,
net
C–H
functionalization
partner
in
an
effort
improve
atom
economy
presented.
An
underlying
theme
all
these
studies
value
generating
catalytic
manner,
rather
than
stoichiometrically.
Chemical Reviews,
Год журнала:
2021,
Номер
122(2), С. 2752 - 2906
Опубликована: Авг. 10, 2021
Photoinduced
chemical
transformations
have
received
in
recent
years
a
tremendous
amount
of
attention,
providing
plethora
opportunities
to
synthetic
organic
chemists.
However,
performing
photochemical
transformation
can
be
quite
challenge
because
various
issues
related
the
delivery
photons.
These
challenges
barred
widespread
adoption
steps
industry.
past
decade,
several
technological
innovations
led
more
reproducible,
selective,
and
scalable
photoinduced
reactions.
Herein,
we
provide
comprehensive
overview
these
exciting
advances,
including
flow
chemistry,
high-throughput
experimentation,
reactor
design
scale-up,
combination
photo-
electro-chemistry.
Oxidative Medicine and Cellular Longevity,
Год журнала:
2020,
Номер
2020, С. 1 - 13
Опубликована: Март 9, 2020
Type
2
diabetes
mellitus
(T2DM)
is
the
most
prevalent
metabolic
disorder
characterized
by
chronic
hyperglycemia
and
an
inadequate
response
to
circulatory
insulin
peripheral
tissues
resulting
in
resistance.
Insulin
resistance
has
a
complex
pathophysiology,
it
contributed
multiple
factors
including
oxidative
stress.
Oxidative
stress
refers
imbalance
between
free
radical
production
antioxidant
system
leading
reduction
of
sensitivity
contributing
development
T2DM
via
several
molecular
mechanisms.
In
this
review,
we
present
mechanisms
which
milieu
contributes
pathophysiology
mellitus.
Chemical Society Reviews,
Год журнала:
2020,
Номер
49(17), С. 6198 - 6223
Опубликована: Янв. 1, 2020
This
review
highlights
recent
advances
in
photocatalytic
transformations
of
lignocellulosic
biomass
(polysaccharides
and
lignin)
into
chemicals
(in
particular
organic
oxygenates).
