Crystal Growth & Design,
Год журнала:
2024,
Номер
24(5), С. 2235 - 2265
Опубликована: Фев. 26, 2024
Metal-organic
frameworks
(MOFs),
formed
by
the
combination
of
both
inorganic
and
organic
components,
have
attracted
special
attention
for
their
tunable
porous
structures,
chemical
functional
diversities,
enormous
applications
in
gas
storage,
catalysis,
sensing,
etc.
Recently,
electronic
MOFs
like
electrocatalysis,
supercapacitors,
batteries,
electrochemical
etc.,
become
a
major
research
topic
MOF
chemistry.
However,
low
electrical
conductivity
most
represents
handicap
development
these
emerging
applications.
To
overcome
limitations,
different
strategies
been
developed
to
enhance
implementation
devices.
In
this
review,
we
outline
all
employed
increase
conduction
intrinsically
(framework-modulated)
extrinsically
(guests-modulated)
conducting
MOFs.
Molecules,
Год журнала:
2022,
Номер
27(14), С. 4529 - 4529
Опубликована: Июль 15, 2022
Enzymatic
biocatalysis
is
a
sustainable
technology.
Enzymes
are
versatile
and
highly
efficient
biocatalysts,
have
been
widely
employed
due
to
their
biodegradable
nature.
However,
because
the
three-dimensional
structure
of
these
enzymes
predominantly
maintained
by
weaker
non-covalent
interactions,
external
conditions,
such
as
temperature
pH
variations,
well
presence
chemical
compounds,
can
modify
or
even
neutralize
biological
activity.
The
enablement
this
category
processes
result
several
advances
in
areas
molecular
biology
biotechnology
achieved
over
past
two
decades.
In
scenario,
metal–organic
frameworks
(MOFs)
highlighted
supports
for
enzyme
immobilization.
They
be
used
‘house’
specific
enzyme,
providing
it
with
protection
from
environmental
influences.
This
review
discusses
MOFs
structures;
emphasizes
synthesis
strategies,
properties,
applications;
explores
existing
methods
using
immobilization
various
enzymes;
lists
possible
modifications
combinations
other
compounds
formulate
ideal
given
application.
Chemical Society Reviews,
Год журнала:
2023,
Номер
52(7), С. 2528 - 2543
Опубликована: Янв. 1, 2023
Self-assembly
of
colloidal
particles
into
ordered
superstructures
enables
the
development
novel
advanced
materials
for
diverse
applications
such
as
photonics,
electronics,
sensing,
energy
conversion,
storage,
diagnosis,
drug
or
gene
delivery,
and
catalysis.
Recently,
polyhedral
metal-organic
framework
(MOF)
have
been
proposed
promising
to
form
superstructures,
based
on
their
stability,
size-tunability,
rich
shapes,
porosity
multifunctionality.
In
this
review,
we
present
a
comprehensive
overview
strategies
self-assembly
MOF
different
dimensionalities,
highlighting
some
properties
applications,
sharing
thoughts
particles.
Journal of Materials Chemistry B,
Год журнала:
2023,
Номер
11(25), С. 5693 - 5714
Опубликована: Янв. 1, 2023
Cancer
is
one
of
the
greatest
challenges
in
medical
science
today
as
it
poses
a
serious
threat
to
human
life.
In
view
this,
myriad
therapeutic
strategies
are
being
developed
for
treatment
cancer.
Despite
use
various
approaches,
they
still
insufficient
The
rapid
advancement
nanotechnology
currently
offers
exciting
possibilities
creation
novel
cancer
therapy
approaches.
Metal
organic
frameworks
(MOFs)
emerging
multifunctional
nanomaterials
that
find
prospective
applications
biomedical
field
owing
their
porosity,
large
specific
surface
area,
and
diversified
structures.
Amongst
varied
categories
MOFs,
Hf(IV)-based
MOFs
have
been
since
2012
finding
new
hence
this
class
gaining
immense
attention
amongst
material
biomaterial
chemists.
Most
importantly,
Hf(IV)-MOFs
comprising
high
Z-Hf
metal
content
may
be
capable
offering
options
therapy,
nonlinear
optics,
fluorescent
sensors,
photoresponsive
devices.
review,
progress
using
radiotherapy,
chemotherapy,
immunotherapy,
phototherapeutic
techniques,
or
combination
two
more
these
techniques
explored.
