Beverage Plant Research,
Год журнала:
2023,
Номер
3(1), С. 0 - 0
Опубликована: Янв. 1, 2023
Jinhua
Xiangyuan
(JHXY)
is
a
unique
type
of
Chinese
tea
made
from
roasted
oolong
and
subsequently
fermented
by
Eurotiumcristatum.
In
this
study,
we
investigated
the
potential
benefits
JHXY
on
obese
rats
induced
high-sucrose
high-fat
diet.
infusion
was
administered
orally
at
1.6
g/kg·bw
(HI),
0.8
(MI),
0.4
(LI)
per
day
for10
weeks.
Weight
gain
significantly
suppressed
without
affecting
appetite.
MI
HI
groups,
led
to
significant
reduction
in
triglycerides
(TG),
total
cholesterol
(TC),
low-density
lipoprotein
(LDL-C),
accompanied
an
increase
high-density
(HDL-C)
levels.
A
white
adipose
tissue
(WAT)
index
brown
(BAT)
were
observed.
group,
morphology
hepatocytes
restored.
The
abundance
Bifidobacterium
elevated,
whereas
Desulfovibrio
reduced.
Correlation
analysis
revealed
that
ratio
Ruminococcus
positively
correlated
with
HDL-C;
Christensenellaceae_R7_group
negatively
TC
LDL-C,
while
Lactobacillus
BAT/WAT
ratio.
lipopolysaccharide
biosynthesis
pathway
predicted
be
weakened
(p<0.05);
sulfur
relay
system
attenuated,
bacterial
toxins
augmented
(p<0.05).
Our
research
showed
has
enhance
metabolic
health
maintain
intestinal
homeostasis.
Optimal
dosage
should
focal
point
future
research.
Journal of Agricultural and Food Chemistry,
Год журнала:
2023,
Номер
71(36), С. 13363 - 13375
Опубликована: Авг. 30, 2023
The
objective
of
the
current
study
was
to
explore
potential
mechanism
Ziyang
selenium-enriched
green
tea
polysaccharide
(Se-GTP)
against
obesity.
results
showed
that
Se-GTP
significantly
alleviated
obesity
and
related
metabolic
disorders
caused
by
high-fat
diet
(HFD)
in
mice.
16S
rRNA
gene
sequencing
revealed
improved
gut
microbiota
disturbance
obese
mice
facilitated
proliferation
probiotics
such
as
Bacteroides,
Bifidobacterium,
Lactobacillus,
Akkermansia.
In
addition,
colonic
content
succinate,
a
product
microbial
metabolite
connection
with
adipocyte
thermogenesis,
enhanced
treatment.
Therefore,
brown
adipose
tissue
(BAT)
thermogenesis
inguinal
white
(iWAT)
browning
mice,
which
could
be
increased
expressions
thermogenic
marker
proteins
UCP1,
PGC-1α,
CIDEA
BAT
iWAT.
Interestingly,
intervention
also
observably
M2-like
macrophages
iWAT
To
summarize,
this
are
first
show
can
stimulate
counteract
obesity,
may
pertinent
alteration
Journal of Agricultural and Food Chemistry,
Год журнала:
2024,
Номер
72(13), С. 7230 - 7243
Опубликована: Март 18, 2024
Long-term
high-fat
diet
(HFD)
will
induce
dysbiosis
and
a
disturbance
of
intestinal
homeostasis.
Large
yellow
tea
polysaccharide
(LYP)
has
been
shown
to
improve
obesity-associated
metabolic
disease
via
modulation
the
M2
polarization.
However,
contribution
LYP
barrier
impairment
improvement
mechanisms
in
obesity
caused
by
an
HFD
are
still
not
clear.
In
this
study,
we
evaluated
impacts
on
mucosal
function
microbiota
composition
HFD-feeding
mice.
Results
exhibited
that
dietary
supplement
could
ameliorate
physical
maintaining
integrity
elevating
tight-junction
protein
production,
strengthen
chemical
up-regulating
levels
glucagon-like
peptide-1
increasing
mucin-producing
goblet
cell
numbers,
enhance
immune
though
suppressing
subsets
cytokines
toward
pro-inflammatory
phenotypes.
Moreover,
reshaped
constitution
metabolism
flora
enriching
probiotics
produce
short-chain
fatty
acids.
Overall,
might
be
used
as
critical
regulator
homeostasis
host
health
promoting
gut
integrity,
modulating
response,
inhibiting
bowel
inflammation.
Frontiers in Nutrition,
Год журнала:
2024,
Номер
10
Опубликована: Янв. 17, 2024
Traditional
Chinese
medicine
(TCM)
has
displayed
preventive
and
therapeutic
effects
on
many
complex
diseases.
As
natural
biological
macromolecules,
TCM-derived
antiobesogenic
polysaccharides
(TCMPOs)
exhibit
notable
weight-loss
are
seen
to
be
a
viable
tactic
in
the
fight
against
obesity.
Current
studies
demonstrate
that
antiobesity
activity
of
TCMPOs
is
closely
related
their
structural
characteristics,
which
could
affected
by
extraction
purification
methods.
Therefore,
extraction,
structural-property
correlations
were
discussed.
Investigation
mechanism
also
essential
for
improved
application.
Herein,
possible
mechanisms
systematically
summarized:
(1)
modulation
appetite
satiety
effects,
(2)
suppression
fat
absorption
synthesis,
(3)
alteration
gut
microbiota
metabolites,
(4)
protection
intestinal
barriers.
This
collated
information
provide
some
insights
offer
new
approach
management
prevention
Journal of Functional Foods,
Год журнала:
2023,
Номер
102, С. 105468 - 105468
Опубликована: Фев. 24, 2023
Tea
has
been
used
medicinally
and
dietarily
for
thousands
of
years.
polysaccharides
(TPS),
considered
one
the
main
bioactive
components
tea,
show
diverse
health
benefits.
Yet
it
received
far
less
attention
than
tea
polyphenols.
During
recent
decades,
considerable
researches
have
dedicated
to
TPS,
including
extraction,
structural
characteristics,
potential
bioactivity.
Recent
studies
suggested
that
biological
effects
dietary
TPS
are
subjected
gut
microbiota
(GM)
modulation.
Thus,
this
review
focuses
on
research
advance
structure
characteristics
degradation
in
gut,
modulation
diversity
GM
production
short
chain
fatty
acids
(SCFAs),
benefits
through
targeting
GM.
Furthermore,
some
future
directions
were
also
proposed.
The
purpose
is
enhance
our
understanding
health-promoting
properties
promote
further
TPS.
Food & Function,
Год журнала:
2023,
Номер
14(24), С. 10910 - 10923
Опубликована: Янв. 1, 2023
The
antidiabetic
effects
and
underlying
mechanisms
of
the
polysaccharides
extracted
from
Fu
brick
tea
(FBTP)
were
investigated
in
high-fat
diet/streptozotocin-induced
type
2
diabetes
mellitus
(T2DM)
rats.
