Microplastics in the human body: A comprehensive review of exposure, distribution, migration mechanisms, and toxicity

The Science of The Total Environment, Год журнала: 2024, Номер 946, С. 174215 - 174215

Опубликована: Июнь 22, 2024

Язык: Английский

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Combined toxicity of polystyrene microplastics and perfluorobutane sulfonate on mouse liver: Impact on lipid metabolism and gut-liver axis disruption

Ecotoxicology and Environmental Safety, Год журнала: 2025, Номер 292, С. 117904 - 117904

Опубликована: Фев. 20, 2025

Язык: Английский

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New insight into intestinal toxicity accelerated by aged microplastics with triclosan: inflammation regulation by gut microbiota-bile acid axis

Journal of Hazardous Materials, Год журнала: 2025, Номер 492, С. 138308 - 138308

Опубликована: Апрель 15, 2025

Язык: Английский

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Toxicity enhancement of microplastics released from food containers through thermal aging: Absorbing more serum proteins thus activating the innate immune response via actin polymerization

Environment International, Год журнала: 2025, Номер 197, С. 109358 - 109358

Опубликована: Март 1, 2025

This study examined the effects of hot high-fat simulants on physicochemical properties microplastics (MPs) from polypropylene (PP)-, low-density polyethylene (LDPE)-, and polylactic acid (PLA)-based single-use food container (SUFC) leachates those aging their immunomodulatory effectors. Scenario studies have demonstrated that MPs were released these three types SUFCs. LDPE- PLA-based SUFCs also cellulose. Among SUFCs, only PP particles exhibited a new absorption peak at 1725 cm-1, which phenomenon may be attributed to presence unstable tertiary carbon atoms. Subsequently, we investigated removing additive both thermal-aged with polystyrene (PS) carboxyl-modified PS (PS-COOH) polymer backbones as reference materials. The findings indicated PS-COOH induced comparable innate immune responses, exhibiting similar size SUFC percolates. Consequently, selected original MPs, respectively, evaluate immunity. results revealed thata protein corona formed particle types, more adsorption observed particles. complex enhanced phagocytosis RAW264.7 macrophages increased expression pro-inflammatory genes NOS2 TNF-α through an actin polymerization cross-linking mechanism. In this study, how affect responses using model system, emphasizing importance comprehensive safety evaluations MPs.

Язык: Английский

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The role of gut microbiota in MP/NP-induced toxicity

Environmental Pollution, Год журнала: 2024, Номер 359, С. 124742 - 124742

Опубликована: Авг. 15, 2024

Язык: Английский

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Photoaged tire wear particles hinder the transport of Pb(II) in urban soils under acid rain: Experimental and numerical Investigations

Water Research, Год журнала: 2024, Номер 266, С. 122410 - 122410

Опубликована: Сен. 7, 2024

Язык: Английский

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Tire-wear particle leachate at environmentally relevant concentrations exert a hepatotoxic impact on the black-spotted frog by disrupting the gut–liver axis

Environmental Chemistry and Ecotoxicology, Год журнала: 2024, Номер 6, С. 380 - 389

Опубликована: Янв. 1, 2024

Язык: Английский

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Links between fecal microplastics and parameters related to metabolic dysfunction-associated steatotic liver disease (MASLD) in humans: An exploratory study

The Science of The Total Environment, Год журнала: 2024, Номер 953, С. 176153 - 176153

Опубликована: Сен. 10, 2024

Язык: Английский

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Microplastics on the Planet: Current Knowledge and Challenges

Environmental Science & Technology Letters, Год журнала: 2024, Номер 11(12), С. 1262 - 1271

Опубликована: Ноя. 25, 2024

Microplastic (MP) pollution has become a global issue, attracting attention from stakeholders around the globe. Knowledge of MPs been substantially advanced in recent years. Newly developed analytical technologies allow better characterization MPs, but characterizing nanosized plastic particles remains challenging. Transport debris land to oceans is key driver for marine pollution, and relative contributions riverine runoff atmospheric deposition must be further quantified. Another lingering issue whether can bioaccumulate biomagnify along food web, which demands investigations. Currently there no health risk assessment human exposure probably due lack reference threshold values. Hence, establishing values should long-term continuing task scientific community. Recent progress quantifying vertical settling deep brightened prospect finding "Missing Plastics", at least partially. Future efforts are urgently needed developing novel techniques, conducting additional laboratory field measurements, formulating robust models understand occurrence, fate, effects on planet.

Язык: Английский

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Microplastic co-exposure elevates cadmium accumulation in mouse tissue after rice consumption: Mechanisms and health implications

Journal of Hazardous Materials, Год журнала: 2024, Номер 476, С. 135218 - 135218

Опубликована: Июль 17, 2024

Язык: Английский

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