Chemistry of Heterocyclic Compounds, Год журнала: 2023, Номер 59(4-5), С. 193 - 200
Опубликована: Май 1, 2023
Язык: Английский
Green Chemistry, Год журнала: 2022, Номер 24(8), С. 3250 - 3256
Опубликована: Янв. 1, 2022
A convenient, environmentally friendly, visible-light-driven and EDA complex-promoted direct hydroxysulfenylation of styrenes under photocatalyst- transition metal-free has been developed with O 2 as the oxygen source EtOH solvent.
Язык: Английский
Процитировано
49
Beilstein Journal of Organic Chemistry, Год журнала: 2025, Номер 21, С. 770 - 797
Опубликована: Апрель 16, 2025
In this review, we describe recent advances in electrochemical green methods for the synthesis of various organophosphorus compounds through formation phosphorus–carbon, phosphorus–nitrogen, phosphorus–oxygen, phosphorus–sulfur, and phosphorus–selenium bonds. The impact different electrodes is also discussed matter. Graphite, platinum, RVC, nickel have been used extensively compounds. made method a promising preparing structures. This review an introduction to encourage scientists use electrosynthesis as green, precise, low-cost prepare phosphorous
Язык: Английский
Процитировано
1
Frontiers in Chemistry, Год журнала: 2022, Номер 10
Опубликована: Ноя. 3, 2022
The activation of C–H bond, and its direct one-step functionalization, is one the key synthetic methodologies that provides access to a variety practically significant compounds. Particular attention focused on modifications obtained at final stages synthesis complicated molecules, which requires high tolerance presence existing functional groups. Phosphorus an indispensable element life, phosphorus chemistry now experiencing renaissance due new emerging applications in medicinal chemistry, materials (polymers, flame retardants, organic electronics, photonics), agricultural (herbicides, insecticides), catalysis (ligands) other important areas science technology. In this regard, search for new, more selective, low-waste routes become relevant. context, electrosynthesis has proven be eco-efficient convenient approach many respects, where reagents are replaced by electrodes, reactants applied potential determines their “oxidizing or reducing ability”. An electrochemical such processes being developed rapidly demonstrates some advantages over traditional classical methods C-H phosphorylation. main reasons success exclusion excess from reaction system: as oxidants, agents, sometimes metal and/or improvers, challenge isolation, increase wastes reduce yield frequent incompatibility with these Ideal conditions include electron reactant (regulated potential) by-products hydrogen hydrocarbon. review summarizes analyzes achievements preparation various derivatives carbon-phosphorus bonds, collects data redox properties most commonly used precursors. Electrochemically induced reactions both without catalyst metals, competitive oxidation precursors leads either bond generation phosphorus-centered radicals (radical cations) states will examined. focuses publications past 5 years.
Язык: Английский
Процитировано
29
Organic Letters, Год журнала: 2024, Номер 26(12), С. 2365 - 2370
Опубликована: Март 20, 2024
A green visible-light-promoted and electron donor–acceptor (EDA) complex-driven synthetic strategy for the construction of value-added naphtho[1′,2′:4,5]imidazo[1,2-a]pyridines from 2-arylimidazo[1,2-a]pyridines with Z-α-bromocinnamaldehydes has been accomplished under photocatalyst- transition-metal-free conditions. This efficient annulation approach provides a new straightforward pathway annulative π-extension imidazo[1,2-a]pyridine-based aromatics. Moreover, sustainable methodology exhibits simple operation, wide range substrates, benign conditions, good functional group compatibility.
