Base‐Catalyzed [4+2] Annulation of Ynones and Acetates for the Synthesis of 2‐Pyrones DOI
Ting Chen,

Mao-Chun Ye,

Ting Huang

и другие.

Asian Journal of Organic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Окт. 30, 2024

Abstract An efficient, practical, and scalable Cs 2 CO 3 ‐catalyzed [4+2] annulation reaction between ynones acetates is presented, wherein serve as the four‐atom partners. This methodology facilitates synthesis of substituted 2‐pyrones with yields ranging from good to excellent. The ready availability starting materials, coupled simplicity protocol, renders this approach highly amenable preparation a diverse range 2‐pyrones. Furthermore, feasibility on gram scale its application in potent selective cyclooxygenase‐2 inhibitor underscore practical significance utility method.

Язык: Английский

Metal-Free Catalysis in C–C Single-Bond Cleavage: Achievements and Prospects DOI
Mohit L. Deb,

B. Shriya Saikia,

Iftakur Rahman

и другие.

Topics in Current Chemistry, Год журнала: 2022, Номер 380(5)

Опубликована: Авг. 11, 2022

Язык: Английский

Процитировано

7

Progress in Construction of 2H-Pyrrol-2-ones Skeleton DOI
Donghan Liu,

Xihang Lu,

Zhangmengjie Chai

и другие.

Chinese Journal of Organic Chemistry, Год журнала: 2023, Номер 43(1), С. 57 - 57

Опубликована: Янв. 1, 2023

Язык: Английский

Процитировано

4

Synthesis of 2-(Cyanomethyl)benzoic Esters via Carbon–Carbon Bond Cleavage of Indanones DOI
Xiangtai Meng, Dengfeng Chen, Rui Liu

и другие.

The Journal of Organic Chemistry, Год журнала: 2021, Номер 86(15), С. 10852 - 10860

Опубликована: Июль 27, 2021

A novel synthesis of 2-(cyanomethyl)benzoic esters from indanone derivatives has been established. This reaction proceeds via a deprotonation alcohols with chemical base, followed by nucleophilic addition to indanones and Beckmann fragmentation. In addition, this could also work under electrochemical conditions, no external bases were needed. mild method offers strategy for the late-stage functionalization various natural alcohols.

Язык: Английский

Процитировано

3

CuCl2·2H2O/TBHP mediated synthesis of β-enaminones via coupling reaction of vinyl azides with aldehydes DOI
Yaohong Zhang,

Mengqiang Luo,

Yichan Zhang

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2022, Номер 20(9), С. 1952 - 1957

Опубликована: Янв. 1, 2022

A facile and efficient oxidative functionalization of vinyl azides with aldehydes furnishing a diverse array β-acylated enaminones was developed.

Язык: Английский

Процитировано

2

Base‐Catalyzed [4+2] Annulation of Ynones and Acetates for the Synthesis of 2‐Pyrones DOI
Ting Chen,

Mao-Chun Ye,

Ting Huang

и другие.

Asian Journal of Organic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Окт. 30, 2024

Abstract An efficient, practical, and scalable Cs 2 CO 3 ‐catalyzed [4+2] annulation reaction between ynones acetates is presented, wherein serve as the four‐atom partners. This methodology facilitates synthesis of substituted 2‐pyrones with yields ranging from good to excellent. The ready availability starting materials, coupled simplicity protocol, renders this approach highly amenable preparation a diverse range 2‐pyrones. Furthermore, feasibility on gram scale its application in potent selective cyclooxygenase‐2 inhibitor underscore practical significance utility method.

Язык: Английский

Процитировано

0