Rg-I Pectic Polysaccharides and Hesperidin Synergistically Modulate Gut Microbiota: An in Vitro Study Targeting the Proportional Relationship DOI
Jiaxiong Wu,

Sihuan Shen,

Huan Cheng

и другие.

Опубликована: Янв. 1, 2024

In this study, we investigated how different proportions blends of RG-I pectic polysaccharides and hesperidin impact the gut microbiota metabolites using an in vitro simulated digestion fermentation model. The results indicated that both them could modulate produce beneficial metabolites. However, their particular exhibited remarkable synergistic effects on modulating intestinal microenvironment, surpassing observed with individual components. Specifically, these enhance acidogenic potential, increase short-chain fatty acids production, improve bioavailability, promote microbial diversity. This additive effect was inseparable from role microbiota. Certain bacteria, such as Blautia, Faecalibacterium, Prevotella, strong preferences for those blends, thereby contributing to host health through participating carbohydrate flavonoid metabolism.

Язык: Английский

Exploring the partial degradation of polysaccharides: Structure, mechanism, bioactivities, and perspectives DOI

Shi‐Kang Chen,

Xin Wang, Yuqing Guo

и другие.

Comprehensive Reviews in Food Science and Food Safety, Год журнала: 2023, Номер 22(6), С. 4831 - 4870

Опубликована: Сен. 26, 2023

Abstract Polysaccharides are promising biomolecules with lowtoxicity and diverse bioactivities in food processing clinical drug development. However, an essential prerequisite for their applications is the fine structure characterization. Due to complexity of polysaccharide structure, partial degradation a powerful tool analysis, which can effectively provide valid information on backbone branching glycosidic fragments complex polysaccharides. This review aims conclude current methods employed structural characterization, discuss molecular mechanisms, describe solution properties degraded In addition, effects conformational relationships between bioactivities, such as antioxidant, antitumor, immunomodulatory activities, also discussed. Finally, we summarize prospects challenges will be great value scientific elucidation structures potential applications.

Язык: Английский

Процитировано

66

Recent progress in plant-derived polysaccharides with prebiotic potential for intestinal health by targeting gut microbiota: a review DOI
Xiaozhen Wang, Xia Li, Luyao Zhang

и другие.

Critical Reviews in Food Science and Nutrition, Год журнала: 2023, Номер 64(33), С. 12242 - 12271

Опубликована: Авг. 31, 2023

Natural products of plant origin are high interest and widely used, especially in the food industry, due to their low toxicity wide range bioactive properties. Compared other components, safety polysaccharides has been generally recognized. As dietary fibers, plant-derived mostly degraded intestine by polysaccharide-degrading enzymes secreted gut microbiota, have potential prebiotic activity both non-disease disease states, which should not be overlooked, terms involvement treatment intestinal diseases promotion health. This review elucidates regulatory effects on microbiota summarizes mechanisms involved targeting for diseases. Further, structure-activity relationships between different structural types occurrence further explored. Finally, practical applications production packaging summarized discussed, providing important references expanding application industry or developing functional supplements.

Язык: Английский

Процитировано

35

A review on the hypoglycemic effect, mechanism and application development of natural dietary polysaccharides DOI
Yuhao Dong, Zhenxing Wang, Chunying Chen

и другие.

International Journal of Biological Macromolecules, Год журнала: 2023, Номер 253, С. 127267 - 127267

Опубликована: Окт. 28, 2023

Язык: Английский

Процитировано

31

Effect of in vitro digestion and fermentation of kiwifruit pomace polysaccharides on structural characteristics and human gut microbiota DOI Creative Commons

Mengyin Chen,

Xuefeng Chen, Yuxi Guo

и другие.

International Journal of Biological Macromolecules, Год журнала: 2023, Номер 253, С. 127141 - 127141

Опубликована: Сен. 28, 2023

Язык: Английский

Процитировано

26

Characterization and prebiotic potential of polysaccharides from Rosa roxburghii Tratt pomace by ultrasound-assisted extraction DOI
Zhenghao Chen, Xiaohui Yuan, Tingting Tu

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 268, С. 131910 - 131910

Опубликована: Апрель 26, 2024

Язык: Английский

Процитировано

15

In vitro digestion and fecal fermentation of basidiospore-derived exopolysaccharides from Naematelia aurantialba DOI
Tao Sun, Xiaoning Liang, Xiaoyi Xu

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 261, С. 129756 - 129756

Опубликована: Янв. 28, 2024

Язык: Английский

Процитировано

13

Effects of complex polysaccharides by Ficus carica Linn. polysaccharide and peach gum on the development and metabolites of human gut microbiota DOI
Bing Xu, Tao Feng, Shiqing Song

и другие.

Food Hydrocolloids, Год журнала: 2024, Номер 154, С. 110061 - 110061

Опубликована: Апрель 7, 2024

Язык: Английский

Процитировано

10

Impact of pectin structural diversity on gut microbiota: A mechanistic exploration through in vitro fermentation DOI
Wei-Hao Zhang,

Han-Yan Luo,

Wing-Shan Keung

и другие.

Carbohydrate Polymers, Год журнала: 2025, Номер 355, С. 123367 - 123367

Опубликована: Фев. 10, 2025

Язык: Английский

Процитировано

2

Effects of molecular weight on simulated digestion and fecal fermentation of polysaccharides from longan pulp in vitro DOI

Chunmei Xia,

Xiang Xu,

Ruifen Zhang

и другие.

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 141711 - 141711

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

2

Impacts of ultrasound-assisted Fenton degradation and alkaline de-esterification on structural properties and biological effects of pectic polysaccharides from Tartary buckwheat leaves DOI Creative Commons
Wenbing Li,

Jing Lei,

Mei-Mei Qu Mo

и другие.

Ultrasonics Sonochemistry, Год журнала: 2024, Номер 106, С. 106895 - 106895

Опубликована: Май 1, 2024

Tartary buckwheat (Fagopyrum tataricum (L.) Gaertn) leaf has abundant rhamnogalacturonan-I enriched pectic polysaccharides, which exert various health-promoting effects. Nevertheless, the potential relationship between chemical structure and biological function of polysaccharides from leaves (TBP) remains unclear. Therefore, to bridge gap TBP, impacts ultrasound-assisted Fenton degradation (UFD) mild alkaline de-esterification (MAD) on structural properties effects TBP were systematically studied. Compared with native (molecular mass, 9.537 × 104 Da), molecular masses degraded TBPs (TBP-MMW, 4.811 Da; TBP-LMW, 2.101 Da) significantly reduced by UFD modification, while their primary structures overall stable. Besides, compared (esterification degree, 22.73 %), esterification degrees de-esterified (TBP-MDE, 14.27 %; TBP-LDE, 6.59 %) notably MAD also Furthermore, results revealed that both modifications could improve antioxidant, antiglycation, immunostimulatory TBP. Indeed, TBP's negatively correlated its mass positively linked free uronic acids. The findings demonstrate are promising techniques for modification can remarkedly promote present conducive better understanding structure-bioactivity relationship.

Язык: Английский

Процитировано

7