Colloids and Surfaces B Biointerfaces, Год журнала: 2024, Номер 239, С. 113939 - 113939
Опубликована: Май 2, 2024
Язык: Английский
Applied Microbiology, Год журнала: 2023, Номер 3(1), С. 145 - 174
Опубликована: Янв. 27, 2023
Many publications report coatings that exhibit antimicrobial potency applicable to high-touch surfaces and desirable for healthcare settings contribute reductions in the occurrence of Hospital Acquired Infections (HAI). In this review, importance surface contamination transmission microbes is addressed. The standard strategy tackle fomites implement proper disinfection cleaning practices periodically monitor environment’s cleanliness. However, probability recontamination cleaned high. Therefore, an additional first line defense against pathogen subsequent infection can eliminate or at least repel pathogens, introducing a barrier spread infection. It simple concept, but formulating durable, coating with broad-spectrum antifouling activities has proven challenging. challenges progress made developing such material are reviewed.
Язык: Английский
Процитировано
33
Journal of Material Science and Technology, Год журнала: 2023, Номер 169, С. 209 - 219
Опубликована: Июль 17, 2023
Язык: Английский
Процитировано
32
Acta Biomaterialia, Год журнала: 2023, Номер 170, С. 389 - 400
Опубликована: Авг. 23, 2023
Язык: Английский
Процитировано
31
Materials Today Bio, Год журнала: 2023, Номер 23, С. 100827 - 100827
Опубликована: Окт. 2, 2023
Biofilms are aggregates of organized microbial growth that function as barriers and create a stable internal environment for cell survival. The bacteria in the biofilms exhibit characteristics quite different from planktonic bacteria, such strong resistance to antibiotics other bactericides, getting out host immunity, developing harsh environments, which all contribute persistent intractable treatment. Hence, there is an urgent need develop novel materials strategies combat biofilms. However, most reviews on anti-biofilms published recent years based specific fields or materials. Microorganisms ubiquitous, except context medical health issues; however, exert detrimental effects advancement progress various fields. Therefore, this review aims provide comprehensive summary effective methodologies applicable across industries. Firstly, process formation was introduced enhance our comprehension "enemy". Secondly, intervene important links were discussed, taking timely action during early weak stages Thirdly, treatment mature summarized deal with break through defense line. Finally, several substances antibacterial properties presented. concludes standpoint author about potential developments strategies. This may help researchers quickly understand research challenges field design more efficient methods
Язык: Английский
Процитировано
27
Langmuir, Год журнала: 2025, Номер unknown
Опубликована: Март 3, 2025
Bioactive surfaces play a pivotal role in biomedical applications by enabling precise biological interactions through immobilized functional molecules. However, their performance is often hindered nonspecific protein adsorption and cell adhesion. Antifouling polymer coatings have emerged as an effective solution, creating hydration barriers to preserve functionality reduce biofouling. This review provides overview of the recent advances development antifouling for bioactive surfaces, with particular focus on nonionic polymers, such polyethylene glycol (PEG), zwitterionic polymers like poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC). Among them, unique charge-balanced structures, exhibit exceptional hydration, resistance, stability, making them particularly promising applications. In addition, key these including use anticoagulant materials, antibacterial coatings, biosensor interfaces, are also discussed. The discussion concludes address field's challenges future directions, highlighting need innovative materials that balance properties, biocompatibility, long-term stability both clinical industrial use. aims latest advancements provide insights into optimizing multifunctional meet evolving dynamic demands field.
Язык: Английский
Процитировано
2
Journal of Material Science and Technology, Год журнала: 2021, Номер 110, С. 14 - 23
Опубликована: Ноя. 9, 2021
Язык: Английский
Процитировано
44
International Journal of Biological Macromolecules, Год журнала: 2023, Номер 237, С. 124177 - 124177
Опубликована: Март 25, 2023
Язык: Английский
Процитировано
22
ACS Applied Materials & Interfaces, Год журнала: 2024, Номер 16(15), С. 18360 - 18385
Опубликована: Апрель 4, 2024
Bacterial keratitis (BK) causes visual morbidity/blindness if not treated effectively. Here, ciprofloxacin (CIP)-loaded nanoparticles (NPs) using glycol chitosan (GC) and poly(lactic acid) (PLA) conjugate at three different ratios (CIP@GC(PLA) NPs (1:1,5,15)) were fabricated. CIP@GC(PLA) (1:1) more effective than other tested ratios, indicating the importance of optimal hydrophobic/hydrophilic balance for corneal penetration preventing bacterial invasion. The realized highest association with human epithelial cells, which nonirritant to hen's egg-chorioallantoic membrane test (HET-CAM test) demonstrated significant antibacterial response in vitro minimum inhibitory, bactericidal, live-dead zone inhibition, biofilm inhibition assays against keratitis-inducing pathogen Pseudomonas aeruginosa. antiquorum sensing activity GC has been explored first time. disrupted quorum by inhibiting production virulence factors, including acyl homoserine lactones, pyocyanin, motility, caused downregulation associated genes. In vivo studies, displayed ocular retention (∼6 h) decreased opacity load Overall, NP is a biofilm-disrupting treatment regimen clinical translation potential BK.
Язык: Английский
Процитировано
7
Applied Surface Science, Год журнала: 2022, Номер 589, С. 153019 - 153019
Опубликована: Март 9, 2022
Язык: Английский
Процитировано
26
Composites Part B Engineering, Год журнала: 2022, Номер 244, С. 110143 - 110143
Опубликована: Июль 31, 2022
Язык: Английский
Процитировано
25