Organic Chemistry Frontiers,
Год журнала:
2021,
Номер
9(3), С. 709 - 714
Опубликована: Дек. 10, 2021
Tunable
photoredox-catalyzed
chlorosulfonylation
and
oxysulfonylation
of
α-trifluoromethylstyrenes
with
sulfonyl
chloride
were
facilely
achieved
by
simply
manipulating
the
photocatalyst
solvent.
Chemical Society Reviews,
Год журнала:
2022,
Номер
51(6), С. 2313 - 2382
Опубликована: Янв. 1, 2022
Visible-light
photoredox
catalysis
has
been
regarded
as
an
extremely
powerful
tool
in
organic
chemistry,
bringing
the
spotlight
back
to
radical
processes.
The
versatility
of
photocatalyzed
reactions
already
demonstrated
be
effective
providing
alternative
routes
for
cross-coupling
well
multicomponent
reactions.
photocatalyst
allows
generation
high-energy
intermediates
through
light
irradiation
rather
than
using
highly
reactive
reagents
or
harsh
reaction
conditions.
In
a
similar
vein,
electrochemistry
experienced
fruitful
renaissance
generating
without
need
any
catalyst.
Such
milder
approaches
pose
basis
toward
higher
selectivity
and
broader
applicability.
electrochemical
reactions,
species
acts
starter
cascade
events.
This
diverse
reactivity
use
is
usually
not
covered
by
classical
methods.
Owing
availability
cheaper
more
standardized
photo-
reactors,
easily
scalable
flow-setups,
it
surprising
that
these
two
fields
have
become
areas
increased
research
interest.
Keeping
view,
this
review
aimed
at
overview
synthetic
design
MCRs
involving
and/or
activation
crucial
step
with
particular
focus
on
choice
difunctionalized
reagent.
Journal of the American Chemical Society,
Год журнала:
2021,
Номер
143(13), С. 4903 - 4909
Опубликована: Март 24, 2021
N-Heterocyclic
carbene
(NHC)
catalysis
has
emerged
as
a
versatile
tool
in
modern
synthetic
chemistry.
Further
increasing
the
complexity,
several
processes
have
been
introduced
that
proceed
via
dual
catalysis,
where
NHC
organocatalyst
operates
concert
with
second
catalytic
moiety,
significantly
enlarging
reaction
scope.
In
biological
transformations,
multiple
is
generally
used
to
access
complex
natural
products.
Guided
by
strategy,
triple
studied
recently,
three
different
modes
are
merged
single
process.
this
Communication,
direct
α-C–H
acylation
of
various
alkenes
aroyl
fluorides
using
NHC,
sulfinate,
and
photoredox
cooperative
reported.
The
method
allows
preparation
α-substituted
vinyl
ketones
moderate
high
yields
excellent
functional
group
tolerance.
Mechanistic
studies
reveal
these
cascades
through
sequential
radical
addition/coupling/elimination
contrast
known
operate
two
sets
interwoven
cycles,
process,
all
cycles
interwoven.
Organic & Biomolecular Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
This
review
highlights
the
recent
advances
in
multi-component
reactions
for
synthesizing
heterocyclic
compounds
via
green
approaches
including
photoredox
catalysis,
electrochemical
activation,
catalyst-free
methods
and
use
of
water
as
sole
solvent.
ChemistrySelect,
Год журнала:
2020,
Номер
5(42), С. 13103 - 13134
Опубликована: Ноя. 13, 2020
Abstract
Sodium
sulfinates,
sulfinic
acids,
sulfonyl
chlorides
and
hydrazides
as
readily
available
efficient
sulfonylation
reagents
have
been
extensively
explored
in
recent
years.
Sulfonyl
radical
can
be
generated
from
these
via
different
methods,
then
the
could
react
with
various
substrates
pathways
to
afford
corresponding
products.
In
this
review,
we
will
summarize
progress
reaction
using
sodium
three
terms
of
reagents,
classify
reactions
into
four
types:
1.
Sulfonylation
sulfinates.
2.
acid.
3.
chlorides.
4.
hydrazides.
Green Chemistry,
Год журнала:
2021,
Номер
23(15), С. 5467 - 5473
Опубликована: Янв. 1, 2021
We
report
an
efficient
visible-light-induced
iodosulfonyl
reaction
of
alkenes
in
water
using
EDA
complex
strategy
at
room
temperature.
The
addition
a
cationic
surfactant
allows
for
the
easy
formation
colored
complexes
water.
ACS Catalysis,
Год журнала:
2022,
Номер
12(6), С. 3279 - 3285
Опубликована: Фев. 25, 2022
A
visible
light-driven
photoredox-catalyzed
and
copper(II)-assisted
three-component
radical
addition/hydroxylation
reaction
of
alkenes,
sulfur
ylides,
water
is
reported.
This
process
shows
broad
substrate
scope
high
functional
group
tolerance,
with
respect
to
both
readily
available
ylides
providing
high-yielding
practical
access
valuable
γ-hydroxy
carbonyl
compounds.
Key
the
success
controlled
generation
α-carbonyl
carbon
radicals
from
via
sulfonium
salts
by
a
visible-light-driven
proton-coupled
electron
transfer
(PCET)
strategy
in
mixture
2,2,2-trifluoroethanol/CH2Cl2.
Addition
Cu(TFA)2·H2O
helps
accelerate
radical-cation
crossover
improve
efficiency.
Mechanistic
studies
suggest
that
hydroxy
moiety
products
stems
water.
study
also
builds
up
platform
for
further
investigation
into
synthetic
chemistry
ylides.
Organic Letters,
Год журнала:
2023,
Номер
25(7), С. 1161 - 1165
Опубликована: Фев. 9, 2023
The
visible-light-induced
photoredox
carbon
radical
formation
from
aqueous
sulfoxonium
ylides
has
been
demonstrated
for
the
first
time.
While
direct
reduction
of
by
H2O
efficiently
generates
corresponding
hydrocarbon
compounds,
use
additional
alkenes
as
acceptors
alters
chemical
reactivity
to
achieve
alkene
carboarylation
N-arylacrylamides.
Mechanistic
studies
reveal
two
different
reaction
pathways
involved
in
resulting
release
dimethyl
sulfone
and
form
DMSO.
Organic Letters,
Год журнала:
2024,
Номер
26(3), С. 636 - 641
Опубликована: Янв. 10, 2024
A
photochemical
halogen-bonding-assisted
synthesis
of
vinyl
sulfones
via
radical–radical
cross-coupling
bromines
and
sodium
sulfinates
is
developed.
This
methodology
offers
a
facile
efficient
approach
to
various
with
excellent
functional
group
tolerance
under
metal-,
photocatalyst-,
base-,
oxidant-free
conditions.
The
reaction
also
applicable
for
the
late-stage
functionalization
drug
molecules
hectogram
scale.
Moreover,
instead
sulfites
being
prepared,
these
reactions
could
be
conducted
using
sulfonyl
chlorides
in
one-pot
method.