This
review
also
provides
insight
regarding
current
limitations
future
prospects
therapy.
Dalton Transactions,
Год журнала:
2023,
Номер
52(19), С. 6226 - 6238
Опубликована: Янв. 1, 2023
This
review
focuses
on
the
application
of
platinum
as
an
anticancer
drug
and
MOF
materials
loading
species;
prospect
for
its
future
development
is
also
discussed.
Abstract
Nano‐immunotherapy
has
been
recognized
as
a
highly
promising
strategy
for
cancer
treatment
in
recent
decades,
which
combines
nanotechnology
and
immunotherapy
to
combat
against
tumors.
Hybrid
nanomaterials
consisting
of
at
least
two
constituents
with
distinct
compositions
properties,
usually
organic
inorganic,
have
engineered
integrated
functions
enormous
potential
boosting
immunotherapy.
This
review
provides
summary
hybrid
reported
immunotherapy,
including
nanoscale
metal–organic
frameworks,
metal–phenolic
networks,
mesoporous
organosilica
nanoparticles,
metallofullerene
nanomaterials,
polymer–lipid,
biomacromolecule‐based
nanomaterials.
The
combination
chemotherapy,
chemodynamic
therapy,
radiotherapy,
radiodynamic
photothermal
photodynamic
sonodynamic
therapy
based
on
is
also
discussed.
Finally,
the
current
challenges
prospects
designing
their
application
are
outlined.
Chemical Reviews,
Год журнала:
2023,
Номер
123(12), С. 7782 - 7853
Опубликована: Май 15, 2023
The
high
selectivity
and
affinity
of
antibodies
toward
their
antigens
have
made
them
a
highly
valuable
tool
in
disease
therapy,
diagnosis,
basic
research.
A
plethora
chemical
genetic
approaches
been
devised
to
make
accessible
more
"undruggable"
targets
equipped
with
new
functions
illustrating
or
regulating
biological
processes
precisely.
In
this
Review,
addition
introducing
how
naked
various
antibody
conjugates
(such
as
antibody-drug
conjugates,
antibody-oligonucleotide
antibody-enzyme
etc.)
work
therapeutic
applications,
special
attention
has
paid
chemistry
tools
helped
optimize
the
outcome
(i.e.,
enhanced
efficacy
reduced
side
effects)
facilitate
multifunctionalization
antibodies,
focus
on
emerging
fields
such
targeted
protein
degradation,
real-time
live-cell
imaging,
catalytic
labeling
decaging
spatiotemporal
control
well
engagement
inside
cells.
With
advances
modern
biotechnology,
well-designed
derivatives
via
size
miniaturization
together
efficient
delivery
systems
emerged,
which
gradually
improved
our
understanding
important
paved
way
pursue
novel
for
potential
treatments
diseases.
Advanced Healthcare Materials,
Год журнала:
2023,
Номер
12(19)
Опубликована: Март 20, 2023
Chronic
wound
healing
is
a
major
challenge
in
biomedicine.
Conventional
therapies
are
usually
associated
with
poor
drug
permeability,
low
bioavailability,
risk
of
antimicrobial
resistance,
and
require
frequent
administration.
Therefore,
novel
formulation
reduced
antibiotic
dosage,
improved
delivery
efficiency,
application
frequency
remarkable
interest
for
chronic
healing.
Herein,
multifunctional
microneedle
(MN)
patch
presented
to
achieve
rapid
via
efficient
chemo-photodynamic
antibacterial
effect
sustained
release
growth
factors
at
the
bed.
When
MN
pierces
skin,
tips
carrying
both
dosage
antibiotics
bioactive
small
molecule-encapsulated
metal-organic
frameworks
(MOFs)
rapidly
dissolve
subsequently
deliver
payloads
wound.
Upon
light
irradiation,
MOF-based
nanoparticles
robustly
convert
O2
into
1
,
which
acts
synergistically
chemotherapy
remove
pathogenic
bacteria
from
wound,
exhibiting
excellent
performance
tenfold
reduction
required
amount.
The
can
continuous
tissue,
promoting
formation
epithelial
tissue
neovascularization,
thereby
further
accelerating
Collectively,
designed
patches
offer
simple,
safe,
effective
alternative
management.
