Polymers,
Год журнала:
2022,
Номер
14(15), С. 3126 - 3126
Опубликована: Июль 31, 2022
Temperature-induced,
rapid
changes
in
the
viscosity
and
reproducible
3-D
structure
formation
makes
thermos-sensitive
hydrogels
an
ideal
delivery
system
to
act
as
a
cell
scaffold
or
drug
reservoir.
Moreover,
hydrogels’
minimum
invasiveness,
high
biocompatibility,
facile
elimination
from
body
have
gathered
lot
of
attention
researchers.
This
review
article
attempts
present
complete
picture
exhaustive
arena,
including
synthesis,
mechanism,
biomedical
applications
thermosensitive
hydrogels.
A
special
section
on
intellectual
property
marketed
products
tries
shed
some
light
commercial
potential
International Journal of Polymer Science,
Год журнала:
2021,
Номер
2021, С. 1 - 16
Опубликована: Ноя. 30, 2021
Hydrogels
have
three-dimensional
network
structures,
high
water
content,
good
flexibility,
biocompatibility,
and
stimulation
response,
which
provided
a
unique
role
in
many
fields
such
as
industry,
agriculture,
medical
treatment.
Poly(vinyl
alcohol)
PVA
hydrogel
is
one
of
the
oldest
composite
hydrogels.
It
has
been
extensively
explored
due
to
its
chemical
stability,
nontoxic,
biological
aging
resistance,
water-absorbing
capacity,
easy
processing.
PVA-based
hydrogels
widely
investigated
drug
carriers,
articular
cartilage,
wound
dressings,
tissue
engineering,
other
intelligent
materials,
self-healing
shape-memory
supercapacitors,
sensors,
fields.
In
this
paper,
discovery,
development,
preparation,
modification
methods,
applications
functionalized
are
reviewed,
their
potential
future
research
trends
also
prospected.
Advanced Materials,
Год журнала:
2022,
Номер
34(34)
Опубликована: Июнь 27, 2022
Processing
tough
hydrogels
into
sophisticated
architectures
is
crucial
for
their
applications
as
structural
elements.
However,
Digital
Light
(DLP)
printing
of
challenging
because
the
low-speed
gelation
and
toughening
process.
Described
here
a
simple
yet
versatile
system
suitable
DLP
to
form
hydrogel
architectures.
The
aqueous
precursor
consists
commercial
photoinitiator,
acrylic
acid,
zirconium
ion
(Zr4+
),
readily
forming
metallo-supramolecular
under
digital
light
in
situ
formation
carboxyl-Zr4+
coordination
complexes.
high-stiffness
antiswelling
properties
as-printed
gel
enable
high-efficiency
high-fidelity
constructs.
Furthermore,
swelling-induced
morphing
also
achieved
by
encoding
structure
gradients
during
with
grayscale
light.
Mechanical
printed
are
further
improved
after
incubation
water
due
variation
local
pH
rearrangement
complex.
swelling-enhanced
stiffness
affords
shape
fixation
ability
manual
deformations,
thereby
provides
an
additional
avenue
more
complex
configurations.
These
used
devise
impact-absorption
element
or
high-sensitivity
pressure
sensor
proof-of-concept
examples.
This
work
should
merit
engineering
other
gels
extend
scope
diverse
fields.
Abstract
The
development
of
programmable
functional
biomaterials
makes
4D
printing
add
a
new
dimension,
time
(
t
),
based
on
3D
structures
x
,
y
z
therefore,
printed
constructs
could
transform
their
morphology
or
function
over
in
response
to
environmental
stimuli.
Nowadays,
highly
efficient
bone
defect
repair
remains
challenging
clinics.
Combining
biomaterials,
living
cells,
and
bioactive
factors,
bioprinting
provides
greater
potential
for
constructing
dynamic,
personalized,
precise
tissue
engineering
scaffolds
by
complex
structure
formation
maturation.
Therefore,
has
been
regarded
as
the
next
generation
technology.
