Advanced Synthesis & Catalysis,
Год журнала:
2023,
Номер
365(7), С. 1012 - 1019
Опубликована: Март 7, 2023
Abstract
We
have
developed
photoinduced
sulfonyl
radical‐triggered
cyclization
of
1,6‐dynes
without
metals,
oxidants,
or
additives.
During
the
reaction,
three
new
bonds
are
formed
(−SO
2
−C,
C−C,
and
C−I/C−Se−)
under
mild
conditions,
with
excellent
selectivity.
The
conversion
is
temporally
atomically
economical
easy
to
handle
even
on
a
gram
scale.
Detailed
mechanistic
studies
showed
that
reaction
proceeds
via
radical
pathway.
Subsequent
synthetic
transformations
products
produced
various
substituted
compounds.
Importantly,
we
observed
an
unprecedented
selective
C−C
single
bond
cleavage
boronic
acid
insertion
Suzuki
conditions.
magnified
image
Chemical Communications,
Год журнала:
2023,
Номер
59(42), С. 6391 - 6394
Опубликована: Янв. 1, 2023
A
novel
5-exo-dig/6-endo-trig
bicyclization
of
1,6-enynes
with
sulfonyl
hydrazides
in
the
aqueous
phase
using
cheap
and
available
tetrabutylammonium
iodide
(TBAI)-tert-butyl
hydroperoxide
(TBHP)
combined
system
is
reported.
The
resulting
reaction
diverse
nitrogen-
oxygen-polyheterocycles
displays
high
chemical
selectivity,
step-economy,
a
moderate
substrate
scope.
Moreover,
iodosulfonylation
can
be
realized
by
modulating
structure
1,6-enynes.
Organic Chemistry Frontiers,
Год журнала:
2023,
Номер
10(20), С. 5190 - 5197
Опубликована: Янв. 1, 2023
An
efficient
and
rapid
iron-catalyzed
oxosulfonylation
of
alkynes
with
small-ring
compounds
Na
2
S
O
5
for
the
synthesis
β
-keto
sulfones
has
been
developed.
Chemistry - An Asian Journal,
Год журнала:
2024,
Номер
19(14)
Опубликована: Май 8, 2024
The
beginning
of
photochemical
reactions
revolutionized
synthetic
chemistry
through
sustainable
practices.
This
review
explores
cutting-edge
developments
in
leveraging
light-induced
processes
for
generating
cascaded
C-C
and
C-hetero
bonds
without
catalysts.
Significantly,
catalyst-free
photoinduced
methodologies
have
garnered
considerable
attention,
especially
the
creation
varied
heterocyclic
frameworks
drug
design
synthesis
natural
products.
article
delves
into
underlying
mechanisms,
addresses
limitations,
evaluates
various
methodologies,
emphasizing
potential
photocatalyst
transition
metal-free
to
enhance
sustainability.
Divided
two
sections,
it
covers
recent
strides
C-heteroatom
multiple
bond
formation
reactions.
European Journal of Organic Chemistry,
Год журнала:
2024,
Номер
27(28)
Опубликована: Май 20, 2024
Abstract
In
recent
years,
the
functionalization
of
1,3‐butadiene
has
become
an
attractive
strategy
for
constructing
allyl
compounds
with
molecular
and
structural
complexity,
current
research
focuses
on
synthetic
chemistry
organic
synthesis.
Compared
traditional
synthesis
method,
methods
promoted
by
photochemistry
or
electrochemistry
represent
environmentally
friendly
mild
strategy.
this
review,
reactions
under
photochemical/electrochemical
processes
in
years
are
reviewed
according
to
classification
systems,
particular
emphasis
corresponding
reaction
mechanism,
which
lays
a
foundation
further
exploration
new
catalytic
methods.
Organic Letters,
Год журнала:
2022,
Номер
24(36), С. 6653 - 6657
Опубликована: Сен. 1, 2022
Switchable
in
situ
SO2
capture
and
CF3
migration
of
enol
triflates
with
peroxyl
compounds
under
iron
catalysis
are
presented.
By
regulating
the
structure
peroxides,
a
variety
keto-functionalized
dialkyl
sulfones
α-trifluoromethyl
ketones
were
selectively
synthesized
good
yields
mild
conditions.
The Journal of Organic Chemistry,
Год журнала:
2022,
Номер
87(19), С. 12877 - 12889
Опубликована: Сен. 8, 2022
We
report
the
visible-light-induced
Ph3P/LiI-promoted
intermolecular
cascade
trifluoromethyl
radical
addition/5-exo-dig
cyclization/iodination
of
1,6-enynes
with
Togni's
reagent
using
LiI
as
iodine
source
without
need
transition
metal,
oxidant,
and
base.
This
reaction
promises
to
be
a
useful
method
for
preparation
trifluoromethyl-substituted
vinyl
C-I
bond-containing
pyrrolidines
benzofuran
products
good
regioselectivity
functional-group
tolerance
under
ambient
conditions.
Chemical Communications,
Год журнала:
2023,
Номер
59(59), С. 9094 - 9097
Опубликована: Янв. 1, 2023
Herein,
this
work
describes
a
photoinduced
visible
light-mediated
radical
cyclization
for
constructing
dihydrobenzofuran
(DHB)
scaffolds.
Notably,
cascade
photochemical
process
is
tolerable
with
various
aromatic
aldehydes
and
diverse
alkynyl
aryl
ethers
proceeds
via
an
intramolecular
1,5-hydrogen
atom
transfer
(HAT)
pathway.
Significantly,
acyl
C-H
activation
under
mild
conditions
has
been
achieved
without
the
use
of
additives
or
reagents.
The
photocatalyst,
tetrabutylammonium
decatungstate
(TBADT),
plays
important
role
in
present
strategy
by
facilitating
well-known
hydrogen
during
course
reaction.
European Journal of Organic Chemistry,
Год журнала:
2023,
Номер
unknown
Опубликована: Авг. 31, 2023
Abstract
Achieving
high
molecular
complexity
can
be
not
trivial,
but
the
exploitation
of
domino
reactions
provides
an
atom‐
and
step‐economical
method
to
reach
this
target.
Over
past
decades,
a
lot
efforts
have
been
put
on
development
photocatalytic
cascades
employing
both
metal‐based
purely
organic
catalysts.
Despite
effectiveness
these
protocols,
catalyst‐
additive‐free
light‐induced
are
gaining
momentum
thank
their
efficiency,
operational
simplicity
sustainability.
The
increasing
number
papers
published
field
in
last
years
is
proof
appeal
transformations.
In
Review,
we
discuss
multicomponent
mediated
by
light
with
focus
photocatalyst‐
processes.
most
recent
advances
synthesis
complex
nitrogen‐,
oxygen‐,
sulphur‐
selenium‐heterocycles
together
analysed
emphasis
experimental
mechanistic
studies.
