Biocatalytic Hydrogenation of Biomass-Derived Furan Aldehydes to Alcohols
Journal of Agricultural and Food Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 14, 2025
The
biomass-derived
furan
aldehydes
furfural
(FF)
and
5-hydroxymethylfurfural
(HMF)
are
versatile
platform
chemicals
used
to
produce
various
value-added
through
further
valorization
processes.
Selectively
reducing
C═O
in
FF
HMF
molecules
form
furfuryl
alcohol
(FAL)
2,5-bis(hydroxymethyl)furan
(BHMF),
represents
an
important
research
field
upgrading
biomass-based
compounds.
Currently,
the
reduction
of
alcohols
chemical
transformation
often
leads
unavoidable
environmental
issues
formation
potential
byproducts.
Biocatalysis
has
demonstrated
expanded
applications
converting
into
a
diverse
array
chemicals.
This
process
exhibits
significant
organic
synthesis
biotechnology
due
its
green
sustainable
properties.
biocatalytic
especially
route
for
selective
FAL
BHMF.
review
discusses
recent
progress
biosynthesis
BHMF
from
Recently
discovered
enzymes
whole
cells
as
biocatalysts
production
summarized.
In
addition,
chemoenzymatic
cascades
synthesizing
biomass
hydrolysate
raw
materials
also
discussed.
Язык: Английский
Integrating Enzymes with Supramolecular Polymers for Recyclable Photobiocatalytic Catalysis
Angewandte Chemie International Edition,
Год журнала:
2024,
Номер
63(16)
Опубликована: Фев. 22, 2024
Chemical
modifications
of
enzymes
excel
in
the
realm
enzyme
engineering
due
to
its
directness,
robustness,
and
efficiency;
however,
challenges
persist
devising
versatile
effective
strategies.
In
this
study,
we
introduce
a
supramolecular
modification
methodology
that
amalgamates
polymer
with
Candida
antarctica
lipase
B
(CalB)
create
(SupEnzyme).
This
approach
features
straightforward
preparation
amphiphilic
(β-CD@SMA),
which
was
subsequently
conjugated
enzyme,
resulting
SupEnzyme
capable
self-assembly
into
nanoparticles.
The
nanoparticles
can
form
micron-scale
aggregates
through
electrostatic
interactions
guest
entities,
thus
enhancing
catalyst
recycling.
Remarkably,
these
maintain
80
%
activity
after
seven
cycles,
outperforming
Novozym
435.
Additionally,
they
effectively
initiate
photobiocatalytic
cascade
reactions
using
photocatalysts.
As
consequence,
our
exhibits
noteworthy
adaptability
modification,
presenting
platform
for
various
polymer,
biocompatible
pairings,
potential
applications
fields
chemistry
biology.
Язык: Английский
Conceptual Process Design and Techno-Economic Analysis of Biocatalytic Furfural Hydrogenation Using Ethanol as the Terminal Reductant
ACS Sustainable Chemistry & Engineering,
Год журнала:
2024,
Номер
12(29), С. 10776 - 10785
Опубликована: Июль 9, 2024
Redox
enzyme-catalyzed
reactions
can
be
crucial
to
the
development
of
a
circular
bio-economy
by
facilitating
valorization
biomass-based
feedstock
materials,
such
as
bioethanol
and
furfural.
The
potential
yeast
alcohol
dehydrogenase-catalyzed
furfural
reduction
furfuryl
using
ethanol
terminal
reductant
has
been
well-documented
in
literature
free
immobilized
enzymes.
In
this
study,
systematic,
comprehensive
techno-economic
analysis
acetaldehyde
coproduction
is
presented.
A
conceptual
process
design
for
production
separation
products
developed,
economics
performed
study
challenges
technology.
Two
scenarios
derived
from
both
actual
experimental
data
hypothetical
assumptions
were
studied
understand
factors
behind
economic
feasibility.
It
was
observed
that
high
concentrations
organics
reactor
product
stream
low
cost
starting
raw
materials
are
most
feasibility
achieving
minimum
selling
prices
coproducts
could
comparable
current
market
prices.
results
form
basis
future
life
cycle
analyses.
Язык: Английский
Integrating Enzymes with Supramolecular Polymers for Recyclable Photobiocatalytic Catalysis
Angewandte Chemie,
Год журнала:
2024,
Номер
136(16)
Опубликована: Фев. 22, 2024
Abstract
Chemical
modifications
of
enzymes
excel
in
the
realm
enzyme
engineering
due
to
its
directness,
robustness,
and
efficiency;
however,
challenges
persist
devising
versatile
effective
strategies.
In
this
study,
we
introduce
a
supramolecular
modification
methodology
that
amalgamates
polymer
with
Candida
antarctica
lipase
B
(CalB)
create
(SupEnzyme).
This
approach
features
straightforward
preparation
amphiphilic
(β‐CD@SMA),
which
was
subsequently
conjugated
enzyme,
resulting
SupEnzyme
capable
self‐assembly
into
nanoparticles.
The
nanoparticles
can
form
micron‐scale
aggregates
through
electrostatic
interactions
guest
entities,
thus
enhancing
catalyst
recycling.
Remarkably,
these
maintain
80
%
activity
after
seven
cycles,
outperforming
Novozym
435.
Additionally,
they
effectively
initiate
photobiocatalytic
cascade
reactions
using
photocatalysts.
As
consequence,
our
exhibits
noteworthy
adaptability
modification,
presenting
platform
for
various
polymer,
biocompatible
pairings,
potential
applications
fields
chemistry
biology.
Язык: Английский
Polymer-Based Strategies for Enzyme Immobilization: A Comprehensive Review
Tuijin Jishu/Journal of Propulsion Technology,
Год журнала:
2023,
Номер
44(5), С. 792 - 802
Опубликована: Дек. 1, 2023
Enzyme
immobilization
refers
to
the
process
of
attaching
or
confining
enzymes
onto
a
solid
support
within
matrix,
often
made
polymers
other
materials.
This
creates
stable
and
controlled
environment
for
enzyme
interact
with
substrates
perform
catalysis.
The
primary
goal
is
enhance
stability,
reusability,
activity
under
specific
conditions,
making
them
more
practical
efficient
various
biotechnological,
industrial,
medical
applications.
Immobilization
methods
can
vary
widely,
including
physical
adsorption,
covalent
bonding,
entrapment
matrices,
encapsulation,
crosslinking,
more.
These
provide
means
control
interactions
between
surrounding
environment,
affecting
factors
such
as
substrate
accessibility,
orientation,
stability.
Due
their
ease
fabrication
superior
structural
adaptability,
polymer
compounds
in
variety
forms,
beads,
films,
fibers,and
coatings,have
become
popular
supportive
materials
immobilization.
For
immobilization,
number
natural
polymers,
agar,
agarose,
alginate,
dextran,
chitosan,and
carrageenan,
well
synthetic
polyamides,
polystyrene,
polyacrylamide,
are
employed
carrier
system.
offers
cost-effective
system
applications
biotechnology,
industry,
research.
Язык: Английский