Visible-Light-Induced Cascade Radical Cyclization to Access Sulfamoylated Benzo[4,5]imidazo[2,1-a]isoquinolin-6(5H)-ones DOI
Rong Huang, Wenbo Wang, Kui Lu

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Дек. 3, 2024

A visible-light-induced cascade radical sulfamoylation/cyclization of 2-arylbenzoimidazoles to access sulfamoylated benzo[4,5]imidazo[2,1- a ]isoquinolin-6(5 H )-ones was achieved.

Язык: Английский

Construction of a Dual-Functionalized Acid–Base Nanocatalyst via HEPES Buffer Functionalized on Fe3O4 as a Reusable Catalyst for Annulation Reactions DOI

Maryam Borzooei,

Masoomeh Norouzi, Masoud Mohammadi

и другие.

Langmuir, Год журнала: 2024, Номер 40(26), С. 13397 - 13411

Опубликована: Июнь 20, 2024

Herein, we present a highly efficient dual-functionalized acid–base nanocatalyst, denoted as Fe3O4@GLYMO-HEPES, featuring sulfuric acid and tertiary amines its dual functional components. This catalyst is synthesized through the immobilization of 4-(2-hydroxyethyl)-1-piperazineethanesulfonic (HEPES) source these functionalities onto magnetite (Fe3O4) using 3-glycidoxypropyltriethoxysilane (GLYMO) linker. Characterization studies confirm integrity Fe3O4 core, with GLYMO-HEPES coating exhibiting no phase changes. Furthermore, Fe3O4@GLYMO-HEPES nanoparticles demonstrate uniform size distribution without aggregation. Notably, exhibits remarkable stability up to 200 °C possesses saturation magnetization value 31.5 emu/g, facilitating easy recovery via magnetic separation. These findings underscore potential versatile recyclable nanocatalyst for various applications. Its catalytic ability was evaluated in synthesis pyrano[2,3-c]pyrazoles 2-amino-3-cyano-4H-chromenes tandem Knorr–Knoevenagel–Michael–Thorpe–Ziegler-type heterocyclization mechanism, different aldehydes. A wide range fused heterocycles having good excellent yields. The process cost-effective, safe, sustainable, scalable, can be reused five times. prepared found stable heterogeneous showed recyclability.

Язык: Английский

Процитировано

19
Photocatalytic synthesis of dual acylmethylation derivates of indole[2,1-a]isoquinolinones via tandem cyclization/C3 acyl methylation DOI
Zongbo Xie, Wenli Li, Weiwei Zhang

и другие.

Molecular Catalysis, Год журнала: 2025, Номер 580, С. 115058 - 115058

Опубликована: Апрель 15, 2025

Язык: Английский

Процитировано

1
Photo-Driven Regiodivergent Arylation/Cyclization and Arylation/Hydroxylation of N-Aryl Methacrylamides with Aryltriazenes: Access to Functionalized 3,3-Disubstituted Oxindoles and α-Hydroxylamides DOI

Xinlei Zhou,

Wei Xu,

Bin Wang

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(18), С. 13345 - 13358

Опубликована: Авг. 21, 2024

A metal-free, light-induced regiodivergent functionalization of α,β-unsaturated amides with aryltriazenes under ambient conditions was developed. The visible light and B(C

Язык: Английский

Процитировано

3
Pentafluorosulfanylation of Acrylamides: The Synthesis of SF5-Containing Isoquinolinediones with SF5Cl DOI
Xinqiang Tan,

Yuezhen Li,

Ziyou Hao

и другие.

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(21), С. 15941 - 15952

Опубликована: Окт. 24, 2024

We disclose herein an efficient and facile method for the synthesis of SF5-containing isoquinolinediones with all-carbon quaternary stereocenter via intramolecular pentafluorosulfanylation acrylamides using SF5Cl as a reagent. The protocol proceeds under mild reaction conditions enjoys broad substrate scope, wide functional group compatibility, high atom- step-economy. A radical mechanism involving SF5 cascade addition/cyclization is proposed.