Язык: Английский
Процитировано
7
The Chemical Record, Год журнала: 2020, Номер 20(12), С. 1530 - 1552
Опубликована: Окт. 5, 2020
Abstract Organophosphorus chemistry is a broad field with multi‐dimensional applications in research area of organic, biology, drug design and agrochemicals. Conventional methods have been adopted extensively to access phosphorylated compounds that rely on the use toxic, moisture sensitive phosphorylating agents occur presence oxidants, catalysts, as well high temperatures harsh conditions are required for complete transformations. However, recent progress has made phosphorylation reactions using electricity introduce green sustainable synthetic procedures. These can be performed at mild proceed excellent atom economy. Herein, we targeted electrochemical generation new bonds such C(sp 3 ) −P, 2 O−P, N−P, S−P Se−P. This review aimed offer an overview developments methodology easy organophosphorus electrochemistry.
Язык: Английский
Процитировано
47
Chemical Synthesis, Год журнала: 2021, Номер unknown
Опубликована: Янв. 1, 2021
Chemical Synthesis is an open access peer-reviewed journal publishing original research involving all areas of the chemical sciences. The aims to be premier resource seminal and insightful showcases for researchers in both academia industry, providing a platform inspiration future chemistry. intends serve as preeminent international chemistry has ambition among first choices chemists publication their discoveries.
Язык: Английский
Процитировано
34
Advanced Synthesis & Catalysis, Год журнала: 2023, Номер 365(6), С. 900 - 905
Опубликована: Фев. 20, 2023
Herein, we report the development of transition-metal-catalyst- and external-oxidant-free electrochemical cross-coupling hydrogen-evolution chemistry involving glycine amides diarylphosphine oxides. A broad range biologically active α-aminophosphonates was obtained in moderate to good yields a clean sustainable manner. Moreover, TBAB (tetrabutylammonium bromide) electrolyte recycled four times without obvious loss reaction activity. this protocol performed on gram scale under slightly modified electrolytic conditions or combination with continuous flow microreactor technology. Control experiments were used disclose possible free-radical mechanism. As service our authors readers, journal provides supporting information supplied by authors. Such materials are peer reviewed may be re-organized for online delivery, but not copy-edited typeset. Technical support issues arising from (other than missing files) should addressed Please note: The publisher is responsible content functionality any Any queries content) directed corresponding author article.
Язык: Английский
Процитировано
15
Green Synthesis and Catalysis, Год журнала: 2021, Номер 3(1), С. 59 - 68
Опубликована: Окт. 25, 2021
A novel protocol was developed for the construction of highly functionalized 2-(diarylphosphoryl)-1,2-dihydropyridine derivatives (DAPDHPs) from 3-formylchromones (1), heterocyclic ketene aminals (HKAs, 2), and phosphine oxides (R2P(O)H, 3) via a novel, one-pot cascade reaction. Optimization reaction conditions determined that refluxing mixture 3-formylchromones, HKAs, various R2P(O)H in propylene carbonate (PC) presence triethylamine as base facilitated highest yields DAPDHP products. This reaction, which involved cleavage one C–O bond 3-formylchromone substrates formation three new bonds (one C–C, C–N, C–P bond), enabled synthesis small library The dearomatized products were formed by regioselective nucleophilic addition reagents to intermediate pyridinium salts 8. approach has several advantages such use an environmentally-friendly solvent, simple practical operation (with filtration washing without column chromatography separation), good yields, product with potential biological activity.
Язык: Английский
Процитировано
29
Green Chemistry, Год журнала: 2023, Номер 25(11), С. 4528 - 4535
Опубликована: Янв. 1, 2023
A photocatalytic phosphorylation of heteroatom nucleophiles has been achieved via the direct coupling phosphorus-centered radical cations with nucleophiles.
Язык: Английский
Процитировано
11
The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(11), С. 7848 - 7858
Опубликована: Май 29, 2024
A CuH-catalyzed reductive coupling of nitroarenes with phosphine oxides is developed, which produces a series phosphamides in moderate to excellent yields good functional group tolerance. Gram-scale synthesis and late-stage modification nitro-aromatic molecule niclosamide are also successfully conducted. The mechanism study shows that the nitro transformed after being reduced nitroso nucleophilic addition procedure involved during reaction.
Язык: Английский
Процитировано
4