Environmental Science & Technology,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 25, 2025
The
western
mosquitofish
(Gambusia
affinis
(G.
affinis))
is
often
the
only
fish
that
survives
in
various
selenium-contaminated
aquatic
environments.
However,
mechanisms
of
its
survival
such
environments
remain
seldom
explored.
In
this
study,
acute
toxicity
selenomethionine
(Se-Met)
a
variety
species
(four
oviparous
and
four
ovoviviparous
species)
was
evaluated,
followed
by
chronic
effects
Se-Met
on
G.
zebrafish
(Danio
rerio
(D.
rerio)),
focusing
Se
accumulation
gonads
offspring,
reproductive
biology,
offspring
development.
Our
results
showed
LC50-96h
largest
among
eight
fish,
confirming
elevated
resistance
to
Se.
Meanwhile,
transcripts
genes
related
selenoproteins
sulfoproteins
opposite
responses
between
D.
exposure,
along
with
altered
levels
total
but
not
fish.
exposures
gonads,
gonadal
development
embryonic
early
larval
development,
efflux
embryos
larvae
were
apparently
different
rerio.
Finally,
differentially
expressed
(particularly
antioxidant
inflammation)
mostly
stimulated
inhibited
This
study
has
demonstrated
capacity
metabolism
physiology
can
help
partially
explain
Se-contaminated
ecosystems.
Environmental Science & Technology,
Год журнала:
2021,
Номер
55(24), С. 16515 - 16525
Опубликована: Дек. 7, 2021
Excess
dietary
seleno-l-methionine
(Se-Met)
induces
various
adverse
effects
in
fish
inhabiting
the
Se-contaminated
environments.
However,
there
is
an
extreme
paucity
of
data
on
excess
Se-Met
microbiota
gastrointestinal
(GI)
tract
fish.
In
this
study,
Japanese
medaka
Oryzias
latipes
(three
months
old)
were
fed
enriched
diets
at
environmentally
relevant
concentrations:
2.90
(Control:
(C),
6.69
(L),
11.89
(M),
and
27.05
(H)
μg
Se/g
dw)
for
60
d.
Histopathological,
high
throughput
sequencing,
biochemical
approaches
used
to
investigate
alterations
histology
microbial
communities
GI
tract,
enzymatic
activity,
transcripts
closely
related
genes.
The
results
showed
that
weight
was
reduced
∼13%
from
L
H
treatments.
Decreased
height
thickness
villus
observed
treatment.
Meanwhile,
level
D-lactate
activity
diamine
oxidase
(DAO),
protease,
lipase
inhibited
genes
inflammation
(i.e.,
IL-1β
IL-8)
elevated,
while
those
intestinal
barrier
cdh1,
ZO-1,
ocln,
cldn7)
addition,
alpha
diversity
genus
higher
treatment
than
control,
composition
community
altered
by
Se-Met.
Furthermore,
5
genera
(Rhodobacter,
Cloacibacterium,
Bdellovibrio,
Shinella,
Aeromonas)
exhibited
largest
variation
abundance
among
This
study
has
demonstrated
inhibits
growth,
causes
hispathological
damage
alters
latipes.
Ecotoxicology and Environmental Safety,
Год журнала:
2022,
Номер
245, С. 114119 - 114119
Опубликована: Сен. 26, 2022
Cyanobacterial
harmful
algal
blooms
(cHABs)
pose
a
risk
to
exposed
aquatic
and
terrestrial
species.
Numerous
studies
have
addressed
effects
of
single
toxins
while
much
less
attention
has
been
devoted
mixtures
cHAB
metabolites
that
are
continually
released
by
living
cyanobacteria.
Neuro-impairment
associated
with
cHABs
reported
in
fish,
though
the
mechanism
remains
unclear.
Here
we
embryos
Sinocyclocheilus
grahami,
an
endangered
Microcystis
aeruginosa
exudates
(MaE)
evaluate
neurotoxicity
toxicity
mechanism(s).
We
found
MaE
affected
embryonic
development
increasing
malformation
mortality
rates
decreasing
fertilization
rate.
also
inhibited
fish
neurobehavior
including
touch
response,
social
frequency,
swimming
distance,
aggravated
light-stimulation
response.
Neurobehavior
suppression
resulted
from
decrease
excitatory
neurotransmitters
acetylcholine
dopamine,
even
receptors
increased.
gene
protein
expression
neurotransmitters,
synthetic
and/or
degrading
enzymes,
receptors.
Our
findings
shed
light
on
specific
mechanisms
which
induces
early
life
stages
contributes
improvement
conservation
strategy
for
this
International Journal of Biological Macromolecules,
Год журнала:
2022,
Номер
222, С. 1037 - 1047
Опубликована: Сен. 29, 2022
A
56-day
feeding
trial
was
conducted
to
assess
the
effects
of
different
viscous
guar
gum
on
growth,
intestinal
flora,
and
health
Micropterus
salmoides.
Four
practical
diets
with
42.5
%
crude
protein
13.7
lipid
were
formulated
contain
8
cellulose
three
viscosities
(2500,
5200,
6000
mPa·s)
gum.
Dietary
inhibits
fish
growth
feed
utilization,
decreases
α-diversity
negatively
alters
flora
structure
metabolite
composition.
High
down-regulated
tight
junction,
anti-inflammatory,
anti-apoptotic
related
gene's
expression,
decreased
digesta
butyrate/histamine
ratio;
increased
abundance
Plesiomonas
shigelloides.
These
results
suggest
that
dietary
adversely
affects
by
disrupting
composition,
viscosity
should
be
considered
when
using
as
a
binder
in
aquafeeds.
Toxicology Research,
Год журнала:
2024,
Номер
13(2)
Опубликована: Март 1, 2024
Selenium
is
an
important
and
essential
trace
element
in
organisms,
but
its
effects
on
organisms
are
also
a
"double-edged
sword".
deficiency
or
excess
can
endanger
the
health
of
humans
animals.
In
order
to
thoroughly
understand
nutritional
value
toxicity
hazards
selenium,
researchers
have
conducted
many
studies
model
animal
zebrafish.
However,
there
lack
induction
summary
relevant
research
which
selenium
acts
This
paper
provides
review
reported
studies.
Firstly,
this
article
summarizes
benefits
zebrafish
from
three
aspects:
Promoting
growth,
Enhancing
immune
function
anti-tumor
ability,
Antagonizing
some
pollutants,
such
as
mercury.
Then,
aspects
introduced:
nervous
system
behavior,
reproductive
damage
organs.
describes
how
different
forms
compounds
health.
Finally,
prospects
for
future
directions
presented.
