Exploring the partial degradation of polysaccharides: Structure, mechanism, bioactivities, and perspectives

Comprehensive Reviews in Food Science and Food Safety, Journal Year: 2023, Volume and Issue: 22(6), P. 4831 - 4870

Published: Sept. 26, 2023

Abstract Polysaccharides are promising biomolecules with lowtoxicity and diverse bioactivities in food processing clinical drug development. However, an essential prerequisite for their applications is the fine structure characterization. Due to complexity of polysaccharide structure, partial degradation a powerful tool analysis, which can effectively provide valid information on backbone branching glycosidic fragments complex polysaccharides. This review aims conclude current methods employed structural characterization, discuss molecular mechanisms, describe solution properties degraded In addition, effects conformational relationships between bioactivities, such as antioxidant, antitumor, immunomodulatory activities, also discussed. Finally, we summarize prospects challenges will be great value scientific elucidation structures potential applications.

Language: Английский

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Impact of pectin structural diversity on gut microbiota: A mechanistic exploration through in vitro fermentation

Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: 355, P. 123367 - 123367

Published: Feb. 10, 2025

Language: Английский

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Effects of molecular weight on simulated digestion and fecal fermentation of polysaccharides from longan pulp in vitro

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141711 - 141711

Published: March 1, 2025

Language: Английский

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Recent progress in plant-derived polysaccharides with prebiotic potential for intestinal health by targeting gut microbiota: a review

Critical Reviews in Food Science and Nutrition, Journal Year: 2023, Volume and Issue: 64(33), P. 12242 - 12271

Published: Aug. 31, 2023

Natural products of plant origin are high interest and widely used, especially in the food industry, due to their low toxicity wide range bioactive properties. Compared other components, safety polysaccharides has been generally recognized. As dietary fibers, plant-derived mostly degraded intestine by polysaccharide-degrading enzymes secreted gut microbiota, have potential prebiotic activity both non-disease disease states, which should not be overlooked, terms involvement treatment intestinal diseases promotion health. This review elucidates regulatory effects on microbiota summarizes mechanisms involved targeting for diseases. Further, structure-activity relationships between different structural types occurrence further explored. Finally, practical applications production packaging summarized discussed, providing important references expanding application industry or developing functional supplements.

Language: Английский

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A review on the hypoglycemic effect, mechanism and application development of natural dietary polysaccharides

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 253, P. 127267 - 127267

Published: Oct. 28, 2023

Language: Английский

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Effect of in vitro digestion and fermentation of kiwifruit pomace polysaccharides on structural characteristics and human gut microbiota

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 253, P. 127141 - 127141

Published: Sept. 28, 2023

Language: Английский

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Characterization and prebiotic potential of polysaccharides from Rosa roxburghii Tratt pomace by ultrasound-assisted extraction

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 268, P. 131910 - 131910

Published: April 26, 2024

Language: Английский

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In vitro digestion and fecal fermentation of basidiospore-derived exopolysaccharides from Naematelia aurantialba

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 261, P. 129756 - 129756

Published: Jan. 28, 2024

Language: Английский

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Effects of complex polysaccharides by Ficus carica Linn. polysaccharide and peach gum on the development and metabolites of human gut microbiota

Food Hydrocolloids, Journal Year: 2024, Volume and Issue: 154, P. 110061 - 110061

Published: April 7, 2024

Language: Английский

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Impacts of ultrasound-assisted Fenton degradation and alkaline de-esterification on structural properties and biological effects of pectic polysaccharides from Tartary buckwheat leaves

Ultrasonics Sonochemistry, Journal Year: 2024, Volume and Issue: 106, P. 106895 - 106895

Published: May 1, 2024

Tartary buckwheat (Fagopyrum tataricum (L.) Gaertn) leaf has abundant rhamnogalacturonan-I enriched pectic polysaccharides, which exert various health-promoting effects. Nevertheless, the potential relationship between chemical structure and biological function of polysaccharides from leaves (TBP) remains unclear. Therefore, to bridge gap TBP, impacts ultrasound-assisted Fenton degradation (UFD) mild alkaline de-esterification (MAD) on structural properties effects TBP were systematically studied. Compared with native (molecular mass, 9.537 × 104 Da), molecular masses degraded TBPs (TBP-MMW, 4.811 Da; TBP-LMW, 2.101 Da) significantly reduced by UFD modification, while their primary structures overall stable. Besides, compared (esterification degree, 22.73 %), esterification degrees de-esterified (TBP-MDE, 14.27 %; TBP-LDE, 6.59 %) notably MAD also Furthermore, results revealed that both modifications could improve antioxidant, antiglycation, immunostimulatory TBP. Indeed, TBP's negatively correlated its mass positively linked free uronic acids. The findings demonstrate are promising techniques for modification can remarkedly promote present conducive better understanding structure-bioactivity relationship.

Language: Английский

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