Synthesis of Diaryl Ethers via Hypervalent Iodine-Mediated C–H Functionalization DOI

Chenghu Hu,

Qi Jia,

Wenjing Bao

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(37), P. 7864 - 7868

Published: Sept. 9, 2024

A hypervalent iodine-reagent-based C-H functionalization strategy was utilized to synthesize diaryl ethers. This method directly transforms various arenes into their corresponding diaryliodonium salts, followed by a C-O coupling reaction produce structurally diverse The efficacy of this approach in the late-stage structural modifications complex molecules demonstrated.

Language: Английский

Transition-Metal-Free C-Diarylations to Reach All-Carbon Quaternary Centers DOI Creative Commons
Shobhan Mondal,

Benjamin Gunschera,

Berit Olofsson

et al.

JACS Au, Journal Year: 2024, Volume and Issue: 4(8), P. 2832 - 2837

Published: Aug. 5, 2024

Herein, we disclose a convenient protocol for the α-diarylation of carbon nucleophiles to yield heavily functionalized quaternary products. Diaryliodonium salts are utilized transfer both aryl groups under transition-metal-free conditions, which enables an atom-efficient and high-yielding method with broad functional group tolerance. The methodology is amenable wide variety can be in late-stage functionalization complex arenes. Furthermore, it compatible new class zwitterionic iodonium reagents, gives access phenols

Language: Английский

Citations

4
Sustainable and scalable one-pot synthesis of diaryliodonium salts DOI Creative Commons
Sayad Doobary,

Leonard Kersting,

Piret Villo

et al.

Chemical Communications, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Two one-pot syntheses of diaryliodonium triflates are presented, rendering the production these electrophilic arylating agents more sustainable.

Language: Английский

Citations

0
Synthesis of Diaryl Ethers via Hypervalent Iodine-Mediated C–H Functionalization DOI

Chenghu Hu,

Qi Jia,

Wenjing Bao

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(37), P. 7864 - 7868

Published: Sept. 9, 2024

A hypervalent iodine-reagent-based C-H functionalization strategy was utilized to synthesize diaryl ethers. This method directly transforms various arenes into their corresponding diaryliodonium salts, followed by a C-O coupling reaction produce structurally diverse The efficacy of this approach in the late-stage structural modifications complex molecules demonstrated.

Language: Английский

Citations

1