Язык: Английский

Процитировано

3
Visible-light-mediated selenocyclization of o-vinylanilides with diselenides DOI

X.Y. Wang,

Jingwei Guo,

Shaofan Xue

и другие.

Organic & Biomolecular Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

A visible-light-induced selenocyclization of o -vinylanilides with diselenides using molecular oxygen as a terminal oxidant has been developed.

Язык: Английский

Процитировано

0
Recent developments for the synthesis of the dihydroisoquinolin-1(2H)-ones via cyclization of N-allylbenzamides DOI
Yan‐Ning Niu, Keyu Wang, Fuzhong Han

и другие.

Tetrahedron, Год журнала: 2025, Номер unknown, С. 134497 - 134497

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
Photoinduced Cascade Synthesis of Oxindoles and Isoquinolinediones DOI

Avishek Kumar Jha,

Gayathri K. L,

Veera Reddy Yatham

и другие.

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Март 19, 2025

Herein, we developed alkyl radical generation from C(sp3)–H bonds of alkanes via a photoinduced HAT-process without employing an external metal, photocatalyst, and organic peroxide. The generated participates in addition cascade cyclization N-arylacrylamides/N-acryloyl benzamides to deliver structurally diverse valuable functionalized oxindoles isoquinolinediones moderate good yields. Preliminary mechanistic studies indicated the aryl through homolytic cleavage Ar–I direct photoexcitation iodide.

Язык: Английский

Процитировано

0
Bifunctional Ionic Liquids Induced Electrochemical C–H Arylation of Quinoxalin(on)es with Aryltriazenes DOI
Chen‐Yu Li,

Wei Xu,

Bin Wang

и другие.

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Май 15, 2025

An efficient bifunctional ionic-liquid-induced electrochemical C-H arylation of quinoxalin(on)es with aryltriazenes has been developed. The reaction utilizes as stable reagents and ionic liquids promoter electrolyte. Various arylated quinoxalin-2(1H)-ones, quinoxaline 2-methyldibenzo[f,h]quinoxaline were assembled in modest to excellent yields under mild, metal- oxidant-free conditions. developed protocol features simple operation, good functional group tolerance, selectivity, product derivatization, practical gram-scale synthesis batch continuous-flow processes.

Язык: Английский

Процитировано

0
Visible Light-Induced Radical-Cascade Difluoroalkylation/Cyclization of Unsaturated Aldehyde Hydrazones for the Synthesis of Difluoroalkylated Dihydropyrazoles and Tetrahydropyridazines DOI
Hui Chen,

Kaifa Zhang,

Kun Xia

и другие.

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Июнь 5, 2025

Visible light-induced radical 5/6-endo-trig difluoroalkylation/cyclization of N-allyl and homoallyl aldehyde hydrazones with various fluoroalkyl bromides has been achieved. The reaction was carried out alkyl difluoroacetates difluoroacetamide as difluoroalkylation reagents Eosin Y an organic photocatalyst. Various difluoroalkylated dihydropyrazoles tetrahydropyridazines were obtained under metal-free mild conditions.

Язык: Английский

Процитировано

0
Lewis Acidic Ionic-Liquid-Catalyzed Radical-Cascade Alkylation/Cyclization of N-Alkyl-N-methacryloyl Benzamides with Alkanes via Visible-Light-Induced Ligand-to-Metal Charge Transfer: Access to Alkylated Isoquinoline-1,3(2H,4H)-diones DOI
Tao Zhang, Xinxin Ren, Jingkun Li

и другие.

Organic Letters, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 21, 2024

With the flourishing progress of ligand-to-metal charge transfer (LMCT) photocatalysis, various metals were developed as catalysts to activate abundant alkane feedstocks for synthesis functionalized organic compounds. However, best our knowledge, most LMCT are difficult recover and reuse next cycles. Herein, we report a reusable Lewis acidic ionic liquid (LAIL)-catalyzed radical-cascade alkylation/cyclization N-alkyl-N-methacryloyl benzamides with unactivated alkanes alkylated isoquinoline-1,3-(2H,4H)-diketones. The protocol features mild reaction conditions, high atom utilization efficiency, scale-up synthesis, simple operation, recycling catalysts.

Язык: Английский

Процитировано

2