SynOpen,
Год журнала:
2022,
Номер
06(03), С. 198 - 207
Опубликована: Авг. 23, 2022
Abstract
An
efficient
organo-photocatalytic
method
for
the
synthesis
of
tetrasubstituted
pyrroles
bearing
a
ketone,
ester,
alcohol,
or
nitro
group
at
3-position
has
been
developed.
The
reaction
involves
visible-light-mediated
formal
[3+2]
dipolar
cycloaddition
between
2H-azirines
and
α-substituted
nitroalkenes
followed
by
denitration
debromination
sequence.
notable
features
protocol
are
excellent
regioselectivity,
wide
substrate
scope,
high
yields
products.
Chemical Communications,
Год журнала:
2023,
Номер
59(51), С. 7990 - 7993
Опубликована: Янв. 1, 2023
A
visible/solar-light-induced
electron-donor-acceptor
(EDA)-aggregated/mediated
radical
cyclization
between
(E)-2-(1,3-diarylallylidene)malononitriles
and
thiophenols
leads
to
poly-functionalized
pyridines.
The
two
reacting
partners
form
an
EDA
complex
that
absorbs
light
triggers
the
single-electron
transfer
(SET)
generate
a
thiol
radical,
which
undergoes
addition/cyclization
with
dicyanodiene
through
formation
of
C-S
C-N
bonds.
Croatica Chemica Acta,
Год журнала:
2022,
Номер
95(1)
Опубликована: Янв. 1, 2022
Visible
light
mediated
synthesis
of
benzoxazoles
from
benzanilides
under
an
air
atmosphere
at
room
temperature
is
reported
using
eosin
Y
as
organophotoredox
catalyst
by
functionalization
C-H/C-O
bond
formation.This
methodology
accepts
a
broad
range
functional
groups
and
affords
the
transition-metal-free
organic
photoredox
catalysis
very
mild
conditions.
The Journal of Organic Chemistry,
Год журнала:
2023,
Номер
88(3), С. 1533 - 1544
Опубликована: Янв. 19, 2023
A
four-component
synthesis
of
tetrasubstituted
pyrroles
was
developed
under
metal-free
conditions.
The
pyrrole
ring
formed
in
one
pot
through
[2
+
1
1]
condensation
using
ammonium
salt
as
the
nitrogen
source.
In
this
strategy,
1,4-naphthoquinones
and
maleimides
were
used
versatile
C2
fragments
to
provide
substituted
benzo[f]isoindole-4,9-diones
pyrrolo[3,4-c]pyrrole-1,3-diones,
respectively.
This
work
is
highlighted
by
source,
readily
available
starting
materials
multibond
formation
(two
C–C
two
C–N
bonds)
a
single
operation.
Chemistry - An Asian Journal,
Год журнала:
2024,
Номер
19(14)
Опубликована: Май 8, 2024
The
beginning
of
photochemical
reactions
revolutionized
synthetic
chemistry
through
sustainable
practices.
This
review
explores
cutting-edge
developments
in
leveraging
light-induced
processes
for
generating
cascaded
C-C
and
C-hetero
bonds
without
catalysts.
Significantly,
catalyst-free
photoinduced
methodologies
have
garnered
considerable
attention,
especially
the
creation
varied
heterocyclic
frameworks
drug
design
synthesis
natural
products.
article
delves
into
underlying
mechanisms,
addresses
limitations,
evaluates
various
methodologies,
emphasizing
potential
photocatalyst
transition
metal-free
to
enhance
sustainability.
Divided
two
sections,
it
covers
recent
strides
C-heteroatom
multiple
bond
formation
reactions.
The Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 2, 2025
A
photoredox-catalyzed
radical
cascade
cyclization
of
N-(o-cyanobiaryl)acrylamides
with
sulfonyl
chlorides
for
the
construction
sulfonyl-containing
pyrido[4,3,2-gh]phenanthridines
has
been
disclosed.
The
developed
synthetic
tool
tolerates
a
broad
range
to
undergo
sequence,
including
addition,
nitrile
insertion,
and
cyclization.
Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
366(9), С. 2101 - 2108
Опубликована: Март 5, 2024
Abstract
A
protocol
for
the
synthesis
of
trisubstituted
furans
via
phosphoric
acid‐catalyzed
regioselective
cascade
cyclization/amination
para
‐quinone
methides
(
p
‐QMs)
with
β
‐ketodinitriles
has
been
disclosed
first
time.
Various
kinds
‐QMs
and
can
effectively
produce
desired
polysubstituted
furan
derivatives
in
64–95%
yields,
demonstrating
high
atomic
economy
their
application
construction
heterocycles.
Preliminary
biological
activity
assay
suggests
that
these
have
potential
anticancer
activities.
The Journal of Organic Chemistry,
Год журнала:
2022,
Номер
87(16), С. 11112 - 11120
Опубликована: Авг. 8, 2022
A
metal-free
visible-light-induced
trifluoromethylation
of
Bunte
salts
α-bromoketones/alkyl
bromide/benzyl
bromides/functionalized
allyl
(Baylis-Hillman)
bromides
has
been
accomplished
using
Langlois'
reagent
in
the
presence
inexpensive
eosin
Y
as
a
photocatalyst
to
form
privileged
trifluoromethylthiolated
synthons.
The
method
is
straightforward,
operationally
simple,
and
endowed
with
broad
substrate
scope
good
functional
group
tolerance.
Chemistry - An Asian Journal,
Год журнала:
2023,
Номер
18(21)
Опубликована: Сен. 25, 2023
The
increasing
global
warming
concerns
have
propelled
a
surge
in
the
demand
for
sustainable
energy
sources
within
domain
of
synthetic
organic
chemistry.
A
particularly
prominent
area
research
has
been
development
mild
strategies
generating
heterocyclic
compounds.
Heterocyclic
compounds
containing
boron
notably
risen
to
prominence
as
pivotal
reagents
myriad
transformations,
showcasing
their
wide-ranging
applicability.
This
comprehensive
review
is
aimed
at
collecting
literature
pertaining
borylation
reactions
induced
by
light,
specifically
focusing
on
photocatalyst-free
and
transition
metal-free
methodologies.
central
emphasis
delving
into
selective
mechanistic
investigations.
amalgamation
analysis
these
insights
elucidate
substantial
potential
inherent
eco-friendly
approaches
synthesizing
compounds,
thus
propelling
landscape
Catalysis Science & Technology,
Год журнала:
2023,
Номер
14(1), С. 183 - 189
Опубликована: Ноя. 28, 2023
In
this
study,
we
demonstrate
the
proficiency
of
orthorhombic
CsPbBr
3
to
perform
C–H
chalcogenation
reactions
electron-rich
arenes
under
conditions
involving
polar
solvents,
aerobic
environments,
and
visible-light
irradiation.
