Kagome-topology 2D covalent organic frameworks assembled from D2h-symmetric and non-centrosymmetric C2-symmetric blocks for photothermal imaging DOI
Jiahao Li, Guinan Chen, Chunhong Chen

и другие.

Chemical Communications, Год журнала: 2023, Номер 59(88), С. 13191 - 13194

Опубликована: Янв. 1, 2023

2D COFs with kagome-topology are synthesized using 4-connected D 2h -symmetric and 2-connected non-centrosymmetric C 2 building blocks, showcasing remarkable photothermal imaging performance.

Язык: Английский

An H2S‐BMP6 Dual‐Loading System with Regulating Yap/Taz and Jun Pathway for Synergistic Critical Limb Ischemia Salvaging Therapy DOI

Jiateng Hu,

Zhijue Xu,

Donghui Liao

и другие.

Advanced Healthcare Materials, Год журнала: 2023, Номер 12(28)

Опубликована: Авг. 2, 2023

Critical limb ischemia, the final course of peripheral artery disease, is characterized by an insufficient supply blood flow and excessive oxidative stress. H2 S molecular therapy possesses huge potential for accelerating revascularization scavenging intracellular reactive oxygen species (ROS). Moreover, it found that BMP6 most significantly up-expressed secreted protein-related gene in HUVECs treated with GYY4137, a donor, based on transcriptome analysis. Herein, UIO-66-NH2 @GYY4137@BMP6 co-delivery nanoplatform to strengthen therapeutic effects ischemia developed. The established exerts its proangiogenic anti-oxidation functions regulating key pathways. underlying mechanisms dual-loading system lie upregulation phosphorylated YAP/TAZ Jun promote proliferation downregulation p53/p21 scavenge ROS. Meanwhile, laser-doppler perfusion imaging (LDPI), injury severity evaluation, histological analysis confirm excellent vivo. This work may shed light treatment critical YAP, Jun, p53 signaling pathways gas-protein synergistic therapy.

Язык: Английский

Процитировано

57
pH-sensitive ameliorated quercetin delivery using graphene oxide nanocarriers coated with potential anticancer gelatin-polyvinylpyrrolidone nanoemulsion with bitter almond oil DOI Creative Commons

Amin Pirali Najafabadi,

Mehrab Pourmadadi, Fatemeh Yazdian

и другие.

Journal of Drug Delivery Science and Technology, Год журнала: 2023, Номер 82, С. 104339 - 104339

Опубликована: Март 10, 2023

The rapid rise of cancer worldwide demonstrates the importance treatment strategies. In addition to reduce side effects conventional treatments, targeted drug delivery systems increase performance and effectiveness. this research, nanocarriers comprising gelatin (G)-polyvinylpyrrolidone (PVP) coated graphene oxide (GO) were prepared for first time. nanocarries loaded with quercetin (QC) a dual nanoemulsion water/oil/water bitter almond oil was developed as membrane around nanocomposite control further release. XRD, FTIR, FESEM, DLS analysis confirmed success synthesis loading. resulting pH-sensitive system showed an 87.5% encapsulation efficiency 45% loading, which are among highest values reported up date. zeta potential nanocomposites about −40 mV, indicating good stability. release kinetics followed Higuchi model, presence resulted in better entrapping efficiency, controlled long-term MTT assay flow cytometry methods revealed rate cell death 53.14%, 36.51% apoptotic phase. Taking into account results obtained herein, PVP-G-GO-QC can be considered new promising treatment.

Язык: Английский

Процитировано

44
Advances in covalent organic frameworks for cancer phototherapy DOI
Nem Singh, Miae Won, Jusung An

и другие.

Coordination Chemistry Reviews, Год журнала: 2024, Номер 506, С. 215720 - 215720

Опубликована: Фев. 16, 2024

Язык: Английский

Процитировано

20
A review of covalent organic frameworks for metal ion fluorescence sensing DOI
Deshuai Zhen, Chunlin Liu,

Qiuhui Deng

и другие.

Chinese Chemical Letters, Год журнала: 2023, Номер 35(8), С. 109249 - 109249

Опубликована: Окт. 29, 2023

Язык: Английский

Процитировано

39
Drug delivery using biocompatible covalent organic frameworks (COFs) towards a therapeutic approach DOI
Pritam Ghosh, Priyabrata Banerjee

Chemical Communications, Год журнала: 2023, Номер 59(84), С. 12527 - 12547

Опубликована: Янв. 1, 2023

COFs are used for multiple drug encapsulation/decapsulation in the biological medium and would be potential contenders clinical applications.

Язык: Английский

Процитировано

30
Self-stablized monodispersing nano-MOFs for controlled enzyme delivery DOI
Peiwei Gong,

Huiying Cui,

Cheng Li

и другие.

Chemical Engineering Journal, Год журнала: 2024, Номер 489, С. 150941 - 150941

Опубликована: Апрель 16, 2024

Язык: Английский

Процитировано

17
Understanding the Mechanisms and Applications of Luminescent Covalent Organic Frameworks (COFs) for Multi-Analyte Sensing DOI
R. Arvind Singh, Brij Mohan, Neera Raghav

и другие.

Journal of Molecular Structure, Год журнала: 2024, Номер 1321, С. 139945 - 139945

Опубликована: Сен. 7, 2024

Язык: Английский

Процитировано

14
Enzyme coordination conferring stable monodispersity of diverse metal–organic frameworks for photothermal/starvation therapy DOI
Peiwei Gong, Cheng Li, Dandan Wang

и другие.

Journal of Colloid and Interface Science, Год журнала: 2023, Номер 642, С. 612 - 622

Опубликована: Март 31, 2023

Язык: Английский

Процитировано

20
Phospholipid-inspired alkoxylation induces crystallization and cellular uptake of luminescent COF nanocarriers DOI
Wei Zhang, Shuo Xiang, Yuxin Han

и другие.

Biomaterials, Год журнала: 2024, Номер 306, С. 122503 - 122503

Опубликована: Фев. 7, 2024

Язык: Английский

Процитировано

9
Focused starvation of tumor cells using glucose oxidase: A comprehensive review DOI
Shivanshu Agrawal, Gireesh Kumar Singh, Sanjay Tiwari

и другие.

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 281, С. 136444 - 136444

Опубликована: Окт. 9, 2024

Язык: Английский

Процитировано

8