Copper-catalyzed Larock-type cyclization/debenzylation of yne-allylic esters with aliphatic amines
Rongkang Huang,
Yuepeng Lu,
Feng Xu
и другие.
Science China Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 20, 2025
Язык: Английский
Ligand-Controlled Copper-Catalyzed Regiodivergent Sulfonylation of Yne-Vinyl Allylic Esters with Sodium Sulfinates
ACS Catalysis,
Год журнала:
2025,
Номер
unknown, С. 2415 - 2423
Опубликована: Янв. 27, 2025
Язык: Английский
Copper-Catalyzed Dual Remote Asymmetric Vinylogous Alkynylallylic Substitution of Yne-Allylic Esters with Coumarins
Organic Letters,
Год журнала:
2024,
Номер
26(30), С. 6407 - 6412
Опубликована: Июль 19, 2024
Chiral
coumarins
and
their
derivatives
are
ubiquitous
structural
motifs
found
in
an
array
of
biologically
therapeutically
active
natural
products
drugs.
Herein,
a
highly
enantioselective
dual
remote
copper-catalyzed
vinylogous
alkynylallylic
substitution
yne-allylic
esters
with
has
been
developed.
The
practicality
this
method
is
exemplified
by
the
use
readily
available
starting
materials;
mild
reaction
conditions;
excellent
regio-,
enantio-,
stereoselectivities;
very
broad
substrate
scope
(67
examples),
while
scalability
further
applications
illustrated
gram-scale
series
derivations
products.
Язык: Английский
Copper-catalyzed remote asymmetric yne-allylic substitution: construction of thiazolone derivatives with adjacent chiral centers
Organic Chemistry Frontiers,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
Herein,
we
report
a
highly
diastereo-
and
enantioselective
copper-catalyzed
remote
asymmetric
yne-allylic
substitution
of
esters
thiazolones.
Язык: Английский
Copper-catalyzed γ-selective yne-allylic substitution of vinyl ethynylethylene carbonates towards a formal [3 + 3] cycloaddition
Tetrahedron Letters,
Год журнала:
2025,
Номер
unknown, С. 155487 - 155487
Опубликована: Янв. 1, 2025
Язык: Английский
Synthesis of Axially Chiral N-Arylpyrroles through the Enantioselective Annulation of Yne-Allylic Esters with a Cooperative Copper-Squaramide Catalysis
Organic Letters,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 8, 2025
We
present
a
strategy
involving
central-to-axial
chirality
conversion
for
the
construction
of
axially
chiral
N-arylpyrroles
via
cooperative
copper-squaramide-catalyzed
remote
propargylic
amination/ring
closure/rearomatization
cascade
from
yne-allylic
esters.
The
reaction
exhibits
excellent
chemical
efficiency
and
enantioselectivity,
good
conversion.
use
squaramide
as
cocatalyst
is
crucial
success.
Язык: Английский
Copper-catalyzed yne-allylic substitutions: concept and recent developments
Beilstein Journal of Organic Chemistry,
Год журнала:
2024,
Номер
20, С. 2739 - 2775
Опубликована: Окт. 31, 2024
The
catalytic
(asymmetric)
allylation
and
propargylation
have
been
established
as
powerful
strategies
allowing
access
to
enantioenriched
α-chiral
alkenes
alkynes.
In
this
context,
combining
allylic
propargylic
substitutions
offers
new
opportunities
expand
the
scope
of
transition
metal-catalyzed
substitution
reactions.
Since
its
discovery
in
2022,
copper-catalyzed
yne-allylic
has
undergone
rapid
development
significant
progress
made
using
key
copper
vinyl
allenylidene
intermediates.
This
review
summarizes
developments
illustrates
influences
salt,
ligand,
pattern
substrate
on
regioselectivity
stereoselectivity.
Язык: Английский