Electrochemical N-acylation and N-α-ketoacylation of sulfoximines via the selective decarboxylation and dehydration of α-ketoacids
Green Chemistry,
Год журнала:
2023,
Номер
25(21), С. 8838 - 8844
Опубликована: Янв. 1, 2023
We
describe
an
electrochemical
N
-acylation
and
-α-ketoacylation
of
sulfoximines
via
the
selective
decarboxylation
dehydration
α-ketoacids
using
electricity
as
a
“traceless”
oxidant
α-ketoacid
“acyl”
or
“α-ketoacyl”
source.
Язык: Английский
Cobalt(III)-Catalyzed Directed C-7 Selective C–H Alkynylation of Indolines with Bromoalkynes
Organic Letters,
Год журнала:
2023,
Номер
25(29), С. 5411 - 5415
Опубликована: Июль 17, 2023
A
cobalt(III)-catalyzed
directed
C-7
alkynylation
of
indolines
with
easily
accessible
bromoalkynes
has
been
developed.
The
reaction
a
broad
substrate
scope
excellent
yields
and
represents
powerful
route
to
the
synthesis
7-alkynyl-substituted
indolines.
In
addition,
can
be
extended
coupling
N-aryl
7-azaindoles,
highlighting
synthetic
practicability
strategy.
Язык: Английский
Pd-Catalyzed C-7 Arylation of Indolines with Aryltriazenes under Mild Conditions
The Journal of Organic Chemistry,
Год журнала:
2023,
Номер
88(15), С. 11056 - 11068
Опубликована: Июль 18, 2023
A
palladium-catalyzed
direct
C-H
arylation
of
indolines
at
C-7
position
has
been
achieved
near-ambient
temperature.
The
reaction
was
carried
out
with
aryltriazene
as
a
stable
aryl
source
and
electron
shuttle
to
sustainably
release
radical
in
situ
under
the
action
promoter,
pyrimidine
detachable
directing
group
for
synthesis
7-arylindolines
oxidant-
ligand-free
conditions.
Notably,
this
catalytic
system
can
also
be
applied
site-selective
tetrahydroquinolines
(C-8)
carbazoles
(C-1).
Язык: Английский
Oxidative Nickel-Catalyzed ortho-C–H Amination of (Iso)quinolines with Alicyclic Amines Directed by a Sacrificial N-Oxide Group
Weiqi Zhu,
Wei Min,
Yanrui Wang
и другие.
Organic Letters,
Год журнала:
2024,
Номер
26(4), С. 912 - 916
Опубликована: Янв. 25, 2024
Transition
metal
(TM)-catalyzed
direct
amination
of
C–H
bonds
on
free
or
fused
pyridine
(Py)
rings
with
amines
still
remains
scarce
because
and
the
Py
ring
tend
to
adopt
a
nonproductive
N-bound
coordination
many
TMs,
leading
significant
decrease
catalytic
reactivity.
We
herein
disclose
nickel-catalyzed
sacrificial
N-oxide
group
directed
oxidative
coupling
(iso)quinolyl
alicyclic
amines,
which
furnishes
bioimportant
amino(iso)quinolines
efficiently
selectively
in
single
step.
Noteworthy,
this
protocol
avoids
use
aggressive
reactants
very
strong
bases
usually
required
when
aminating
nonoxidized
rings.
Язык: Английский
Ru(II)‐Catalyzed ortho C—H Allylation of N‐Aryl‐7‐azaindoles with 2‐Methylidene Cyclic Carbonate
Chinese Journal of Chemistry,
Год журнала:
2023,
Номер
42(9), С. 985 - 989
Опубликована: Дек. 26, 2023
Comprehensive
Summary
A
Ru(II)‐catalyzed
ortho
allylation
reaction
of
N
‐aryl‐7‐azaindole
with
readily
available
2‐methylidene
cyclic
carbonate
has
been
developed.
This
is
an
effective
pathway
for
synthesizing
7‐azaindole
derivatives
a
wide
scope
substrates
and
high
yields.
In
addition,
the
method
can
be
extended
to
other
heterocyclic
compounds
several
carbonates,
highlighting
practicality
this
strategy
synthesis.
Язык: Английский
Cobalt-Catalyzed Regioselective C8–H Sulfoxamination of 1-Naphthylamine Derivatives with NH-Sulfoximines
Nileshkumar B. Rathod,
Raj N. Patel,
Sachinkumar D. Patel
и другие.
The Journal of Organic Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 18, 2024
A
simple
cobalt-catalyzed,
picolinamide-directed
C8–H
sulfoxamination
of
1-naphthalamides
with
NH-sulfoximines
has
been
developed.
This
cross-dehydrogenative
C–H/N–H
coupling
reaction
offers
a
facile
route
to
N-arylated
sulfoximines,
exhibiting
high
yields,
broad
substrate
scope,
and
excellent
functional
group
tolerance
scalability.
Язык: Английский
Copper-catalyzed amination of arene
Scientia Sinica Chimica,
Год журнала:
2022,
Номер
53(3), С. 410 - 422
Опубликована: Ноя. 26, 2022
Aromatic
amines
are
widely
used
in
the
fields
of
natural
products,
pharmaceutical
chemistry
and
materials
science,
thus
new
methods
metal-catalyzed
C–N
bond
coupling
for
constructing
aromatic
always
have
been
focus
attention
chemists
scientific
community.
Copper,
as
a
catalyst
amination
arenes,
has
attracted
extensive
due
to
its
unique
catalytic
performance
variety
oxidation
states.
In
this
review,
recent
progress
construction
compounds
C(sp2)–N
catalyzed
by
copper
is
reviewed,
reaction
mechanisms
representative
reactions
briefly
described.
Язык: Английский