In
this
study,
we
investigated
how
different
proportions
blends
of
RG-I
pectic
polysaccharides
and
hesperidin
impact
the
gut
microbiota
metabolites
using
an
in
vitro
simulated
digestion
fermentation
model.
The
results
indicated
that
both
them
could
modulate
produce
beneficial
metabolites.
However,
their
particular
exhibited
remarkable
synergistic
effects
on
modulating
intestinal
microenvironment,
surpassing
observed
with
individual
components.
Specifically,
these
enhance
acidogenic
potential,
increase
short-chain
fatty
acids
production,
improve
bioavailability,
promote
microbial
diversity.
This
additive
effect
was
inseparable
from
role
microbiota.
Certain
bacteria,
such
as
Blautia,
Faecalibacterium,
Prevotella,
strong
preferences
for
those
blends,
thereby
contributing
to
host
health
through
participating
carbohydrate
flavonoid
metabolism.
Comprehensive Reviews in Food Science and Food Safety,
Год журнала:
2023,
Номер
22(6), С. 4831 - 4870
Опубликована: Сен. 26, 2023
Abstract
Polysaccharides
are
promising
biomolecules
with
lowtoxicity
and
diverse
bioactivities
in
food
processing
clinical
drug
development.
However,
an
essential
prerequisite
for
their
applications
is
the
fine
structure
characterization.
Due
to
complexity
of
polysaccharide
structure,
partial
degradation
a
powerful
tool
analysis,
which
can
effectively
provide
valid
information
on
backbone
branching
glycosidic
fragments
complex
polysaccharides.
This
review
aims
conclude
current
methods
employed
structural
characterization,
discuss
molecular
mechanisms,
describe
solution
properties
degraded
In
addition,
effects
conformational
relationships
between
bioactivities,
such
as
antioxidant,
antitumor,
immunomodulatory
activities,
also
discussed.
Finally,
we
summarize
prospects
challenges
will
be
great
value
scientific
elucidation
structures
potential
applications.
Critical Reviews in Food Science and Nutrition,
Год журнала:
2023,
Номер
64(33), С. 12242 - 12271
Опубликована: Авг. 31, 2023
Natural
products
of
plant
origin
are
high
interest
and
widely
used,
especially
in
the
food
industry,
due
to
their
low
toxicity
wide
range
bioactive
properties.
Compared
other
components,
safety
polysaccharides
has
been
generally
recognized.
As
dietary
fibers,
plant-derived
mostly
degraded
intestine
by
polysaccharide-degrading
enzymes
secreted
gut
microbiota,
have
potential
prebiotic
activity
both
non-disease
disease
states,
which
should
not
be
overlooked,
terms
involvement
treatment
intestinal
diseases
promotion
health.
This
review
elucidates
regulatory
effects
on
microbiota
summarizes
mechanisms
involved
targeting
for
diseases.
Further,
structure-activity
relationships
between
different
structural
types
occurrence
further
explored.
Finally,
practical
applications
production
packaging
summarized
discussed,
providing
important
references
expanding
application
industry
or
developing
functional
supplements.
Ultrasonics Sonochemistry,
Год журнала:
2024,
Номер
106, С. 106895 - 106895
Опубликована: Май 1, 2024
Tartary
buckwheat
(Fagopyrum
tataricum
(L.)
Gaertn)
leaf
has
abundant
rhamnogalacturonan-I
enriched
pectic
polysaccharides,
which
exert
various
health-promoting
effects.
Nevertheless,
the
potential
relationship
between
chemical
structure
and
biological
function
of
polysaccharides
from
leaves
(TBP)
remains
unclear.
Therefore,
to
bridge
gap
TBP,
impacts
ultrasound-assisted
Fenton
degradation
(UFD)
mild
alkaline
de-esterification
(MAD)
on
structural
properties
effects
TBP
were
systematically
studied.
Compared
with
native
(molecular
mass,
9.537
×
104
Da),
molecular
masses
degraded
TBPs
(TBP-MMW,
4.811
Da;
TBP-LMW,
2.101
Da)
significantly
reduced
by
UFD
modification,
while
their
primary
structures
overall
stable.
Besides,
compared
(esterification
degree,
22.73
%),
esterification
degrees
de-esterified
(TBP-MDE,
14.27
%;
TBP-LDE,
6.59
%)
notably
MAD
also
Furthermore,
results
revealed
that
both
modifications
could
improve
antioxidant,
antiglycation,
immunostimulatory
TBP.
Indeed,
TBP's
negatively
correlated
its
mass
positively
linked
free
uronic
acids.
The
findings
demonstrate
are
promising
techniques
for
modification
can
remarkedly
promote
present
conducive
better
understanding
structure-bioactivity
relationship.