This
review
focuses
its
advantages
orthopedics.
applications
different
smart
strategies
are
briefly
introduced.
Furthermore,
one
summarizes
recent
advancements
engineering,
uncovering
addressed
unaddressed
medical
requirements.
In
addition,
current
challenges
future
perspectives
further
discussed,
which
will
offer
more
inspiration
about
clinical
transformation
this
emerging
technology
regeneration.
Macromolecular Materials and Engineering,
Год журнала:
2022,
Номер
307(8)
Опубликована: Апрель 5, 2022
Abstract
Shape‐memory
materials
(SMMs)
combined
with
3D
printing
to
develop
dynamic
and
adaptive
products
which
are
responsive
physical,
chemical,
or
biological
stimuli.
These
structures
categorized
into
4D‐printed
(4DPed)
change
their
shape
properties
over
time
dimension.
4D
printing,
a
novel,
multidisciplinary,
futuristic
technology
is
expanding
its
utilization
in
different
applications
including
healthcare,
space,
textile,
soft
robotics,
defence,
sports,
aerospace,
automotive
sectors.
This
review
article
focuses
on
the
recent
insightful
developments
4DP
of
SMMs
especially
shape‐memory
polymers.
also
integrates
technologies,
programming
for
specific
actuating
mechanisms,
most
4DPed
structures/products.
Future
perspectives
countless
opportunities
this
outlined
address
current
challenges
will
help
evolve
promote
novel
as
mainstream
manufacturing
approach
developing
real‐world
myriad
engineering
progresses
beyond
imagination,
since
inception
technological
renaissance
material
science
field.
profoundly
impact
daily
human
life
future.
ACS Nano,
Год журнала:
2022,
Номер
16(2), С. 2640 - 2650
Опубликована: Янв. 24, 2022
Wound
healing
is
an
important
issue
for
regenerative
medicine.
Attempts
in
this
area
tend
to
develop
functional
wound
patches
promote
the
healing.
Here,
we
present
self-bonded
hydrogel
inverse
opal
particles
as
sprayed
flexible
patch
Such
were
fabricated
by
infusing
drugs-loaded
gelatin
(GT)
and
carrageenan
(CG)
pregel
into
scaffolds,
which
composed
of
biocompatible
hyaluronic
acid
methacryloyl
(HAMA)
(GelMA)
with
graphene
oxide
quantum
dots
(GO
QDs)
doping.
Due
photothermal
conversion
capability
GO
QDs
temperature
reversible
phase-changing
performance
GT/CG,
hybrid
could
undergo
GT/CG
liquid
transformation
under
near-infrared
(NIR)
irradiation,
made
them
adhere
each
other
finally
form
a
patch.
Following
phase-change
hydrogel,
encapsulated
drugs
also
controllably
released
from
scaffold.
As
scaffolds
maintained,
their
drug
release
induced
refractive
index
changes
be
detected
visual
structural
color
shifting,
utilized
monitor
delivery
processes.
Based
on
these
features,
have
demonstrated
that
particles,
administered
spray,
applied
tissue
monitoring.
These
results
indicate
potential
value
multifunctional
clinical
applications.
Abstract
Stimuli‐responsive
fluorescent
hydrogels
are
three‐dimensional
networked
polymeric
materials
with
tunable
luminescence
and
dynamic
properties,
which
play
an
important
role
as
a
water‐rich
soft
material
in
the
fields
of
information
encryption,
bionic
actuation,
bioimaging,
environmental
monitoring,
luminescent
materials.
Compared
conventional
hydrogels,
their
unique
properties
allow
visualization
microscopic
dynamics
within
polymer
network.
By
rational
inclusion
motifs,
such
photoswitches,
AIEgens,
lanthanide
complexes,
host–guest
these
endowed
tunability
emission,
shape,
phase
time
space
response
to
effectors.
In
this
review,
we
summarize
fabrication
strategies
that
mainly
used
by
recently
reported
stimuli‐responsive
applications
