Synthetic Strategies Toward 2H‐, 4H‐Pyrans, and Pyranones: Recent Advances
ChemistrySelect,
Год журнала:
2025,
Номер
10(21)
Опубликована: Май 30, 2025
Abstract
Pyrans
are
a
class
of
six‐membered
heterocyclic
rings
containing
five
carbon
atoms
and
one
oxygen
atom.
They
non‐aromatic
in
nature,
bearing
two
double
bonds
the
ring.
The
bond
position
distinguishes
pyran
isomers,
namely,
2
H
‐pyran
4
‐pyran.
When
saturated
sp
3
is
located
next
to
an
atom,
it
known
as
‐pyran,
when
at
4‐position
with
respect
In
1962,
by
thermal
breakdown
2‐acetoxy‐3,4‐dihydro‐2
‐pyrans
were
produced
for
first
time,
their
characteristics
explored.
Numerous
synthetic
methods
have
been
disclosed
over
time
owing
broad
applications
diverse
fields,
mainly
drug
design,
pharmaceuticals,
material
science.
this
review,
we
highlight
recent
advancements
toward
substituted
4‐pyranone,
2‐pyranones,
focusing
on
reports
published
from
2019
till
date,
which
play
important
roles
both
organic
synthesis
types
functional
molecules.
Язык: Английский
Synthetic Versatility: The C-P Bond Odyssey
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 15, 2024
The
review
thoroughly
examines
recent
progress
in
C–P
bond
formation
reactions
and
considers
the
future
directions
this
area
of
research.
Язык: Английский
Potassium Phosphate‐Mediated Synthesis of C4‐Phosphorylated Quinolines via Cascade Cycloisomerization of Ynones
Chemistry - A European Journal,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 5, 2024
Abstract
A
cascade
phosphorylation
cycloisomerization
of
readily
accessible
ynones
and
diphenylphosphine
oxides
facilitated
by
potassium
phosphate
is
described,
allowing
for
the
straightforward
synthesis
C4‐phosphorylated
quinoline
scaffolds.
The
formation
a
C−P
bond
C−N
achieved
in
single
procedure
without
need
pre‐assembled
cores
prior
to
phosphorylation.
This
transformation
operates
requirement
metals
or
oxidants
exhibits
excellent
compatibility
with
various
functional
groups.
Furthermore,
antimicrobial
activity
evaluation
demonstrated
that
synthesized
derivatives
exhibited
potent
inhibitory
against
Staphylococcus
aureus.
Язык: Английский