Sustainable and scalable one-pot synthesis of diaryliodonium salts

Chemical Communications, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Two one-pot syntheses of diaryliodonium triflates are presented, rendering the production these electrophilic arylating agents more sustainable.

Язык: Английский

Transition-Metal-Free C-Diarylations to Reach All-Carbon Quaternary Centers

JACS Au, Год журнала: 2024, Номер 4(8), С. 2832 - 2837

Опубликована: Авг. 5, 2024

Herein, we disclose a convenient protocol for the α-diarylation of carbon nucleophiles to yield heavily functionalized quaternary products. Diaryliodonium salts are utilized transfer both aryl groups under transition-metal-free conditions, which enables an atom-efficient and high-yielding method with broad functional group tolerance. The methodology is amenable wide variety can be in late-stage functionalization complex arenes. Furthermore, it compatible new class zwitterionic iodonium reagents, gives access phenols

Язык: Английский

Synthesis of Diaryl Ethers via Hypervalent Iodine-Mediated C–H Functionalization

Organic Letters, Год журнала: 2024, Номер 26(37), С. 7864 - 7868

Опубликована: Сен. 9, 2024

A hypervalent iodine-reagent-based C-H functionalization strategy was utilized to synthesize diaryl ethers. This method directly transforms various arenes into their corresponding diaryliodonium salts, followed by a C-O coupling reaction produce structurally diverse The efficacy of this approach in the late-stage structural modifications complex molecules demonstrated.

Язык: Английский