Recent Advances in Visible-Light Photoredox Catalysis for the Thiol-Ene/Yne Reactions

Molecules, Год журнала: 2022, Номер 27(3), С. 619 - 619

Опубликована: Янв. 18, 2022

Visible-light photoredox catalysis has been established as a popular and powerful tool for organic transformations owing to its inherent characterization of environmental friendliness sustainability in the past decades. The thiol-ene/yne reactions, direct hydrothiolation alkenes/alkynes with thiols, represents one most efficient atom-economic approaches carbon-sulfur bonds construction. In traditional methodologies, harsh conditions such stoichiometric reagents or specialized UV photo-apparatus were necessary suffering from various disadvantages. particular, visible-light also demonstrated be greener milder protocol reactions recent years. Additionally, unprecedented advancements have achieved this area during decade. review, we will summarize advances catalyzed 2015 2021. Synthetic strategies, substrate scope, proposed reaction pathways are mainly discussed.

Язык: Английский

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Photoinduced radical-polar crossover cyclization reactions

Chem Catalysis, Год журнала: 2024, Номер 4(5), С. 100945 - 100945

Опубликована: Март 5, 2024

Язык: Английский

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Photocatalytic Sulfonylation: Innovations and Applications

Chemistry - A European Journal, Год журнала: 2024, Номер unknown

Опубликована: Июль 14, 2024

Photosynthesis, converting sustainable solar energy into chemical energy, has emerged as a promising craft to achieve diverse organic transformations due its mild reaction conditions, sustainability, and high efficiency. The synthesis of sulfonated compounds drawn significant attention in the pharmaceuticals, agrochemicals, materials industries unique structure electronic properties sulfonyl groups. Over past decades, many photocatalytic sulfonylation reactions have been developed. In this review, recent advances photocatalyzed reviewed since 2020, with primary focus on discussing design mechanism.

Язык: Английский

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Metal-Catalyst-Free Radical Cyclization of 1,6-Enynes for the Selective and Switchable Synthesis of Lactams in Water

ACS Sustainable Chemistry & Engineering, Год журнала: 2022, Номер 10(18), С. 6057 - 6062

Опубликована: Апрель 27, 2022

Three types of novel radical cyclization 1,6-enynes with sulfonyl hydrazides have been presented, which provided convenient synthetic approaches for accessing five-membered cyclic lactams, lactams containing C–I bond, and six-membered lactams. Notably, these transformations are implemented in metal-catalyst-free systems, three classes important lactam derivatives were synthesized selectivity controllability from the same substrate using water as green solvent.

Язык: Английский

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Photoinduced cascade cyclization of alkynes with NH₄SCN: access to SCN-containing dibenzazepines or dioxodibenzothiazepines

Green Chemistry, Год журнала: 2022, Номер 24(12), С. 4742 - 4747

Опубликована: Янв. 1, 2022

Photoinduced tandem cyclization of alkynes with NH 4 SCN was developed for the synthesis various SCN-containing seven-membered N-heterocycles.

Язык: Английский

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Recent Advances in the Functionalization of Remote C−H Bonds by Hofmann‐Löffler‐Freytag‐type Reactions

Advanced Synthesis & Catalysis, Год журнала: 2023, Номер 365(19), С. 3211 - 3226

Опубликована: Авг. 26, 2023

Abstract Nitrogen radicals are one of the most useful reactive intermediates for selective transposition via intramolecular hydrogen atom transfer (HAT). The Hofmann‐Löffler‐Freytag (HLF) reaction is a distinctive radical‐based approach in which nitrogen used remote C−H bond functionalization HAT. Due to its excellent regioselectivity and atomic economy, HLF represents new preparation valuable functional molecules. In this review, we provide brief overview recent research advances mediated HLF‐type reactions involving intermolecular cyclization, δ ‐site functionalization.

Язык: Английский

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EDA Complex-Enabled Annulation to Access CF₂-Containing Tetralones and Quinazolinones Using Persulfates as Electron Donors

The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(15), С. 10614 - 10623

Опубликована: Июль 25, 2024

A photocatalyst-free and EDA complex-enabled radical cascade cyclization reaction of inactive alkenes with bromodifluoroacetamides was reported for the divergent synthesis fluorine-containing tetralones quinazolinones. In this transformation, persulfates as electron donors difluoro bromamide acceptors generate complex. This is a promising photochemical method advantages such mild conditions, simple operation, being metal-free, excellent functional group tolerance.

Язык: Английский

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The synthesis of seven- and eight-membered rings by radical strategies

Organic Chemistry Frontiers, Год журнала: 2022, Номер 9(17), С. 4757 - 4781

Опубликована: Янв. 1, 2022

Radical strategies for preparation of seven- or eight-membered rings.

Язык: Английский

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Metal-free and site-selective α-C–H functionalization of tetrahydrofuran enabled by the photocatalytic generation of bromine radicals

Green Chemistry, Год журнала: 2022, Номер 25(3), С. 960 - 965

Опубликована: Ноя. 3, 2022

A simple and inherent green photocatalytic approach using commercially available cheap n Bu 4 NBr with 4-CzIPN was reported to effectively initiate the site-selective α -C(sp 3 )-H activation of tetrahydrofuran for C-S C-C cross-couplings.

Язык: Английский

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Photochemical difluoromethylation of alkynes: synthesis of CF₂H-substituted seven-membered dioxodibenzothiazepines and dibenzazepines

Organic Chemistry Frontiers, Год журнала: 2023, Номер 10(8), С. 1968 - 1974

Опубликована: Янв. 1, 2023

A general and efficient photochemical strategy for difluoromethylation/radical cascade cyclization of alkynes with sodium difluoromethylsulfinate (NaSO 2 CF H) has been disclosed.

Язык: Английский

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