Abstract
This
review
delves
into
the
innovative
field
of
interfacial
photoelectrochemical
(iPEC)
and
(PEC)
catalysis,
dynamic
synthesis
methodologies
that
seamlessly
integrates
electrochemical
photoredox
catalysis
for
efficient
environmentally
friendly
reactions.
Utilizing
minute
quantities
photocatalysts,
visible
light
becomes
a
powerful
tool,
generating
transient
excited
states
to
catalyze
spectrum
reactions
through
single‐electron
oxidation
or
reduction
events.
The
categorizes
recent
advancements,
highlighting
applications
in
organic
synthesis,
late‐stage
modifications,
distinctive
features
methodology.
Despite
being
its
early
stages,
this
synergistic
approach
holds
great
promise
propelling
forward,
with
potential
large‐scale
diverse
functionalizations,
including
asymmetric
bioconjugation
strategies
biomolecule
modifications.
Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
366(6), С. 1325 - 1330
Опубликована: Фев. 2, 2024
Abstract
Copper‐catalyzed
silylarylation
of
N
‐(arylsulfonyl)acrylamides
via
a
tandem
silyl
radical
addition/1,4‐aryl
migration/desulfonylation
sequence
has
been
developed.
This
method
employs
silanes
as
the
precursor
and
di‐
tert
‐butyl
peroxide
(DTBP)
initiator.
By
using
this
cascade
procedure,
series
β
‐silyl
amide‐pharmaceutical
hybrids
which
contain
an
α
‐all‐carbon
quaternary
stereocenter
were
facilely
synthesized.
Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
366(10), С. 2352 - 2362
Опубликована: Апрель 5, 2024
Abstract
While
the
emergence
of
electrophotochemistry
provides
opportunities,
such
a
chemistry
at
this
stage
suffers
from
limited
reaction
types
and
high
photocatalyst
loadings.
A
self‐catalyzed
electrophotosynthesis
as
well
one
with
low
loading
is
presented.
These
external‐oxidant‐free
cyclizations
are
enabling
applicable
to
range
activated
alkenes,
affording
diverse
array
thiocyanato
heterocycles
including
4‐pyrrolin‐2‐ones,
isoquinoline‐1,3‐diones,
indolo[2,1‐
]isoquinolin‐6(5
H
)‐ones,
benzoimidazo[2,1‐
)‐ones
indolin‐2‐ones,
protocols
amenable
late‐stage
diversification
complex
molecular
architectures
gram‐scale
syntheses.
Sunlight
could
serve
light
source,
be
conducted
in
an
all‐solar‐driven
mode
using
commercially
available
photovoltaic
panel
produce
electricity.
Advanced Synthesis & Catalysis,
Год журнала:
2023,
Номер
365(8), С. 1205 - 1210
Опубликована: Март 22, 2023
Abstract
A
practical
electrochemical
Minisci‐type
reaction
for
the
synthesis
of
silylated
heterocycles
is
described.
Using
N
‐hydroxyphthalimide
(NHPI)
as
hydrogen
atom
transfer
(HAT)
catalyst
and
trialkylsilanes
silyl
radical
sources,
a
wide
range
electron‐deficient
in‐cluding
quinoline,
quinoxaline,
phthalazine,
3,6‐dichloropyridazine,
phenanthridine,
6‐chloroimidazo[1,2‐
b
]pyridazine
coumarin,
etc.
were
easily
converted
to
corresponding
products
in
37–83%
yields.
magnified
image
Abstract
This
review
delves
into
the
innovative
field
of
interfacial
photoelectrochemical
(iPEC)
and
(PEC)
catalysis,
dynamic
synthesis
methodologies
that
seamlessly
integrates
electrochemical
photoredox
catalysis
for
efficient
environmentally
friendly
reactions.
Utilizing
minute
quantities
photocatalysts,
visible
light
becomes
a
powerful
tool,
generating
transient
excited
states
to
catalyze
spectrum
reactions
through
single‐electron
oxidation
or
reduction
events.
The
categorizes
recent
advancements,
highlighting
applications
in
organic
synthesis,
late‐stage
modifications,
distinctive
features
methodology.
Despite
being
its
early
stages,
this
synergistic
approach
holds
great
promise
propelling
forward,
with
potential
large‐scale
diverse
functionalizations,
including
asymmetric
bioconjugation
strategies
biomolecule
modifications.
