Chemistry Letters, Год журнала: 2024, Номер 53(5)
Опубликована: Апрель 15, 2024
Abstract The rate constants for the radical addition of a trifluoromethyl to aryl-substituted vinyl triflates have been determined by applying competition kinetics at single concentration point. range from 4.1× 106 5.6× M−1 s−1 and depend on electronic properties benzene rings triflates.
Язык: Английский
The Journal of Organic Chemistry, Год журнала: 2024, Номер 89(11), С. 7656 - 7661
Опубликована: Май 15, 2024
A visible-light-triggered ring opening/in situ SO2-capture/alkynylation sequence of cyclopropyl alcohols with alkynyl triflones using 4CzIPN as a triplet energy transfer photocatalyst is herein described. This metal-free protocol provides straightforward and atom-economical approach to alkynyl-substituted γ-keto sulfones broad scope substituents. In this transformation, could be used both radical acceptors SO2 donors. Preliminary experimental mechanistic studies synthetic utility are also demonstrated.
Язык: Английский
Процитировано
5
Organic Letters, Год журнала: 2023, Номер 25(23), С. 4329 - 4334
Опубликована: Июнь 1, 2023
An inexpensive iron-catalyzed alkoxyl radical-induced C–C bond cleavage/gem-difluoroalkylation cascade is presented. Regulated by the structure of radical precursors, fluorinated distal diketones were synthesized through a ring-opening strategy and difluoroalkylated medium-sized lactones macrolactones constructed via ring-expansion strategy. Both protocols proceeded under mild redox neutral conditions with broad substrate scope good functional group compatibility.
Язык: Английский
Процитировано
9
Chemical Communications, Год журнала: 2023, Номер 59(88), С. 13175 - 13178
Опубликована: Янв. 1, 2023
An NHC organocatalytic radical acylation of cycloalkyl silyl peroxides with aldehydes was developed for the efficient and rapid synthesis long-chain 1,6-/1,7-/1,8-diketones, especially unsymmetrical ones.
Язык: Английский
Процитировано
9
Chinese Chemical Letters, Год журнала: 2023, Номер 35(6), С. 109263 - 109263
Опубликована: Окт. 30, 2023
Язык: Английский
Процитировано
8
Organic Letters, Год журнала: 2022, Номер 24(49), С. 9112 - 9117
Опубликована: Дек. 1, 2022
A straightforward three-component transformation for the preparation of functionalized benzosultams under TM-free and mild reaction conditions was described, in which easy-to-handle Na2S2O5, available bromodifluoroalkyl reagent, N-(2-haloaryl) cyanamide were employed. Na2S2O5 essential to generation difluoroalkyl radical, SO2 fixation, cyclization, enabled efficient construction target products a sustainable manner. broad substrate scope modular feature made this protocol attractive exploring chemical space cyclic sulfonamides.
Язык: Английский
Процитировано
12
Organic & Biomolecular Chemistry, Год журнала: 2023, Номер 21(43), С. 8744 - 8748
Опубликована: Янв. 1, 2023
A halotrimethylsilane facilitated cycloketonization of γ -hydroxyl ynones is detailed for one-step synthesis polysubstituted 3(2 H )-furanone products.
Язык: Английский
Процитировано
6
Chemical Communications, Год журнала: 2024, Номер 60(40), С. 5334 - 5337
Опубликована: Янв. 1, 2024
A photoredox-catalyzed alkylarylation of activated alkenes via a ring-opening/Truce–Smiles rearrangement cascade is developed. The protocol features broad substrate scope and excellent functional group compatibility.
Язык: Английский
Процитировано
2
Asian Journal of Organic Chemistry, Год журнала: 2022, Номер 12(1)
Опубликована: Дек. 15, 2022
Abstract An efficient synthesis of densely 1,2,4‐triazoles has been achieved by [3+2] cycloaddition nitrileimides with amidine hydrochlorides under transition metal‐free conditions. This method features mild reaction conditions, wide substrate scope and good functional group tolerance. A series aryl, heterocyclic alkyl substituted 3‐CF 3 ‐1,2,4‐triazoles were synthesized smoothly the promotion NaHCO yield up to 96%. In addition, both gram‐scale synthetic transformations are elaborated indicate utility this reaction.
Язык: Английский
Процитировано
7
Organic Process Research & Development, Год журнала: 2023, Номер 27(11), С. 1931 - 1953
Опубликована: Ноя. 1, 2023
This Review offers a comprehensive overview of the latest advancements in nonprecious metal catalysis (NPMC) research, focusing on period between July and October 2022. As part an ongoing review series, this account emphasizes diverse synthetic applications Ni, Cu, Fe catalysis. The noticeable surge NPMC publications reflects growing interest among academic industrial research laboratories exploring harnessing catalytic potential these metals.
Язык: Английский
Процитировано
4
Synlett, Год журнала: 2024, Номер unknown
Опубликована: Апрель 6, 2024
Abstract Sulfur-containing heterocycles, where the S(R) moiety is located within cyclic structure, have found tremendous applications in fields of chemical, pharmaceutical, and materials sciences due to their unique biological pharmaceutical activities. Recent years witnessed increasing interest sulfur-containing new methods for synthesis been reported by adopting modern methodologies technologies through insertion sulfur dioxide. The main objective this Account overview latest major developments on heterocyclic systems, mainly covering thermo-, photo- electron-induced cyclization dioxide (SO2). We aim provide readership with a comprehensive understanding topic offer positive outlook promising future field. 1 Introduction 2 Thermal-Induced Cyclization 3 Photoinduced Radical 4 Electron-Induced 5 Conclusion
Язык: Английский
Процитировано
1